A phase III randomized three-arm trial of physical therapist delivered pain coping skills training for patients with total knee arthroplasty: the KASTPain protocol

BMC Musculoskeletal Disorders

Kurt Kroenke³  Shelby D Reed²  Matthew J Bair⁴  Mark P Jensen⁷  Levent Dumenci⁸  Khaled J⁶  Dennis Ang¹  Francis J Keefe⁹  Daniel L Riddle⁵ 

[1]Section of Rheumatology, Wake Forest University, Winston-Salem, NC, USA

[2]Duke Clinical Research Institute and Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA

[3]Department of Medicine, Indiana University, Indianapolis, IN, USA

[4]Roudebush VA Medical Center of Excellence on Implementing Evidence-Based Practice, Indianapolis, IN 46202, USA

[5]Departments of Physical Therapy and Orthopaedic Surgery, Virginia Commonwealth University, Richmond, VA, USA

[6]Department of Orthopaedic Surgery, Southern Illinois University, Springfield, IL, USA

[7]Department of Rehabilitation Medicine, University of Washington, Harborview Medical Center, Seattle, WA, USA

[8]Department of Social and Behavioral Health, Virginia Commonwealth University, Richmond, VA, USA

[9]Department of Psychiatry and Behavioral Sciences, Duke Pain Prevention and Treatment Research Program, Duke University, Durham, NC, USA

关键词: Catastrophizing;    Pain;    Coping skills;    Arthroplasty;    Knee;   

Others  :  1145930
DOI  :  10.1186/1471-2474-13-149

 received in 2012-07-25, accepted in 2012-08-15,  发布年份 2012

【 摘 要 】

Background

Approximately 20% of patients report persistent and disabling pain following total knee arthroplasty (TKA) despite an apparently normally functioning prosthesis. One potential risk factor for unexplained persistent pain is high levels of pain catastrophizing. We designed a three-arm trial to determine if a pain coping skills training program, delivered prior to TKA, effectively reduces function-limiting pain following the procedure in patients with high levels of pain catastrophizing.

Methods/design

The trial will be conducted at four University-based sites in the US. A sample of 402 patients with high levels of pain catastrophizing will be randomly assigned to either a pain coping skills training arm, an arthritis education control arm or usual care. Pain coping skills will be delivered by physical therapists trained and supervised by clinical psychologist experts. Arthritis education will be delivered by nurses trained in the delivery of arthritis-related content. The primary outcome will be change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain scale score 12 months following surgery. A variety of secondary clinical and economic outcomes also will be evaluated.

Discussion

The trial will be conducted at four University-based sites in the US. A sample of 402 patients with high levels of pain catastrophizing will be randomly assigned to either a pain coping skills training arm, an arthritis education control arm or usual care. Pain coping skills will be delivered by physical therapists trained and supervised by clinical psychologist experts. Arthritis education will be delivered by nurses trained in the delivery of arthritis-related content. The primary outcome will be change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain scale score 12 months following surgery. A variety of secondary clinical and economic outcomes also will be evaluated.

Trial Registration

NCT01620983

【 授权许可】

   
2012 Riddle et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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