BMC Geriatrics | |
Development and use of a computer program to detect potentially inappropriate prescribing in older adults residing in Canadian long-term care facilities | |
Norman Flett7  George Heckman4  Nicole Ferko3  Sacha Dubois1  Glenda Campbell6  Michel Bedard2  Alexandra Papaioannou5  | |
[1] Department of Clinical Epidemiology and Biostatistics, McMaster University Hamilton, Ontario, Canada;Lakehead Psychiatric Hospital, Thunderbay, Ontario, Canada;Department of Clinical Health Sciences, McMaster University Hamilton, Ontario, Canada;Department of Medicine, McMaster University Hamilton, Ontario, Canada;Division of Geriatric Medicine, McMaster University Hamilton, Ontario, Canada;Medical Pharmacies Ltd. Pickering Ontario, Canada;St. Joseph's Villa Dundas, Ontario, Canada | |
关键词: elderly; computer program; drug database; long-term care; inappropriate prescribing; | |
Others : 858642 DOI : 10.1186/1471-2318-2-5 |
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received in 2002-07-04, accepted in 2002-10-14, 发布年份 2002 | |
【 摘 要 】
Background
Inappropriate prescribing has been estimated to be as high as 40% in long-term care. The purpose of this study was to develop a computer program that identifies potentially inappropriate drug prescriptions and to test its reliability.
Methods
Potentially inappropriate prescriptions were identified based on modified McLeod guidelines. A database from one pharmacy servicing long-term care facilities in Ontario was utilized for this cross-sectional study. Prescription information was available for the 356 long-term care residents and included: the date the prescription was filled, the quantity of drug prescribed and the eight-digit drug identification number. The pharmacy database was linked to the computer-based program for targeting potential inappropriate prescriptions. The computer program's reliability was assessed by comparing its results to a manual search conducted by two independent research assistants.
Results
There was complete agreement between the computer and manual abstraction for the total number of potentially inappropriate prescriptions detected. In total, 83 potentially inappropriate prescriptions were identified. Fifty-three residents (14.9%) received at least one potentially inappropriate prescription. Of those, twenty (37.7%) received two potential inappropriate prescriptions and eight (15.1%) received 3 or more potential inappropriate prescriptions. The most common potential inappropriate prescriptions were identified as long-term use of non-steroidal anti-inflammatory agents and tricyclic antidepressants with active metabolites.
Conclusion
A computer program can accurately and automatically detect inappropriate prescribing in residents of long-term care facilities. This tool may be used to identify potentially inappropriate drug combinations and educate health care professionals.
【 授权许可】
2002 Papaioannou et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
【 预 览 】
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【 参考文献 】
- [1]National Institute on Aging, US Department of Commerce, Economics and Statistics Administration, Bureau of the Census: Aging in the United States: past, present, future. Washington 1997.
- [2]Chrischilles EA, Foley DJ, Wallace RB, Lemke JH, Semla TP, Hanlon JT, Glynn RJ, Ostfeld AM, Guralnik JM: Use of medications by persons 65 and over: data from the established populations for epidemiologic studies of the elderly. J Gerontol A Biol Sci Med Sci 1992, 47:M137-144.
- [3]Ouslander JG: Medical care in the nursing home. JAMA 1989, 262(18):2582-2590.
- [4]Dhall J, Larrat EP, Lapane KL: Use of potentially inappropriate drugs in nursing homes. Pharmacotherapy 2002, 22(1):88-96.
- [5]Piecoro LT, Browning SR, Prince TS, Ranz TT, Scutchfield FD: A database analysis of potentially inappropriate drug use in an elderly medicaid population. Pharmacotherapy 2000, 20(2):221-228.
- [6]Beers MH, Ouslander JG, Fingold SF, Morgenstern H, Reuben DB, Rogers W, Zeffren MJ, Beck JC: Inappropriate medication prescribing in skilled nursing facilities. Ann Intern Med 1992, 117:684-689.
- [7]Avorn J, Gurwitz JH: The ambiguous relationship between age and adverse drug reactions. Ann Intern Med 1991, 114:956-966.
- [8]Schmader KE, Hanlon JT, Landsman PB, Samsa GP, Lewis IK, Weinberger M: Inappropriate prescribing and health outcomes in elderly veteran outpatients. Ann Pharmacother 1997, 31:529-533.
- [9]Tafreshi MJ, Melby MJ, Kaback KR, Nord TC: Medication-related visits to the emergency department: a prospective study. Ann Pharmacother 1999, 33(12):1252-1257.
- [10]Rochon PA, Gurwitz JH: Optimizing drug treatment for elderly people: the prescribing cascade. BMJ 1997, 315(7115):1096-1099.
- [11]McLeod PJ, Huang AR, Tamblyn RM, Gayton DC: Defining inappropriate practices in prescribing for elderly people: a national consensus panel. Can Med Assoc J 1997, 156(3):385-391.
- [12]Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC: Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Intern Med 1991, 151:1825-1832.
- [13]Beers MH: Explicit criteria for determining potentially inappropriate medication use by the elderly: an update. Arch Intern Med 1997, 157:1531-1536.
- [14]Naugler CT, Brymer C, Stolee P, Arcese ZA: Development and validation of an improving prescribing in the elderly tool. Can J Clin Pharmacol 2000, 7(2):103-107.
- [15]Gill SS, Misiaszek BC, Brymer C: Improving prescribing in the elderly: a study in the long term care setting. Can J Clin Pharmacol 2001, 8(2):78-83.
- [16]Walton R, Dovey S, Harvey E, Freemantle N: Computer support for determining drug dose: systematic review and meta-analysis. BMJ 1999, 318(7189):984-990.
- [17]McMullin ST, Reichley RM, Kahn MG, Claiborne KW, Bailey TC: Automated system for identifying potential dosage problems at a large university hospital. Am J Health Syst Pharm 1997, 54:545-549.
- [18]Goldberg DE, Baardsgaard G, Johnson MT, Jolowsky CM, Shepherd M, Peterson CD: Computer-based program for identifying medication orders requiring dosage modification based on renal function. Am J Health Syst Pharm 1991, 48:1965.
- [19]Hirsh J: Guidelines for Antithrombotic Therapy. BC Decker Inc. 3rd edition. 1991, 11:40.
- [20]Hogan DB, Ebly EM, Fung TS: Regional variations in use of potentially inappropriate medication by Canadian seniors participating in the Canadian Study of Health and Aging. Can J Clin Pharmacol 1995, 2(4):167-174.
- [21]Tamblyn RM, McLeod PJ, Abrahamowicz M, Laprise R: Do too many cooks spoil the broth? Multiple physician involvement in medical management of elderly patients and potentially inappropriate drug combinations. Can Med Assoc J 1996, 154(8):1177-1183.
- [22]Beers MH, Fingold SF, Ouslander JG: A computerized system for identifying and informing physicians about problematic drug use in nursing homes. J Med Syst 1992, 16(6):237-245.
- [23]Stein MC, Griffin MR, Taylor JA, Pichert JW, Brandt KD, Ray WA: Educational program for nursing home physicians and staff to reduce use of non-steroidal anti-inflammatory drugs among nursing home residents. Medical Care 2001, 39(5):436-445.
- [24]Aparasu RR, Mort JR: Inappropriate prescribing for the elderly: beers criteria-based review. Ann Pharmacother 2000, 34(3):338-46.
- [25]Ballard C, O'Brien J, James I, Mynt P, Lana M, Potkins D, Reichelt K, Lee L, Swann A, Fossey J: Quality of life for people with dementia living in residential and nursing home care: the impact of performance on activities of daily living, behavioural and psychological symptoms, language skills, and psychotropic drug use. Int Psychogeriatrics 2001, 13(1):93-106.
- [26]McGrath AM, Jackson GA: Survey of neuroleptic prescribing in residents of nursing homes in Glasgow. BMJ 1996, 312:611-612.