Prevalence and factors associated with low bone mineral density in Saudi women: a community based survey

BMC Musculoskeletal Disorders

Riad Sulaimani⁴  Mona Fouda⁴  Fawzia Habib⁵  Saleh Othman¹  Abdullah Al-Sharif²  Shaffi Ahamed Shaikh⁶  Salwa Tayel⁶  Ambreen Kazi³  AlJohara M AlQuaiz⁶ 

[1] Department of Nuclear Medicine, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia;Council of Co-operative Health Insurance, Ministry of Health, Riyadh, Kingdom of Saudi Arabia;Princess Nora Bent Abdallah Women Health Research Chair, College of Medicine, King Saud University, PO Box 231831, Riyadh 11321, Kingdom of Saudi Arabia;Department of Medicine-Endocrinology, College of Medicine, King Saud University, Riyadh 12371, Saudi Arabia;Departement of Obstetrics & Gynecology, College of Medicine, Taibah University, Al Medina, Al Munawara, Kingdom of Saudi Arabia;Department of Family & Community Medicine, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia

关键词: Dietary factors;    Women;    Low bone mineral density;   

Others  :  1128954
DOI  :  10.1186/1471-2474-15-5

 received in 2013-05-04, accepted in 2014-01-02,  发布年份 2014

【 摘 要 】

Background

Low bone mineral density (BMD) is a public health issue in Saudi Arabia. This study measured the prevalence and factors associated with low BMD in Saudi women in Riyadh, Saudi Arabia.

Methods

A cross sectional study using two stage cluster sampling technique was conducted in Riyadh, 2009. Thirty clusters, each comprising of 300 houses were randomly chosen and from each cluster 38–40 households were selected to identify 1150 women of >40 years. Women were invited to primary health care center for filling of self-administered questionnaire (n = 1069) comprising of sociodemographic, health, diet and physical activity variables. 1008 women underwent screening for low BMD using the quantitative ultrasound technique. 535 (53%) women with positive screening test were referred to King Khalid Hospital for Dual X-ray Energy absorptiometry (DXA).

Results

362 women underwent DXA and 212 (39.6%) were screened low BMD either at lumbar spine or femur neck. Mean age of women was 55.26(±8.84) years. Multivariate logistic analysis found; being aged 61 to 70 years (OR 2.75, 95% CI: 1.32-1.48), no literacy (OR 2.97, 95% CI:1.44 - 6.12) or primary education (OR 4.12, 95% CI:2.05-8.29), history of fractures (OR 2.20, 95% CI:1.03- 4.69) and not drinking laban(diluted yogurt) (OR 2.81, 95% CI:1.47- 5.37) significantly associated with low BMD.

Conclusions

Women with low level of education, who do not drink laban and had history of fractures were at high risk of low BMD.

【 授权许可】

   
2014 Al Quaiz et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

• [1]NIH: Consensus development panel on osteoporosis, prevention, diagnosis and therapy. JAMA 2001, 285:785-795.
• [2]Cooper C, Campion G, Melton LJ 3rd: Hip fractures in the elderly: a world-wide projection. Osteoporos Int 1999, 22:285-289.
• [3]Ghannam NN, Hammami MM, Bakheet SM, Khan BA: Bone mineral density of the spine and femur in healthy Saudi females: relation to vitamin D status, pregnancy and lactation. Calcif Tissue Int 1999, 65:23-28.
• [4]El-Desouki MI: Osteoporosis in postmenopausal Saudi women using dual X-Ray bone densitometry. Saudi Med J 2003, 24:953-956.
• [5]Sadat-Ali M, Al-Habdan IM, Al–Mulhim FA, El-Hassan AY: Bone mineral density among postmenopausal Saudi women. Saudi Med J 2004, 25:1623-1625.
• [6]Ardawi MS, Maimany AA, Bahksh TM, Nasrat HA, Millaat WA, Al-Raddadi RM: Bone mineral density of the spine and femur in healthy Saudi Arabs. Osteoporos Int 2005, 16:43-55.
• [7]Maalouf G, Gannagé-Yared MH, Ezzedine J, et al.: Lebanese osteoporosis prevention society, Shariati hospital, Iran. Middle East and North Africa consensus on osteoporosis. J Musculoskelet Neuronal Interact 2007, 7:131-143.
• [8]National Osteoporosis Foundation: Clinician’s Guide to prevention and treatment of osteoporosis. Washington, DC: National Osteoporosis Foundation; 2010. Accessed from : http://www.nof.org/files/nof/public/content/file/344/upload/159.pdf webcite
• [9]Rouzi AA, Al Sibiani SA, Al Senani NS, Radaddi RM, Aradawi MS: Independent predictors of all osteoporosis related fractures among healthy Saudi postmenopausal women :the CEOR study. Bone 2012, 50:713-722.
• [10]Cummings SR, Bales D, Black DM: Clinical use of bone densitometry. Scientific review. JAMA 2002, 288:1889-1897.
• [11]Moayyeri A, Adams JE, Adler RA, et al.: Quantitative ultrasound of the heel and fracture risk assessment: an updated meta-analysis. Osteoporos Int 2012, 23:143-153.
• [12]World Health Organization: Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Series 1994, 843:1-129.
• [13]Sadat-Ali M, Al-Habdan IM, Al-Turki HA, Azam MQ: An epidemiological analysis of the incidence of osteoporosis and osteoporosis-related fractures among the Saudi Arabian population. Ann Saudi Med 2012, 32:637-641.
• [14]Looker CA, Borrud GL, Dawson-Hughes B, Shepherd AJ, Wright CN: Osteoporosis or Low bone mineral at the femur neck or lumbar spine in older adults: United States, 2005–2008. 2012. NCHS Data Brief. No. 93. Accessed from http://www.cdc.gov/nchs/data/databriefs/db93.pdf webcite
• [15]Raef H, Al-Bugami M, Balharith S, et al.: Recommendations for the diagnosis and management of osteoporosis: a local perspective. Ann Saudi Med 2011, 3:111-128.
• [16]Mantila RSM, Hurd AL, Xu H, Fuchs RK, Warden SJ: Age related changes in proximal humerus bone health in healthy, white males. Osteoporos Int 2012, 23:2775-2783.
• [17]Luong ML, Cleveland RJ, Nyrop KA, Callahan LF: Social determinants and osteoarthritis outcomes. Aging health 2012, 8:413-437.
• [18]Svejme O, Ahlborg HG, Nilsson JÅ, Karlsson MK: Low BMD is an independent predictor of fracture and early menopause of mortality in post-menopausal women–a 34-year prospective study. Maturitas 2013, 74:341-345.
• [19]Barcenilla-Wong AL, Chen JS, March LM: Concern and risk perception of osteoporosis and fracture among post-menopausal Australian women: results from the global longitudinal study of osteoporosis in women (GLOW) cohort. Arch Osteoporos 2013, 8:155.
• [20]Browner WS, Pressman AR, Nevitt MC, Cummings SR: Mortality following fractures in older women. The study of osteoporotic fractures. Arch Inter Med 1996, 156:1521-1525.
• [21]Dalal BD, Sadat-Ali M: Economic implications of osteoporosis-related femoral fractures in Saudi Arabian society. Calcif Tissue Int 2007, 81:455-458.
• [22]Hui YH, Evranuz EÖ: Handbook of animal-based fermented food and beverage technology. Second edition. CRC Press; 2012:814.
• [23]Hitchins DA, McDonough EF: Prophylactic and therapeutic aspects of fermented milk. Am J Nutr 1989, 49:675-684.
• [24]Seneca H, Gaymont S: Clinical uses of yogurt. J Am Geriatr Soc l957, 5:932-935.
• [25]Savaiano DA, Levitt MD: Nutritional and therapeutic aspects of fermented dairy products. J Dent Child l984, 1:305-308.
• [26]Kimoto-Nira H, Suzuki C, Kobayashi M, Sasaki K, Kurisaki J, Mizumachi K: Anti-ageing effect of a lactococcal strain: analysis using senescence-accelerated mice. Br J Nutr 2007, 98:1178-1186.
• [27]Cheong SH, Chang KJ: The preventive effect of fermented milk supplement containing tomato (lycopersionesculentum) and taurine on bone loss in ovariectomizedrats. Adv Exp Med Biol 2009, 643:333-340.
• [28]Calcium and vitamin D important at every age http://www.niams.nih.gov/health_info/bone/bone_health/nutrition/ webcite
• [29]Office of dietary supplements. National institute of health Accessed at: http://ods.od.nih.gov/ webcite
• [30]Shen CL, Yeh JK, Cao JJ, Wang JS: Green tea and bone metabolism. Nutr Res 2009, 29:437-456.
• [31]Al-Habdan IM, Sadat-Ali M, Al-Muhanna FA, Al-Elq AH, Al-Mulhim AA: Bone mass measurement using quantitative ultrasound in healthy Saudi women. A cross-sectional screening. Saudi Med J 2009, 30:1426-1431.
• [32]Sadat–Ali M, Al-Elq A, Al-Habdan I, et al.: Quantitative ultrasound (QUS) of the oscalcis in Saudi women: defining Saudi reference value for the diagnosis of low bone mass. Arch Osteoporos 2010, 5:139-144.
• [33]Ardawi MS, Qari MH, Rouzi AA, Maimani AA, Raddadi RM: Vitamin D status in relation to obesity, bone mineral density, bone turnover markers and vitamin D receptor genotypes in healthy Saudi pre- and postmenopausal women. Osteoporos Int 2011, 22:463-475.