BMC Medicine | |
Integrated care as a means to improve primary care delivery for adults and adolescents in the developing world: a critical analysis of Integrated Management of Adolescent and Adult Illness (IMAI) | |
Paul E Farmer5  David C Mabey1  Kwonjune Seung5  Tom Nicholson2  Peter Drobac5  Neil Gupta5  Manzi Anatole2  Sandy Gove4  Stephen D Lawn1  Andrew Ellner5  Ashwin Vasan3  | |
[1] Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK;Partners In Health, Kigali, Rwanda;Department of Medicine, Weill Cornell Medical College/New York-Presbyterian Hospital, New York, NY, USA;IMAI-IMCI Alliance, San Francisco, CA, USA;Division of Global Health Equity, Brigham & Women’s Hospital, Boston, MA, USA | |
关键词: IMAI; Health systems; Health care delivery; Quality improvement; Integration; Integrated management; Primary care; | |
Others : 855169 DOI : 10.1186/1741-7015-12-6 |
|
received in 2013-08-30, accepted in 2013-12-17, 发布年份 2014 | |
【 摘 要 】
Background
More than three decades after the 1978 Declaration of Alma-Ata enshrined the goal of ‘health for all’, high-quality primary care services remain undelivered to the great majority of the world’s poor. This failure to effectively reach the most vulnerable populations has been, in part, a failure to develop and implement appropriate and effective primary care delivery models. This paper examines a root cause of these failures, namely that the inability to achieve clear and practical consensus around the scope and aims of primary care may be contributing to ongoing operational inertia. The present work also examines integrated models of care as a strategy to move beyond conceptual dissonance in primary care and toward implementation. Finally, this paper examines the strengths and weaknesses of a particular model, the World Health Organization’s Integrated Management of Adolescent and Adult Illness (IMAI), and its potential as a guidepost toward improving the quality of primary care delivery in poor settings.
Discussion
Integration and integrated care may be an important approach in establishing a new paradigm of primary care delivery, though overall, current evidence is mixed. However, a number of successful specific examples illustrate the potential for clinical and service integration to positively impact patient care in primary care settings. One example deserving of further examination is the IMAI, developed by the World Health Organization as an operational model that integrates discrete vertical interventions into a comprehensive delivery system encompassing triage and screening, basic acute and chronic disease care, basic prevention and treatment services, and follow-up and referral guidelines. IMAI is an integrated model delivered at a single point-of-care using a standard approach to each patient based on the universal patient history and physical examination. The evidence base on IMAI is currently weak, but whether or not IMAI itself ultimately proves useful in advancing primary care delivery, it is these principles that should serve as the basis for developing a standard of integrated primary care delivery for adults and adolescents that can serve as the foundation for ongoing quality improvement.
Summary
As integrated primary care is the standard of care in the developed world, so too must we move toward implementing integrated models of primary care delivery in poorer settings. Models such as IMAI are an important first step in this evolution. A robust and sustained commitment to innovation, research and quality improvement will be required if integrated primary care delivery is to become a reality in developing world.
【 授权许可】
2014 Vasan et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20140722030937490.pdf | 4556KB | download |
【 参考文献 】
- [1]WHO: Declaration of Alma-Ata: international conference on primary health care. [http://www.who.int/publications/almaata_declaration_en.pdf webcite]
- [2]Magnussen L, Ehiri J, Jolly P: Comprehensive versus selective primary health care: lessons for global health. Health Aff 2004, 23:167-176.
- [3]Sanders D, Schaay N, Mohamed S: Primary health care. In International Encyclopedia of Public Health, Volume 5. Edited by Heggenhougen K, Quah S. San Diego, CA: Academic Press; 2008:305-316.
- [4]Chan M: Return to Alma-Ata. Lancet. 2008, 372:865-866.
- [5]Bhatia M, Rifkin S: A renewed focus on primary health care: revitalize or reframe? Global Health 2010, 6:13.
- [6]Kruk ME, Porignon D, Rockers PC, Van Lerberghe W: The contribution of primary health to health and health systems in low- and middle-income countries: a critical review of major primary care initiatives. Soc Sci Med 2010, 70:904-911.
- [7]Rohde J, Cousens S, Chopra M, Tangcharoensathien V, Black R, Bhutta ZA, Lawn JE: 30 years after Alma-Ata has primary care worked in countries? Lancet 2008, 372:950-961.
- [8]Lewin S, Lavis JN, Oxman AD, Bastías G, Chopra M, Ciapponi A, Flottorp S, Martí SG, Pantoja T, Rada G, Souza N, Treweek S, Wiysonge CS, Haines A: Supporting the delivery of cost-effective interventions in primary health-care systems in low-income and middle-income countries: an overview of systematic reviews. Lancet 2008, 372:928-939.
- [9]Lawn JE, Rhode J, Rifkin S, Were M, Paul VK, Chopra M: Alma-Ata 30 years on: revolutionary, relevant, and time to revitalize. Lancet 2008, 372:917-927.
- [10]WHO: Maximizing positive synergies between health systems and Global Health Initiatives. [http://www.who.int/healthsystems/GHIsynergies/en/ webcite]
- [11]Samb B, Evans T, Dybul M, Atun R, Moatti JP, Nishtar S, Wright A, Celletti F, Hsu J, Kim JY, Brugha R, Russell A, Etienne C, World Health Organization Maximizing Positive Synergies Collaborative Group: An assessment of interactions between global health initiatives and country health systems. Lancet 2009, 373:2137-2169.
- [12]WHO: The World Health Report 2006 - Working Together For Health. Geneva, Switzerland: World Health Organization; 2006.
- [13]Narasimhan V, Brown H, Pablos-Mendez A, Adams O, Dussault G, Elzinga G, Nordstrom A, Habte D, Jacobs M, Solimano G, Sewankambo N, Wibulpolprasert S, Evans T, Chen L: Responding to the global human resources crisis. Lancet 2004, 363:1469-1472.
- [14]Muldoon LK, Hogg WE, Levitt M: Primary care (PC) and primary health care (PHC). What is the difference? Can J Public Health 2006, 97:409-411.
- [15]Starfield B: Politics, primary healthcare and health: was Virchow right? J Epidemiol Community Health 2011, 65:653-655.
- [16]Starfield B, Shi L, Macinko J: Contribution of primary care to health systems and health. Milbank Q 2005, 83:457-502.
- [17]Frenk J: Reinventing primary care: the need for systems integration. Lancet 2009, 374:170-173.
- [18]Frenk J, Gonzalez-Block MA, Alvarez-Manilla JM: First contact, simplified technology, or risk anticipation? Defining primary health care. Acad Med 1990, 65:676-681.
- [19]Starfield B, Shi L: Policy relevant determinants of health: an international perspective. Health Policy 2002, 60:201-218.
- [20]Gilson L, Doherty J, Loewenson R, Francis V, and Members of the Health Systems Knowledge Network: Challenging Inequity through Health Systems. Final Report, WHO Commission on the Social Determinants of Health. [http://www.who.int/social_determinants/resources/csdh_media/hskn_final_2007_en.pdf webcite]
- [21]Friedberg MW, Hussey PS, Schneider EC: Primary care: a critical review of the evidence on quality and costs of health care. Health Aff 2010, 29:766-772.
- [22]Walsh JA, Warren KS: Selective primary health care: an interim strategy for disease control in developing countries. N Engl J Med 1979, 301:967-974.
- [23]The Lancet Editorial Board: A renaissance in primary health care. Lancet 2008, 372:863.
- [24]Walley J, Lawn JE, Tinker A, de Francisco A, Chopra M, Rudan I, Bhutta ZA, Black RE, Lancet Alma-Ata Working Group: Primary health care: making Alma-Ata a reality. Lancet 2008, 372:1001-1007.
- [25]Walton DA, Farmer PE, Lambert W, Leandre F, Koenig SP, Mukherjee JS: Integrated HIV prevention and care strengthens primary health care: Lessons from rural Haiti. J Public Health Policy 2004, 25:137-158.
- [26]Koenig SP, Léandre F, Farmer PE: Scaling-up HIV treatment programmes in resource-limited settings: the rural Haiti experience. AIDS 2004, 18:S21-S25.
- [27]Mukherjee J, Colas M, Farmer P, Léandre F, Lambert W, Raymonville M, Koenig S, Walton D, Névil P, Louissant N, Cynthia Orélus C: Access to antiretroviral treatment and care: the experience of the HIV Equity Initiative, Cange, Haiti, Case study: Perspectives and Practice in Antiretroviral Treatment. [http://www.who.int/hiv/pub/prev_care/en/Haiti_E.pdf webcite]
- [28]Coovadia H, Bland R: From Alma-Ata to Agincourt: primary care in AIDS. Lancet 2008, 372:866-867.
- [29]Phiri S, Khan PY, Grant AD, Gareta D, Tweya H, Kalulu M, Chaweza T, Mbetewa L, Kanyerere H, Weigel R, Feldacker C: Integrated tuberculosis and HIV care in a resource-limited setting: experience from the Martin Preuss centre, Malawi. Trop Med Int Health 2011, 16:1397-1403.
- [30]Harris JB, Hatwiinda SM, Randels KM, Chi BH, Kancheya NG, Jham MA, Samungole KV, Tambatamba BC, Cantrell RA, Levy JW, Kimerling ME, Reid SE: Early lessons from the integration of tuberculosis and HIV services in primary care centers in Lusaka, Zambia. Int J Tuberc Lung Dis 2008, 12:773-779.
- [31]Ansa GA, Walley JD, Siddiqi K, Wei X: Assessing the impact of TB/HIV services integration on TB treatment outcomes and their relevance in TB/HIV monitoring in Ghana. Infect Dis Poverty 2012, 1:13. BioMed Central Full Text
- [32]Legido-Quigley H, Montgomery CM, Khan P, Atun R, Fakoya A, Getahun H, Grant AD: Integrating tuberculosis and HIV services in low- and middle-income countries: a systematic review. Trop Med Int Health 2013, 18:199-211.
- [33]Tudor Car L, Van Velthoven MH, Brusamento S, Elmoniry H, Car J, Majeed A, Atun R: Integrating prevention of mother-to-child HIV transmission programs to improve uptake: a systematic review. PLoS One 2012, 7:e35268.
- [34]Church K, Mayhew SH: Integration of STI and HIV prevention, care, and treatment into family planning services: a review of the literature. Stud Fam Plann 2009, 40:171-186.
- [35]Kennedy C, Spaulding A, Brickley D, Almers L, Mirjahangir J, Packel L, Almers L, Mirjahangir J, Packel L, Kennedy GE, Mbizvo M, Collins L, Osborne K: Linking sexual and reproductive health and HIV interventions: a systematic review. J Int AIDS Soc 2010, 13:26. BioMed Central Full Text
- [36]Huntington D, Aplogan A: The integration of family planning and childhood immunization services in Togo. Stud Fam Plann 1995, 25:176083.
- [37]Price JE, Leslie JA, Welsh M, Binagwaho A: Integrating HIV clinical services into primary health care in Rwanda: a measure of quantitative effects. AIDS Care 2009, 21:608-614.
- [38]Peck R, Fitzgerald DW, Liautaud B, Deschamps MM, Verdier RI, Beaulieu ME, Grand Pierre R, Joseph P, Severe P, Noel F, Wright P, Johnson WD Jr, Pape JW: The feasibility, demand, and effect of integrating primary care services with HIV voluntary counseling and testing: evaluation of a 15-year experience in Haiti, 1985–2000. J Acquir Immune Defic Syndr 2003, 33:470-475.
- [39]Dudley L, Garner P: Strategies for integrating primary health services in low- and middle-income countries at the point of delivery. Cochrane Database Syst Rev 2011., 7CD003318
- [40]Briggs CJ, Garner P: Strategies for integrating primary health services in middle- and low-income countries at the point of delivery. Cochrane Database Syst Rev 2006., 2CD003318
- [41]Briggs CJ, Capdegelle P, Garner P: Strategies for integrating primary health services in middle- and low-income countries: effects on performance, costs and patient outcomes. Cochrane Database Syst Rev 2001., 4CD003318
- [42]English RG, Bateman ED, Zwarenstein MF, Fairall LR, Bheekie A, Bachmann MO, Majara B, Ottmani SE, Scherpbier RW: Development of a South African integrated syndromic respiratory disease guideline for primary care. Prim Care Respir J 2008, 17:156-163.
- [43]Bheekie A, Buskens I, Allen S, English R, Mayers P, Fairall L, Majara B, Bateman ED, Zwarenstein M, Bachmann M: The Practical Approach to Lung Health in South Africa (PALSA) intervention: respiratory guideline implementation for nurse trainers. Int Nurs Rev 2006, 53:261-268.
- [44]Stein J, Lewin S, Fairall L, Mayers P, English R, Bheekie A, Bateman E, Zwarenstein M: Building capacity for antiretroviral delivery in South Africa: a qualitative evaluation of the PALSA PLUS nurse training programme. BMC Health Serv Res 2008, 8:240. BioMed Central Full Text
- [45]Schull MJ, Banda H, Kathyola D, Fairall L, Martiniuk A, Burciul B, Zwarenstein M, Sodhi S, Thompson S, Joshua M, Mondiwa M, Bateman E: Strengthening health human resources and improving clinical outcomes through an integrated guideline and educational outreach in resource-poor settings: a cluster-randomized trial. Trials 2010, 11:118. BioMed Central Full Text
- [46]Schull MJ, Cornick R, Thompson S, Faris G, Fairall L, Burciul B, Sodhi S, Draper B, Joshua M, Mondiwa M, Banda H, Kathyola D, Bateman E, Zwarenstein M: From PALSA PLUS to PALM PLUS: adapting and developing a South African guideline and training intervention to better integrate HIV/AIDS care with primary care in rural health centers in Malawi. Implement Sci 2011, 6:82. BioMed Central Full Text
- [47]Zwarenstein M, Fairall LR, Lombard C, Mayers P, Bheekie A, English RG, Lewin S, Bachmann MO, Bateman E: Outreach education for integration of HIV/AIDS care, antiretroviral treatment, and tuberculosis care in primary care clinics in South Africa: PALSA PLUS pragmatic cluster randomised trial. BMJ 2011, 342:d2022.
- [48]Sodhi S, Banda H, Kathyola D, Burciul B, Thompson S, Joshua M, Bateman E, Fairall L, Martiniuk A, Cornick R, Faris G, Draper B, Mondiwa M, Katengeza E, Sanudi L, Zwarenstein M, Schull MJ: Evaluating a streamlined clinical tool and educational outreach intervention for health care workers in Malawi: the PALM PLUS case study. BMC Int Health Hum Rights 2011, 11:S11.
- [49]Fairall L, Bachmann MO, Zwarenstein M, Bateman ED, Niessen LW, Lombard C, Majara B, English R, Bheekie A, van Rensburg D, Mayers P, Peters A, Chapman R: Cost-effectiveness of educational outreach to primary care nurses to increase tuberculosis case detection and improve respiratory care: economic evaluation alongside a randomized trial. Trop Med Int Health 2010, 15:277-286.
- [50]Chowdhury EK, El Arifeen S, Rahman M, Hoque DE, Hossain MA, Begum K, Siddik A, Begum N, Sadeq-ur Rahman Q, Akter T, Haque TM, Al-Helal ZM, Baqui AH, Bryce J, Black RE: Care at first-level facilities for children with severe pneumonia in Bangladesh: a cohort study. Lancet 2008, 372:822-830.
- [51]Armstrong-Schellenberg JR, Adam T, Mshinda H, Masanja H, Kabadi G, Mukasa O, John T, Charles S, Nathan R, Wilczynska K, Mgalula L, Mbuya C, Mswia R, Manzi F, de Savigny D, Schellenberg D, Victora C: Effectiveness and cost of facility-based Integrated Management of Childhood Illness (IMCI) in Tanzania. Lancet 2004, 364:1583-1594.
- [52]Arifeen SE, Hoque DM, Akter T, Rahman M, Hoque ME, Begum K, Chowdhury EK, Khan R, Blum LS, Ahmed S, Hossain MA, Siddik A, Begum N, Sadeq-urRahman Q, Haque TM, Billah SM, Islam M, Rumi RA, Law E, Al-Helal ZA, Baqui AH, Schellenberg J, Adam T, Moulton LH, Habicht JP, Scherpbier RW, Victora CG, Bryce J, Black RE: Effect of the Integrated Management of Childhood Illness strategy on childhood mortality and nutrition in a rural area in Bangladesh: a cluster randomised trial. Lancet 2009, 374:393-403.
- [53]Bryce J, Victora CG, Habicht JP, Black RE, Scherpbier RW, Technical MCE-IMCI, MCE-IMCI Technical Advisors: Programmatic pathways to child survival: results of a multi-country evaluation of Integrated Management of Childhood Illness. Health Policy Plan 2005, 20:i5-i17.
- [54]Duke T: Child survival and IMCI: in need of sustained global support. Lancet 2009, 374:361-362.
- [55]Rakha MA, Abdelmoneim AN, Farhoud S, Pièche S, Cousens S, Daelmans B, Bahl R: Does implementation of the IMCI strategy have an impact on child mortality? A retrospective analysis of routine data from Egypt. BMJ Open 2013, 3:e001852.
- [56]Mosquera PA, Hernández J, Vega R, Martínez J, Sebastián MS: Performance evaluation of the essential dimensions of the primary health care services in six localities of Bogota–Colombia: a cross-sectional study. BMC Health Serv Res 2013, 13:315. BioMed Central Full Text
- [57]Sherr K, Cuembelo F, Michel C, Gimbel S, Micek M, Kariaganis M, Pio A, Manuel JL, Pfeiffer J, Gloyd S: Strengthening integrated primary health care in Sofala. Mozambique. BMC Health Serv Res 2013, 13:S4.
- [58]World Health Organization: IMAI/IMCI heath centre/primary care guideline modules. http://www.who.int/hiv/pub/imai/primary_acute/en/index.html webcite
- [59]World Health Organization: IMAI Chronic HIV Care with ARV Therapy and Prevention. http://www.who.int/hiv/pub/imai/primary_arv/en/index.html webcite
- [60]World Health Organization, HIV/AIDS Programme: Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach. http://www.who.int/hiv/pub/arv/adult2010/en/index.html webcite
- [61]Vitoria M, Vella S, Ford N: Scaling up antiretroviral therapy in resource-limited settings: adapting guidance to meet the challenges. Curr Opin HIV AIDS 2013, 8:12-18.
- [62]Vasan A, Kenya-Mugisha N, Seung KJ, Achieng M, Banura P, Lule F, Beems M, Todd J, Madraa E: Agreement between physicians and non-physician clinicians in starting antiretroviral therapy in rural Uganda. Hum Resour Health 2009, 7:75. BioMed Central Full Text
- [63]Clark G, Chapman Y, Francis K: Surveying health professionals’ satisfaction with the Integrated Management of Adult and Adolescent Illness Chronic HIV Care training programme: the Papua New Guinea experience. Int J Nurs Pract 2009, 15:519-524.
- [64]Woldie M, Enquselassie F: Assessment of the validity of the guideline for integrated management of adult and adolescent illnesses on HIV patients in Addis Ababa, Ethiopia. Ethiop Med J 2009, 47:195-203.
- [65]Awoonor-Williams JK, Bawah AA, Nyonator FK, Asuru R, Oduro A, Ofosu A, Phillips JF: The Ghana essential health interventions program: a plausibility trial of the impact of health systems strengthening on maternal & child survival. BMC Health Serv Res 2013, 13:S3. BioMed Central Full Text
- [66]Drobac PC, Basinga P, Condo J, Farmer PE, Finnegan KE, Hamon JK, Amoroso C, Hirschhorn LR, Kakoma JB, Lu C, Murangwa Y, Murray M, Ngabo F, Rich M, Thomson D, Binagwaho A: Comprehensive and integrated district health systems strengthening: the Rwanda Population Health Implementation and Training (PHIT) Partnership. BMC Health Serv Res 2013, 13:S5. BioMed Central Full Text
- [67]Lassi ZS, Haider BA, Bhutta ZA: Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes. Cochrane Database Syst Rev 2010., 11CD007754
- [68]Klein SJ, Naizby BE: Creation of a tuberculosis directly observed therapy provider network in New York City: a new model of public health. J Public Health Manag Pract 1995, 1:1-6.
- [69]Floyd K, Wilkinson D, Gilks C: Comparison of cost effectiveness of directly observed treatment (DOT) and conventionally delivered treatment for tuberculosis: experience from rural South Africa. BMJ 1997, 315:1407-1411.
- [70]Farmer P, Léandre F, Mukherjee J, Gupta R, Tarter L, Kim JY: Community-based treatment of advanced HIV disease: introducing DOT-HAART (directly observed therapy with highly active antiretroviral therapy). Bull World Health Organ 2001, 79:1145-1151.
- [71]Shin S, Furin J, Bayona J, Mate K, Kim JY, Farmer P: Community-based treatment of multidrug-resistant tuberculosis in Lima, Peru: 7 years of experience. Soc Sci Med 2004, 59:1529-1539.
- [72]Bemelmans M, Van Den Akker T, Ford N, Philips M, Zachariah R, Harries A, Schouten E, Hermann K, Mwagomba B, Massaquoi M: Providing universal access to antiretroviral therapy in Thyolo, Malawi through task shifting and decentralization of HIV/AIDS care. Trop Med Int Health 2010, 15:1413-1420.
- [73]Selke HM, Kimaiyo S, Sidle JE, Vedanthan R, Tierney WM, Shen C, Denski CD, Katschke AR, Wools-Kaloustian K: Task-shifting of antiretroviral delivery from health care workers to persons living with HIV/AIDS: clinical outcomes of a community-based program in Kenya. J Acquir Immune DeficSyndr 2010, 55:483-490.
- [74]Celletti F, Wright A, Palen J, Frehywot S, Markus A, Greenberg A, de Aguiar RA, Campos F, Buch E, Samb B: Can the deployment of community health workers for the delivery of HIV services represent an effective and sustainable response to health workforce shortages? Results of a multicountry study. AIDS 2010, 24:S45-S57.
- [75]Hermann K, Van Damme W, Pariyo GW, Schouten E, Assefa Y, Cirera A, Massavon W: Community health workers for ART in sub-Saharan Africa: learning from experience–capitalizing on new opportunities. Hum Resour Health 2009, 7:31. BioMed Central Full Text
- [76]Beaglehole R, Yach D: Globalisation and the prevention and control of non-communicable disease: the neglected chronic diseases of adults. Lancet 2003, 362:903-908.
- [77]Singh P, Sachs JD: 1 Million community health workers in sub-Saharan Africa by 2015. Lancet 2013, 382:363-365.
- [78]Vasan A, Ellner A, Lawn SD, Gupta N, Anatole M, Drobac P, Nicholson T, Gove S, Seung K, Mabey D, Farmer P: Strengthening of primary-care delivery in the developing world: IMAI and the need for integrated models of care. Lancet Global Health 2013, 1:e321-e323.
- [79]Marais BJ, Lönnroth K, Lawn SD, Migliori GB, Mwaba P, Glaziou P, Bates M, Colagiuri R, Zijenah L, Swaminathan S, Memish ZA, Pletschette M, Hoelscher M, Abubakar I, Hasan R, Zafar A, Pantaleo G, Craig G, Kim P, Maeurer M, Schito M, Zumla A: Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts. Lancet Infect Dis 2013, 13:436-448.
- [80]Atun R, Weil DEC, Eang MT, Mwakuysa D: Health-system strengthening and tuberculosis control. Lancet 2010, 375:2169-2178.
- [81]Sweeney S, Dayo C, Obure C, Maier CB, Greener R, Dehne K, Vassall A: Costs and efficiency of integrating HIV/AIDS services with other health services: a systematic review of evidence and experience. Sex Transm Infect 2012, 88:85-99.
- [82]Maina WK: Integrating noncommunicable disease prevention into maternal and child health programs: can it be done and what will it take? Int J Gynaecol Obstet 2011, 115:S34-S36.
- [83]World Health Organization: Community-Directed Interventions for Major Health Problems in Africa: A Multi-Country Study: Final Report, WHO special programme for research and training in tropical diseases. Geneva, Switzerland: World Health Organization; 2008.
- [84]World Health Organization: General Principles of Good Chronic Care: Integrated Management of Adolescent and Adult Illness. http://www.who.int/hiv/pub/imai/generalprinciples082004.pdf webcite
- [85]Vasan A, Anatole M, Mezzacappa C, Hedt-Gauthier BL, Hirschhorn LR, Nkikabahizi F, Hagenimana M, Ndayisaba A, Cyamatare FR, Nzeyimana B, Drobac P, Gupta N: Baseline assessment of adult and adolescent primary care delivery in Rwanda: an opportunity for quality improvement. BMC Health Serv Res 2013, 13:518. BioMed Central Full Text
- [86]Anatole M, Magge H, Redditt V, Niyonzima S, Drobac P, Mukherjee JS, Ntaganira J, Nyirazinyoye L, Hirschhorn LR: Nurse mentorship to improve the quality of health care delivery in rural Rwanda. Nurs Outlook 2013, 61:137-144.
- [87]Weber MW, Mulholland ED, Jaffar S, Troedsson H, Gove S, Greenwood BM: Evaluation of an algorithm for the integrated management of childhood illness in an area with seasonal malaria in the Gambia. Bull World Health Organ 1997, 75:25-32.
- [88]Perkins BA, Zucker JR, Otieno J, Jafari HS, Paxton L, Redd SC, Nahlen BL, Schwartz B, Oloo AJ, Olango C, Gove S, Campbell CC: Evaluation of an algorithm for integrated management of childhood illness in an area of Kenya with high malaria transmission. Bull World Health Organ 1997, 75:33-42.
- [89]Kolstad PR, Burnham G, Kalter HD, Kenya-Mugisha N, Black RE: The integrated management of childhood illness in western Uganda. Bull World Health Organ 1997, 75:77-85.
- [90]Kalter HD, Burnham G, Kolstad PR, Hossain M, Schillinger JA, Khan NZ, Saha S, de Wit V, Kenya-Mugisha N, Schwartz B, Black RE: Evaluation of clinical signs to diagnose anemia in Uganda and Bangladesh, in areas with and without malaria. Bull World Health Organ 1997, 75:103-111.
- [91]Shah D, Sachdev HP: Evaluation of the WHO/UNICEF algorithm for integrated management of childhood illness between the age of two months to five years. Indian Pediatr 1999, 36:767-777.
- [92]Mogensen CB, Soerensen J, Bjorkman A, Montgomery SM: Algorithms for the diagnosis of anaemia without laboratory facilities among small children in a malaria endemic area of rural Tanzania. Acta Trop 2006, 99:119-125.
- [93]Simoes EA, Desta T, Tessema T, Gerbresellassie T, Dagnew M, Gove S: Performance of health worker after training in integrated management of childhood illness in Gondar, Ethiopia. Bull World Health Organ 1997, 75:43-53.
- [94]Kahigwa E, Schellenberg D, Schellenberg JA, Aponte JJ, Alonso PL, Menendez C: Inter-observer agreement in the assessment of clinical signs in sick Tanzanian children. Trans R Soc Trop Med Hyg 2002, 96:162-166.