Transcultural adaptation and initial validation of Brazilian-Portuguese version of the Basel assessment of adherence to immunosuppressive medications scale (BAASIS) in kidney transplants

BMC Nephrology

Helady Sanders-Pinheiro³  Sabina De Geest²  Natalia Maria da Silva Fernandes³  Fabiane Rossi dos Santos Grincenkov³  Fernando Colugnati³  Neimar da Silva Fernandes¹  Elisa de Oliveira Marsicano³ 

[1] Centre for Public Policy and Education Evaluation (CAED), Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil;Institute of Nursing Science, University of Basel, Basel, Switzerland;Núcleo Interdisciplinar de Estudos e Pesquisas em Nefrologia [NIEPEN], Juiz de Fora, Minas Gerais, Brazil

关键词: Validation;    Transplantation;    Medication nonadherence;    Immunosuppression;    Patient adherence;   

Others  :  1082931
DOI  :  10.1186/1471-2369-14-108

 received in 2012-10-18, accepted in 2013-05-15,  发布年份 2013

【 摘 要 】

Background

Transplant recipients are expected to adhere to a lifelong immunosuppressant therapeutic regimen. However, nonadherence to treatment is an underestimated problem for which no properly validated measurement tool is available for Portuguese-speaking patients. We aimed to initially validate the Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS^®) to accurately estimate immunosuppressant nonadherence in Brazilian transplant patients.

Methods

The BAASIS^® (English version) was transculturally adapted and its psychometric properties were assessed. The transcultural adaptation was performed using the Guillemin protocol. Psychometric testing included reliability (intraobserver and interobserver reproducibility, agreement, Kappa coefficient, and the Cronbach’s alpha) and validity (content, criterion, and construct validities).

Results

The final version of the transculturally adapted BAASIS^® was pretested, and no difficulties in understanding its content were found. The intraobserver and interobserver reproducibility variances (0.007 and 0.003, respectively), the Cronbach’s alpha (0.7), Kappa coefficient (0.88) and the agreement (95.2%) suggest accuracy, preciseness and reliability. For construct validity, exploratory factorial analysis demonstrated unidimensionality of the first three questions (r = 0.76, r = 0.80, and r = 0.68). For criterion validity, the adapted BAASIS^® was correlated with another self-report instrument, the Measure of Adherence to Treatment, and showed good congruence (r = 0.65).

Conclusions

The BAASIS^® has adequate psychometric properties and may be employed in advance to measure adherence to posttransplant immunosuppressant treatments. This instrument will be the first one validated to use in this specific transplant population and in the Portuguese language.

【 授权许可】

   
2013 Marsicano et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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