期刊论文详细信息
BMC Infectious Diseases
Seroepidemiology of cytomegalovirus infection in pregnant women in Durango City, Mexico
Carlos Alberto Guido-Arreola1  Alma Rosa Pérez-Álamos3  Lucio Martínez-Ramírez1  Sergio Estrada-Martínez3  Sandra Margarita Cerrillo-Soto1  Agar Ramos-Nevárez1  Luis Francisco Sánchez-Anguiano3  Jesús Hernández-Tinoco3  Cosme Alvarado-Esquivel2 
[1] Clínica de Medicina Familiar, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Predio Canoas S/N, 34079 Durango, Mexico;Biomedical Research Laboratory, Faculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico;Institute for Scientific Research “Dr. Roberto Rivera-Damm”, Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico
关键词: Mexico;    Epidemiology;    Infection;    Cytomegalovirus;    Seroprevalence;    Cross-sectional study;   
Others  :  1125649
DOI  :  10.1186/1471-2334-14-484
 received in 2014-07-05, accepted in 2014-09-03,  发布年份 2014
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【 摘 要 】

Background

Cytomegalovirus causes congenital infections all around the world. The seroepidemiology of cytomegalovirus infection in pregnant women in Mexico is largely unknown. We sought to determine the seroprevalence of cytomegalovirus infection in pregnant women in Durango City, Mexico; and to determine seroprevalence association with socio-demographic, clinical and behavioral characteristics of pregnant women.

Methods

Through a cross-sectional study design, 343 pregnant women were examined for anti-cytomegalovirus IgG and IgM antibodies in Durango City, Mexico. We used a standardized questionnaire to obtain the general characteristics of the pregnant women. Multivariate analysis was performed to determine the association of cytomegalovirus infection with the characteristics of the pregnant women.

Results

Anti-CMV IgG and IgM antibodies were detected in 225 (65.6%) and in none of the 343 pregnant women studied, respectively. Multivariate analysis showed that CMV exposure was associated with increasing age (OR = 1.67; 95% CI: 1.01-2.76; P = 0.04). Other women characteristics including socioeconomic status, education, blood transfusion, transplantation, sexual promiscuity and number of previous pregnancies or deliveries did not show an association with CMV exposure.

Conclusions

This is the first seroepidemiology study of CMV infection in pregnant women in Mexico. A number of known factors associated with CMV infection were not associated with CMV exposure in the women studied. Further studies to determine routes of CMV infection in pregnant women in Mexico are needed.

【 授权许可】

   
2014 Alvarado-Esquivel et al.; licensee BioMed Central Ltd.

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