Zinc and copper levels in low birth weight deliveries in Medani Hospital, Sudan

BMC Research Notes

Ishag Adam⁴  Naji I Ali²  Sumia Z Hamdan⁵  Elhassan M Elhassan¹  Hamdan Z Hamdan⁵  Rihab M Abass³ 

[1] Faculty of Medicine, University of Gezira, Wad Medani, Sudan;Sudan Atomic Energy Commission, Khartoum, Sudan;Sudan Academy of Science, Khartoum, Sudan;Faculty of Medicine, University of Khartoum, P.O. Box 102, Khartoum, Sudan;Faculty of Medicine, Al-Neelain University, P.O. Box 12702, Khartoum, Sudan

关键词: Sudan;    Low birth weight;    Copper;    Zinc;   

Others  :  1132404
DOI  :  10.1186/1756-0500-7-386

 received in 2013-10-28, accepted in 2014-06-16,  发布年份 2014

【 摘 要 】

Background

Low birth weight (LBW) is a worldwide health problem, especially in developing countries. We conducted a case–control study at Medani Hospital, Sudan. Cases were women who delivered a LBW (<2500 g) newborn and consecutive women who delivered a normal weight (>2500 g) newborn were controls. Questionnaires were used to collect clinical data. Zinc and copper levels were measured by an atomic absorption spectrophotometer.

Findings

The two groups (50 in each arm) were well matched in their basic characteristics. Median (25–75th interquartile range) maternal zinc (62.9 [36.3–96.8] vs. 96.2 [84.6–125.7] μg/dl; P <0.001) and copper (81.6 [23.7–167.5] vs. 139.8 [31.9–186.2] μg/dl; P = 0.04) levels were significantly lower in cases than in controls. Cord copper levels in cases were significantly lower than those in controls (108 [55.1–157.9] vs. 147.5 [84.5–185.2] μg/dl; P = 0.02). There were significant direct correlations between birth weight and maternal copper levels and maternal and cord zinc levels.

Conclusions

Maternal zinc and copper levels, as well as cord copper levels, are lower in LBW newborns than in those with normal weight.

【 授权许可】

   
2014 Abass et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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