Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions: a pilot feasibility trial

BMC Gastroenterology

Ichiro Hirata¹  Tomiyasu Arisawa²  Masami Iwata¹  Mitsuo Nagasaka¹  Yoshihito Nakagawa¹  Hiroshi Fujita¹  Toshiaki Kamano¹  Naoko Maruyama¹  Takamitsu Ishizuka¹  Daisuke Yoshioka¹  Masaaki Okubo¹  Joh Yonemura¹  Masakatsu Nakamura²  Tomoyuki Shibata¹  Tomomitsu Tahara¹  Yoshio Kamiya¹  Takafumi Omori¹ 

[1] Department of Gastroenterology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan;Department of Gastroenterology, Kanazawa Medical University, 1-1 Daigaku, Uchinadamachi, Ishikawa 920-0293, Japan

关键词: Gastric cancer;    Polypoid lesions;    Magnifying endoscopy;    Stomach;    NBI;   

Others  :  1113139
DOI  :  10.1186/1471-230X-12-17

 received in 2011-06-26, accepted in 2012-02-22,  发布年份 2012

【 摘 要 】

Background

Several study showed usefulness of microscopic capillaries, seen by magnifying narrow band imaging (NBI) endoscopy for predicting histopathology among superficial depressed or flat elevated gastric neoplasia (GN). Here we assessed the diagnostic efficacy of magnifying NBI for predicting histopathology among gastric protruding/or polypoid lesions.

Methods

Using endoscopic pictures of magnifying NBI from 95 protruding/or polypoid lesions (19 fundic gland polyps: FGP, 47 hyperplastic polyps: HP, and 29 GN), fine mucosal patterns were classified into four categories: small round, prolonged, villous or ridge, and unclear patterns, and micro vascular patterns were classified into five categories: honey comb, dense vascular, fine net work, core vascular, and unclear patterns.

Results

Most suggestive micro vascular patterns for predicting FGP, and HP were honeycomb (sensitivity 94.7%, specificity 97.4%), and dense vascular patterns (sensitivity 93.6%, specificity 91.6%), respectively. Fine net work, core vascular, and unclear patterns presented higher specificity (97%, 100%, and 100%) for predicting GN, and diagnostic efficacy of combined of those patterns was favorable (sensitivity 86.2%, specificity 97.0%).

Conclusion

Micro vascular patterns by using magnifying NBI provides meaningful information for predicting the histopathology of gastric protruding/or polypoid lesions.

【 授权许可】

   
2012 Omori et al; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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