Prevalence of tuberculous lymphadenitis in Gondar University Hospital, NorthwestEthiopia

BMC Public Health

Andebet Ambachew¹  Eden Woldegerima¹  Belete Biadgo¹  Dagnachew Muluye¹ 

[1] School of Biomedical and Laboratory Sciences, College of Medicine and HealthSciences, University of Gondar, P.O. Box. 196, Gondar, Ethiopia

关键词: Ethiopia;    Fine needle aspiration cytology;    Tuberculous lymphadenitis;   

Others  :  1162246
DOI  :  10.1186/1471-2458-13-435

 received in 2012-09-19, accepted in 2013-04-30,  发布年份 2013

【 摘 要 】

Background

Tuberculous is the leading cause of death worldwide with a large number of deaths occurring in developing countries. Tuberculous lymphadenitis is among the most common presentations of extra pulmonary tuberculous. This study attempts to determine the magnitude of tuberculous lymphadenitis from patients with lymph node aspirate in Gondar University Hospital, Northwest Ethiopia.

Methods

Retrospective study was conducted. Data were collected from registration book of Gondar university Hospital pathology laboratory after checking the completeness of patient’s necessary information like age, sex and fine needle aspiration cytology results. Data were entered and analyzed using SPSS version 16 statistical package. Chi-square test was done to determine associations.

Result

A total of 3,440 lymph node aspirates were examined using fine needle aspiration cytology. Of these, 2,392 (69.5%) cases were found to have tuberculous lymphadenitis. Male 1647(47.9%) to female 1793(52.1%) ratio of all study subjects were 0.9:1. Females (54.1%) were more affected than males (45.9%). Age, sex and site of aspiration were found to be statistically associated with tuberculous lymphadenitis (p-value < 0.001). The age group of 15–24 years had the highest prevalence of tuberculous lymphadenitis followed by those of 25–34 years old. The most affected sites were cervical lymph nodes (47.5%) followed by auxiliary (19.4%) and submandibular (12.9%) lymph node regions. None of the records documented the HIV status of subjects.

Conclusion

The prevalence of tuberculous from lymph node aspirate was found to be higher involving the frequently affected site of cervical lymph node. The HIV status of patients with all forms of tuberculous should have to be checked and documented. Further prospective and advanced studies are recommended to determine the specific etiologic agents and contributing factors.

【 授权许可】

   
2013 Muluye et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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