期刊论文详细信息
BMC Pulmonary Medicine
Unilateral phrenic nerve lesion in Lyme neuroborreliosis
Roland Nau2  Paul Lingor3  Jörg Larsen1  Marija Djukic2 
[1] Department of Clinical Radiology, Weende Teaching Hospitals, An der Lutter 24, 37075, Goettingen, Germany;Department of Geriatrics, Weende Teaching Hospitals, An der Lutter 24, 37075, Goettingen, Germany;Department of Neurology, University Medical Centre Goettingen, Robert-Koch-Str. 40, 37075, Goettingen, Germany
关键词: Ceftriaxone;    Doxycycline;    Diaphragm;    Dyspnoea;    Lyme neuroborreliosis;    Unilateral;    Phrenic nerve palsy;   
Others  :  1131301
DOI  :  10.1186/1471-2466-13-4
 received in 2012-06-27, accepted in 2013-01-10,  发布年份 2013
PDF
【 摘 要 】

Background

Among a variety of more common differential diagnoses, the aetiology of acute respiratory failure includes Lyme neuroborreliosis.

Case presentation

We report an 87-years old huntsman with unilateral phrenic nerve palsy as a consequence of Lyme neuroborreliosis.

Conclusion

Although Lyme neuroborreliosis is a rare cause of diaphragmatic weakness, it should be considered in the differential workup because of its potentially treatable nature.

【 授权许可】

   
2013 Djukic et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150301035738862.pdf 678KB PDF download
Figure 1. 36KB Image download
【 图 表 】

Figure 1.

【 参考文献 】
  • [1]Hansen K, Lebech AM: The clinical and epidemiological profile of Lyme neuroborreliosis in Denmark 1985–1990. A prospective study of 187 patients with Borrelia burgdorferi specific intrathecal antibody production. Brain 1992, 115:399-423.
  • [2]Ljostad U, Skarpaas T, Mygland A: Clinical usefulness of intrathecal antibody testing in acute Lyme neuroborreliosis. Eur J Neurol 2007, 14:873-876.
  • [3]Bannwarth A: Chronische lymphozytäre Meningitis, entzündliche Polyneuritis and Rheumatismus. Arch Psychiatr Nervenkr 1941, 113:284-376.
  • [4]Djukic M, Schmidt-Samoa C, Spreer A, Lange P, Neubieser K, Eiffert H, Nau R, Schmidt H: Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis. J Neurol 2012, 259:630-636.
  • [5]Lebech AM, Hansen K, Brandrup F, Clemmensen O, Halkier-Sørensen L: Diagnostic value of PCR for detection of Borrelia burgdorferi DNA in clinical specimens from patients with erythema migrans and Lyme neuroborreliosis. Mol Diagn 2000, 5:139-150.
  • [6]Steere AC: Lyme disease. NEJM 1989, 321:586-596.
  • [7]Abbott RA, Hammans S, Margarson M, Aji BM: Diaphragmatic paralysis and respiratory failure as a complication of Lyme disease. J Neurol Neurosurg Psychiatry 2005, 76:1306-1307.
  • [8]Kumar N, Folger WN, Bolton CF: Dyspnea as the predominant manifestation of bilateral phrenic neuropathy. Mayo Clin Proc 2004, 79:1563-1565.
  • [9]Sigler S, Kershaw P, Scheuch R, Sklarek H, Halperin J: Respiratory failure due to Lyme meningoradiculitis. Am J Med 1997, 103:544-547.
  • [10]Faul JL, Ruoss S, Doyle RL, Kao PN: Diaphragmatic paralysis due to Lyme disease. Eur Respir J 1999, 13:700-702.
  • [11]Winterholler M, Erbguth FJ: Tick bite induced respiratory failure. Diaphragm palsy in Lyme disease. Intensive Care Med 2001, 27:1095.
  • [12]Ishaq S, Quinet R, Saba J: Phrenic nerve paralysis secondary to Lyme neuroborreliosis. Neurology 2002, 59:1810-1811.
  • [13]van Egmond ME, Luijckx GJ, Kramer H, Benne CA, Slebos DJ, van Assen S: Diaphragmatic weakness caused by neuroborreliosis. Clin Neurol Neurosurg 2011, 113:153-155.
  • [14]Tauber SC, Ribes S, Ebert S, Heinz T, Fingerle V, Bunkowski S, Kugelstadt D, Spreer A, Jahn O, Eiffert H, Nau R: Long-term intrathecal infusion of outer surface protein C from Borrelia burgdorferi causes axonal damage. J Neuropathol Exp Neurol 2011, 70:748-757.
  • [15]Lünemann JD, Gelderblom H, Sospedra M, Quandt JA, Pinilla C, Marques A, Martin R: Cerebrospinal fluid-infiltrating CD4+ T cells recognize Borrelia burgdorferi lysine-enriched protein domains and central nervous system autoantigens in early lyme encephalitis. Infect Immun 2007, 75:243-251.
  • [16]Kaiser R, Kern A, Kampa D, Neumann-Haefelin D: Prevalence of antibodies to Borrelia burgdorferi and tick-borne encephalitis virus in an endemic region in southern Germany. Zentralbl Bakteriol 1997, 286:534-541.
  • [17]Hammers-Berggren S, Hansen K, Lebech AM, Karlsson M: Borrelia burgdorferi-specific intrathecal antibody production in neuroborreliosis: a follow-up study. Neurology 1993, 43:169-175.
  • [18]Schmidt C, Plate A, Angele B, Pfister HW, Wick M, Koedel U, Rupprecht TA: A prospective study on the role of CXCL13 in Lyme neuroborreliosis. Neurology 2011, 76:1051-1058.
  • [19]Rupprecht TA, Pfister HW, Angele B, Kastenhauer S, Wilske B, Koedel U: The chemokine CXCL 13 (BLC): a putative diagnostic marker for neuroborreliosis. Neurology 2005, 65:448-450.
  • [20]Kowarik MC, Cepok S, Sellner J, Grummel V, Weber MS, Korn T, Berthele A, Hemmer B: CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation. J Neuroinflammation 2012, 9:93. BioMed Central Full Text
  • [21]Halperin JJ: Neurologic manifestations of lyme disease. Curr Infect Dis Rep 2011, 13:360-366.
  • [22]Mygland A, Skarpaas T, Ljøstad U: Chronic polyneuropathy and Lyme disease. Eur J Neurol 2006, 13:1213-1215.
  • [23]Ackermann R, Rehse-Kupper B, Gollmer E, Schmidt R: Chronic neurologic manifestations of erythema migrans borreliosis. Ann N Y Acad Sci 1988, 539:16-23.
  • [24]Kaiser R: Clinical courses of acute and chronic neuroborreliosis following treatment with ceftriaxone. Nervenarzt 2004, 75:553-557.
  文献评价指标  
  下载次数:11次 浏览次数:22次