Prospective observational cohort study of Health Related Quality of Life (HRQOL), chronic foot problems and their determinants in gout: a research protocol

BMC Musculoskeletal Disorders

Edward Roddy¹  Irena Zwierska¹  Simon Wathall¹  Jennifer Titley¹  Charlotte Purcell¹  Sara Muller¹  Zoe Mayson¹  Jane Mason¹  Samantha Hider¹  Rajvinder Gill¹  Joanne Bailey¹  Keith Rome²  Jane Richardson¹  Christian Mallen¹  Priyanka Chandratre¹ 

[1] Arthritis Research UK Primary Care Centre, Keele University, Staffordshire, ST5 5BG, UK;Health and Rehabilitation Research Institute and School of Podiatry, AUT University, Auckland, 0627, New Zealand

关键词: Primary care;    Prospective cohort;    Patient experience;    Foot;    HRQOL;    Gout;   

Others  :  1135730
DOI  :  10.1186/1471-2474-13-219

 received in 2012-10-09, accepted in 2012-11-07,  发布年份 2012

【 摘 要 】

Background

Gout is the commonest inflammatory arthritis affecting around 1.4% of adults in Europe. It is predominantly managed in primary care and classically affects the joints of the foot, particularly the first metatarsophalangeal joint. Gout related factors (including disease characteristics and treatment) as well as comorbid chronic disease are associated with poor Health Related Quality of Life (HRQOL) yet to date there is limited evidence concerning gout in a community setting. Existing epidemiological studies are limited by their cross-sectional design, selection of secondary care patients with atypical disease and the use of generic tools to measure HRQOL. This 3 year primary care-based prospective observational cohort study will describe the spectrum of HRQOL in community dwelling patients with gout, associated factors, predictors of poor outcome, and prevalence and incidence of foot problems in gout patients.

Methods

Adults aged ≥ 18 years diagnosed with gout or prescribed colchicine or allopurinol in the preceding 2 years will be identified through Read codes and mailed a series of self-completion postal questionnaires over a 3-year period. Consenting participants will have their general practice medical records reviewed.

Discussion

This is the first prospective cohort study of HRQOL in patients with gout in primary care in the UK. The combination of survey data and medical record review will allow an in-depth understanding of factors that are associated with and lead to poor HRQOL and foot problems in gout. Identification of these factors will improve the management of this prevalent, yet under-treated, condition in primary care.

【 授权许可】

   
2012 Chandratre et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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