Evaluation of pregnancy and delivery in 13 women who underwent resection of a sacrococcygeal teratoma during early childhood

BMC Pregnancy and Childbirth

Ernest LW van Heurn³  David C van der Zee⁴  René MH Wijnen⁶  Marc HWA Wijnen⁷  Hugo A Heij¹  Robertine van Baren²  Audrey Coumans⁵  Joep PM Derikx³  Margot M Koeneman⁵  Marijke EB Kremer³ 

[1] Pediatric Surgical Center of Amsterdam, Emma Children’s Hospital University Medical Center and VU Medical Center, Amsterdam, The Netherlands;Department of Pediatric Surgery, University Medical Center Groningen, Groningen, The Netherlands;Department of Pediatric Surgery, Maastricht University Medical Center, Maastricht, The Netherlands;Department of Pediatric Surgery, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands;Department of Gynecology and Obstetrics, Maastricht University Medical Center, Maastricht, The Netherlands;Department of Pediatric Surgery, Sophia Children’s Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands;Department of Pediatric Surgery, University Medical Center Nijmegen, Nijmegen, The Netherlands

关键词: Vaginal delivery;    Pregnancy;    Sequelae;    Sacrococcygeal teratoma;   

Others  :  1090942
DOI  :  10.1186/s12884-014-0407-x

 received in 2014-09-16, accepted in 2014-11-27,  发布年份 2014

【 摘 要 】

Background

Sacrococcygeal teratoma resection often brings changes in pelvic anatomy and physiology with possible consequences for defecation, micturition and sexual function. It is unknown, whether these changes have any gynecological and obstetric sequelae. Until now four pregnancies after sacrococcygeal teratoma resection have been described and cesarean section has been suggested to be the method of choice for delivery. We evaluated the pregnancy course and mode of delivery in women previously treated for a sacrococcygeal teratoma.

Methods

The records of all patients who underwent sacrococcygeal teratoma resection after 1970 in one of the six pediatric surgical centers in the Netherlands were reviewed retrospectively. Women aged 18 years and older were eligible for participation. Patient characteristics, details about the performed operation and tumor histology were retrieved from the records. Consenting participants completed a questionnaire addressing fertility, pregnancy and delivery details.

Results

Eighty-nine women were eligible for participation; 20 could not be traced. Informed consent was received from 41, of whom 38 returned the completed questionnaire (92.7%). Thirteen of these 38 women conceived, all but one spontaneously. In total 20 infants were born, 17 by vaginal delivery and 3 by cesarean section, in one necessitated by previous intra-abdominal surgery as a consequence of sacrococcygeal teratoma resection. Conversion to a cesarean section was never necessary. None of the 25 women without offspring reported involuntary childlessness.

Conclusions

There are no indications that resection of a sacrococcygeal teratoma in female patients is associated with reduced fertility: spontaneous pregnancy is possible and vaginal delivery is safe for mother and child, irrespective of the sacrococcygeal teratoma classification or tumor histology.

【 授权许可】

   
2014 Kremer et al.; licensee BioMed Central Ltd.

【 图 表 】

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