Association between iron status, iron deficiency anaemia, and severe early childhood caries: a case–control study

BMC Pediatrics

Michael EK Moffatt²  James Friel¹  Eleonore Kliewer¹  Jeremy Levi¹  Robert J Schroth¹ 

[1]The Manitoba Institute of Child Health, 507 – 715 McDermot Avenue, Winnipeg, MB, R3E 3P4, Canada

[2]Winnipeg Regional Health Authority, 4th Floor – 650 Main Street, Winnipeg, MB, R3B 1E2, Canada

关键词: Preschool child;    Anaemia;    Iron deficiency;    Iron;    Early childhood caries;   

Others  :  1164256
DOI  :  10.1186/1471-2431-13-22

 received in 2012-09-25, accepted in 2013-02-05,  发布年份 2013

【 摘 要 】

Background

Severe tooth decay is known to affect the health and well-being of young children. However, little is known about the influence of Severe Early Childhood Caries (S-ECC) on childhood nutritional status. The purpose of this study was to contrast ferritin and haemoglobin levels between preschoolers with S-ECC and caries-free controls.

Methods

Children were recruited as part of a larger case–control study examining differences in nutritional status between those with and without S-ECC. Preschoolers with S-ECC were recruited on the day of their dental surgery, while caries-free controls were recruited from the community. Parents completed a questionnaire and the child underwent venipuncture. The study was approved by the University’s Health Research Ethics Board. Statistics included descriptive, bivariate and logistic regression analyses. A p value ≤ .05 was significant. A total of 266 children were recruited; 144 with S-ECC and 122 caries-free.

Results

The mean age was 40.8 ± 14.1 months. The mean ferritin concentration for all children was 29.6 ± 17.9 μg/L while the mean haemoglobin level was 115.1 ± 10.1 g/L. Children with S-ECC were significantly more likely to have low ferritin (p=.033) and low haemoglobin levels (p>.001). Logistic regression analyses revealed that children with S-ECC were nearly twice as likely to have low ferritin levels and were over six times more likely to have iron deficiency anaemia than caries-free controls.

Conclusions

Children with S-ECC appear to be at significantly greater odds of having low ferritin status compared with caries-free children and also appear to have significantly lower haemoglobin levels than the caries-free control group. Children with S-ECC also appear to be at significantly greater odds for iron deficiency anaemia than cavity-free children.

【 授权许可】

   
2013 Schroth et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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