Hand, hip and knee osteoarthritis in a Norwegian population-based study - The MUST protocol

BMC Musculoskeletal Disorders

Bård Natvig¹  Hanne Edvardsen⁶  Sølve Sesseng⁶  Margreth Grotle⁵  Gunnar Flugsrud³  Ingvild Kjeken⁵  Barbara Slatkowsky-Christensen²  Till Uhlig²  Kåre Birger Hagen⁵  Silvia Rollefstad²  Anne Grete Semb²  Britt Elin Øiestad⁴  Sella Provan²  Hilde Berner Hammer²  Ida K Haugen²  Unni-Berit Schjervheim⁷  Dag Bruusgaard¹  Lars Nordsletten³  Lars Engebretsen³  Tore K Kvien²  May Arna Risberg⁴  Nina Østerås⁵ 

[1] Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway;Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway;Department of Orthopaedic Surgery, Oslo University Hospital Ullevål, Oslo, Norway;Norwegian Research Center for Active Rehabilitation Department of Orthopaedic Surgery, Oslo University Hospital, Oslo, Norway;National Resource, Center for rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway;Department of Radiology, Diakonhjemmet Hospital, Oslo, Norway;Primary Health Care, Ullensaker Municipality, Akershus, Norway

关键词: Study protocol;    Observational study;    Knee;    Hip;    Hand;    Osteoarthritis;   

Others  :  1130374
DOI  :  10.1186/1471-2474-14-201

 received in 2013-05-02, accepted in 2013-06-21,  发布年份 2013

【 摘 要 】

Background

Knowledge about the prevalence and consequences of osteoarthritis (OA) in the Norwegian population is limited. This study has been designed to gain a greater understanding of musculoskeletal pain in the general population with a focus on clinically and radiologically confirmed OA, as well as risk factors, consequences, and management of OA.

Methods/Design

The Musculoskeletal pain in Ullensaker STudy (MUST) has been designed as an observational study comprising a population-based postal survey and a comprehensive clinical examination of a sub-sample with self-reported OA (MUST OA cohort). All inhabitants in Ullensaker municipality, Norway, aged 40 to 79 years receive the initial population-based postal survey questionnaire with questions about life style, general health, musculoskeletal pain, self-reported OA, comorbidities, health care utilisation, medication use, and functional ability. Participants who self-report OA in their hip, knee and/or hand joints are asked to attend a comprehensive clinical examination at Diakonhjemmet Hospital, Oslo, including a comprehensive medical examination, performance-based functional tests, different imaging modalities, cardiovascular assessment, blood and urine samples, and a number of patient-reported questionnaires including five OA disease specific instruments. Data will be merged with six national data registries. A subsample of those who receive the questionnaire has previously participated in postal surveys conducted in 1990, 1994, and 2004 with data on musculoskeletal pain and functional ability in addition to demographic characteristics and a number of health related factors. This subsample constitutes a population based cohort with 20 years follow-up.

Discussion

This protocol describes the design of an observational population-based study that will involve the collection of data from a postal survey on musculoskeletal pain, and a comprehensive clinical examination on those with self-reported hand, hip and/or knee OA. These data, in addition to data from national registries, will provide unique insights into clinically and radiologically confirmed OA with respect to risk factors, consequences, and management.

【 授权许可】

   
2013 Østerås et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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