期刊论文详细信息
BMC Medicine
Epidemiology of multimorbidity in China and implications for the healthcare system: cross-sectional survey among 162,464 community household residents in southern China
Stewart W Mercer2  Sian M Griffiths1  Chun Yan Zhu3  Zhi Heng Zhou3  Pei Xi Wang3  Fang Jian Li3  Martin CS Wong1  Samuel YS Wong1  Jia Ji Wang3  Harry HX Wang2 
[1]JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
[2]General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow, 1 Horselethill Road, Glasgow G12 9LX, UK
[3]School of Public Health, Guangzhou Medical University, Guangzhou 510182, P. R. China
关键词: Healthcare;    Population household survey;    Community medicine;    Epidemiology;    Multimorbidity;   
Others  :  1121388
DOI  :  10.1186/s12916-014-0188-0
 received in 2014-06-23, accepted in 2014-09-18,  发布年份 2014
PDF
【 摘 要 】

Background

China, like other countries, is facing a growing burden of chronic disease but the prevalence of multimorbidity and implications for the healthcare system have been little researched. We examined the epidemiology of multimorbidity in southern China in a large representative sample. The effects of multimorbidity and other factors on usual source of healthcare were also examined.

Methods

We conducted a large cross-sectional survey among approximately 5% (N = 162,464) of the resident population in three prefectures in Guangdong province, southern China in 2011. A multistage, stratified random sampling was adopted. The study population had many similar characteristics to the national census population. Interviewer-administered questionnaires were used to collect self-report data on demographics, socio-economics, lifestyles, healthcare use, and health characteristics from paper-based medical reports.

Results

More than one in ten of the total study population (11.1%, 95% confidence interval (CI) 10.6 to 11.6) had two or more chronic conditions from a selection of 40 morbidities. The prevalence of multimorbidity increased with age (adjusted odds ratio (aOR) = 1.36, 95% CI 1.35 to 1.38 per five years). Female gender (aOR = 1.70, 95% CI 1.64 to 1.76), low education (aOR = 1.26, 95% CI 1.23 to 1.29), lack of medical insurance (aOR = 1.79, 95% CI 1.71 to 1.89), and unhealthy lifestyle behaviours were independent predictors of multimorbidity. Multimorbidity was associated with the regular use of secondary outpatient care in preference to primary care.

Conclusions

Multimorbidity is now common in China. The reported preferential use of secondary care over primary care by patients with multimorbidity has many major implications. There is an urgent need to further develop a strong and equitable primary care system.

【 授权许可】

   
2014 Wang et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150212020350540.pdf 1242KB PDF download
Figure 3. 39KB Image download
Figure 2. 30KB Image download
Figure 1. 74KB Image download
【 图 表 】

Figure 1.

Figure 2.

Figure 3.

【 参考文献 】
  • [1]Yang GH, Kong LZ, Zhao WH, Wan X, Zhai Y, Chen LC, Koplan JP: Emergence of chronic non-communicable diseases in China. Lancet 2008, 372:1697-1705.
  • [2]World Health Organization: Preventing Chronic Diseases: A Vital Investment. Geneva, Switzerland: 2005.
  • [3]Fortin M, Bravo G, Hudon C, Vanasse A, Lapointe L: Prevalence of multimorbidity among adults seen in family practice. Ann Fam Med 2005, 3:223-228.
  • [4]Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B: Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet 2012, 380:37-43.
  • [5]Stange KC: In this issue: challenges of managing multimorbidity. Ann Fam Med 2012, 10:2-3.
  • [6]Dawes M: Co-morbidity: we need a guideline for each patient not a guideline for each disease. Fam Pract 2010, 27:1-2.
  • [7]Yip W, Hsiao WC: The Chinese health system at a crossroads. Health Aff (Millwood) 2008, 27:460-468.
  • [8]Gallacher KI, Batty G, McLean G, Mercer SW, Guthrie B, May CR, Langhorne P, Mair FS: Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden. BMC Med 2014, 12:151. BioMed Central Full Text
  • [9]Salisbury C: Multimorbidity: redesigning health care for people who use it. Lancet 2012, 380:7-9.
  • [10]Starfield B, Shi LY, Macinko J: Contribution of primary care to health systems and health. Milbank Q 2005, 83:457-502.
  • [11]Smith JP, Majmundar MK: Aging in Asia: Findings from New and Emerging Data Initiatives. National Academies Press, Washington, D.C; 2012.
  • [12]Chen Z: Launch of the health care reform plan in China. Lancet 2009, 373:1322-1324.
  • [13]Liu Q, Wang B, Kong YY, Cheng KK: China’s primary health-care reform. Lancet 2011, 377:2064-2066.
  • [14]Ministry of Health: Healthy China Plan 2020. Beijing, P. R. China: 2008.
  • [15]State Council: Guidance on Developing Community Health Services in the Cities. No.10 Document. Beijing, P. R. China: 2006.
  • [16]Wang HH, Wang JJ: Developing Primary Care in China. In Routledge Handbook of Global Public Health in Asia. Edited by Griffiths SM, Tang JL, Yeoh EK. Routledge, Oxford, UK; 2014:584-600.
  • [17]Wang HH, Wong SY, Wong MC, Wei XL, Wang JJ, Li DK, Tang JL, Gao GY, Griffiths SM: Patients’ experiences in different models of community health centers in southern China. Ann Fam Med 2013, 11:517-526.
  • [18]Timmins N: The Four UK Health Systems: Learning from Each Other. The King’s Fund, London; 2013.
  • [19]Hu SL, Tang SL, Liu YL, Zhao YX, Escobar ML, de Ferranti D: Reform of how health care is paid for in China: challenges and opportunities. Lancet 2008, 372:1846-1853.
  • [20]Bambra C, Gibson M, Sowden A, Wright K, Whitehead M, Petticrew M: Tackling the wider social determinants of health and health inequalities: evidence from systematic reviews. J Epidemiol Community Health 2010, 64:284-291.
  • [21]Violan C, Foguet-Boreu Q, Flores-Mateo G, Salisbury C, Blom J, Freitag M, Glynn L, Muth C, Valderas JM: Prevalence, determinants and patterns of multimorbidity in primary care: a systematic review of observational studies. PLoS One 2014, 9:e102149.
  • [22]Salisbury C, Johnson L, Purdy S, Valderas JM, Montgomery AA: Epidemiology and impact of multimorbidity in primary care: a retrospective cohort study. Br J Gen Pract 2011, 61:e12-e21.
  • [23]National Bureau of Statistics of China: The Sixth National Population Census. Beijing, P. R. China: 2011.
  • [24]China International Urbanization Development Strategy Research Committee: China Urbanisation Rate Investigation Report. Beijing, P. R. China, 2011.
  • [25]Ministry of Health: China Health Statistics Yearbook. Beijing, P. R. China, 2011.
  • [26]The United Nations Statistics Division: Designing Household Survey Samples: Practical Guidelines, Volume 98. New York, USA, 2008.
  • [27]Center for Health Statistics and Information, Ministry of Health: National Health Services Survey in China. Beijing, P. R. China, 2008.
  • [28]Di Iorio CK: Measurement in Health Behavior: Methods for Research and Education, Volume 1. Jossey-Bass, San Francisco; 2005.
  • [29]Lauritsen JM, Bruus M: EpiData Entry. In A Comprehensive Tool for Validated Entry and Documentation of Data. The EpiData Association, Odense, Denmark; 2008.
  • [30]Diederichs C, Berger K, Bartels DB: The measurement of multiple chronic diseases-a systematic review on existing multimorbidity indices. J Gerontol A Biol Sci Med Sci 2011, 66:301-311.
  • [31]Payne RA, Abel GA, Guthrie B, Mercer SW: The effect of physical multimorbidity, mental health conditions and socioeconomic deprivation on unplanned admissions to hospital: a retrospective cohort study. CMAJ 2013, 185:E221-E228.
  • [32]Huntley AL, Johnson R, Purdy S, Valderas JM, Salisbury C: Measures of multimorbidity and morbidity burden for use in primary care and community settings: a systematic review and guide. Ann Fam Med 2012, 10:134-141.
  • [33]Hunt K, Adamson J, Galdas P: Gender and Help-Seeking: Towards Gender-Comparative Studies. In The Palgrave Handbook of Gender and Healthcare. Edited by Kuhlmann E, Annandale E. Palgrave Macmillan, Basingstoke, UK; 2010:207-222.
  • [34]Malmusi D, Artazcoz L, Benach J, Borrell C: Perception or real illness? How chronic conditions contribute to gender inequalities in self-rated health. Eur J Public Health 2012, 22:781-786.
  • [35]Marengoni A, Angleman S, Melis R, Mangialasche F, Karp A, Garmen A, Meinow B, Fratiglioni L: Aging with multimorbidity: a systematic review of the literature. Ageing Res Rev 2011, 10:430-439.
  • [36]Kaneda T: Chinas Concern over Population Aging and Health. Population Reference Bureau, Washington, DC; 2006.
  • [37]United Nations: Department of Economic: World Population Prospects: The 2004 Revision. Sex and Age Distribution of the World Population. 2nd edition. New York, USA, 2005.
  • [38]Alcorn T: China’s new leaders cut off one-child policy at the root. Lancet 2013, 381:983.
  • [39]Ryan A, Galvin R, Fortin M, Smith SM: Lifestyle Risk Factors and Multimorbidity Risk: A Systematic Review [Research Protocol]. PROSPERO International Prospective Register of Systematic Reviews: PROSPERO 2014. York, UK: CRD42014009593; 2014.
  • [40]Fortin M, Haggerty J, Almirall J, Bouhali T, Sasseville M, Lemieux M: Lifestyle factors and multimorbidity: a cross sectional study. BMC Public Health 2014, 14:686. BioMed Central Full Text
  • [41]Mercer SW, Watt GC: The inverse care law: clinical primary care encounters in deprived and affluent areas of Scotland. Ann Fam Med 2007, 5:503-510.
  • [42]Tang S, Tao J, Bekedam H: Controlling cost escalation of healthcare: making universal health coverage sustainable in China. BMC Public Health 2012, 12:S8. BioMed Central Full Text
  • [43]Li X, Shen JJ, Lu J, Wang Y, Sun M, Li C, Chang F, Hao M: Household catastrophic medical expenses in eastern China: determinants and policy implications. BMC Health Serv Res 2013, 13:506. BioMed Central Full Text
  • [44]Xu Y, Wang L, He J, Bi Y, Li M, Wang T, Jiang Y, Dai M, Lu J, Xu M, Li Y, Hu N, Li J, Mi S, Chen CS, Li G, Mu Y, Zhao J, Kong L, Chen J, Lai S, Wang W, Zhao W, Ning G: Prevalence and control of diabetes in Chinese adults. JAMA 2013, 310:948-959.
  • [45]Ezzati M, Vander Hoorn S, Lawes CM, Leach R, James WP, Lopez AD, Rodgers A, Murray CJ: Rethinking the “diseases of affluence” paradigm: global patterns of nutritional risks in relation to economic development. PLoS Med 2005, 2:e133.
  • [46]Muntner P, Gu D, Wildman RP, Chen J, Qan W, Whelton PK, He J: Prevalence of physical activity among Chinese adults: results from the International Collaborative Study of Cardiovascular Disease in Asia. Am J Public Health 2005, 95:1631-1636.
  • [47]Diamond J: The double puzzle of diabetes. Nature 2003, 423:599-602.
  • [48]Hussey PS, Schneider EC, Rudin RS, Fox DS, Lai J, Pollack CE: Continuity and the costs of care for chronic disease. JAMA Intern Med 2014, 174:742-748.
  • [49]Rasella D, Harhay MO, Pamponet ML, Aquino R, Barreto ML: Impact of primary health care on mortality from heart and cerebrovascular diseases in Brazil: a nationwide analysis of longitudinal data. BMJ 2014, 349:g4014.
  • [50]Wang HH, Wang JJ, Zhou ZH, Wang XW, Xu L: General practice education and training in southern China: recent development and ongoing challenges under the healthcare reform. Malays Fam Physician 2013, 8:2-10.
  • [51]Parry J: GP based primary care is only just starting to emerge in China. Brit Med J 2010, 341:c5049.
  • [52]Schoen C, Osborn R, Squires D, Doty M, Pierson R, Applebaum S: New 2011 survey of patients with complex care needs in eleven countries finds that care is often poorly coordinated. Health Aff (Millwood) 2011, 30:2437-2448.
  • [53]State Council: Guiding Opinions of the State Council About the Pilot Urban Resident Basic Medical Insurance. No. 20 Document. Beijing, P. R. China, 2007.
  • [54]World Health Organization: The World Health Report 2008: Primary Health Care: Now More Than Ever. Geneva, Switzerland, 2008.
  文献评价指标  
  下载次数:23次 浏览次数:8次