期刊论文详细信息
BMC Research Notes
Evaluation of objective and subjective indicators of death in a period of one year in a sample of prevalent patients under regular hemodialysis
Paulo R Santos1 
[1] Sobral School of Medicine, Federal University of Ceará, Avenida Comandante Maurocélio Rocha Pontes, 100 CEP 62.042-280, Sobral, Ceará, Brazil
关键词: Coping;    Depression;    Quality of life;    Mortality;    Hemodialysis;    End-stage renal disease;   
Others  :  1166788
DOI  :  10.1186/1756-0500-5-24
 received in 2011-10-31, accepted in 2012-01-11,  发布年份 2012
PDF
【 摘 要 】

Background

To identify objective and subjective indicators of death in prevalent hemodialysis (HD) patients in a follow-up study of 12 months.

Methods

The study included end-stage renal disease patients undergoing HD and analyzed demographic and laboratory data from the dialysis unit's records. Baseline data concerning socioeconomic status, comorbidity, quality of life level, coping style and depression were also assessed. For variables that differed in the comparison between survivors and non-survivors, Cox proportional hazards for death were calculated.

Results

The mortality rate was 13.0%. Non-survivors differed in age, comorbidity, inclusion on the transplant waiting list and physical functioning score. The hazard ratios of death were 8.958 (2.843-28.223; p < 0.001) for comorbidity, 3.992 (1.462-10.902; p = 0.007) for not being on the transplant waiting list, 1.038 (1.012-1.066; p = 0.005) for age, and 0.980 (0.964-0.996; p = 0.014) for physical functioning.

Conclusions

Comorbidity, not being on the transplant waiting list, age and physical functioning, which reflects physical status, must be seen as risk indicators of death among patients undergoing HD.

【 授权许可】

   
2011 Santos; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150416054446922.pdf 225KB PDF download
【 参考文献 】
  • [1]Quinton W, Dillard D, Scribner BH: Cannulation of blood vessels for prolonged hemodialysis. Trans Am Soc Artif Intern Organs 1960, 6:104-113.
  • [2]Brazilian Society of Nephrology: Censo. [http://www.sbn.org.br/censos/censos_anteriores/censo_2008.pdf] webcite
  • [3]Himmelfarb J: Uremic toxicity, oxidative stress, and hemodialysis as renal replacement therapy. Semin Dial 2009, 22:636-643.
  • [4]Goodkin DA, Young EW, Kurokawa K, Prutz KG, Levin NW: Mortality among hemodialysis patients in Europe, Japan, and the United States: case-mix effects. Am J Kidney Dis 2004, 44:16-21.
  • [5]Sesso R: Epidemiologia da doença renal crônica no Brasil e sua prevenção. [http://www.cve.saude.sp.gov.br/htm/cronicas/irc_prof.htm] webcite
  • [6]Santos PR: Qualidade de vida relacionada à saúde entre pacientes de baixa renda em hemodiálise. In Atualidades em nefrologia. Volume 11. Edited by Cruz J. São Paulo: Sarvier; 2010::428-434.
  • [7]Santos PR: Associação de qualidade de vida com hospitalização e óbito em pacientes portadores de doença renal crônica em hemodiálise. J Bras Nefrol 2005, 27:184-190.
  • [8]Cicconelli RM, Ferraz MB, Santos W, Meinão I, Quaresma MR: Brazilian-Portuguese version of the SF-36: a reliable and valid quality of life outcome measure. Rev Bras Reumatol 1999, 39:143-150.
  • [9]Jalowiec A, Powers MJ: Stress and coping in hypertensive and emergency room patients. Nurs Res 1981, 30:10-15.
  • [10]Souza-Talarico JN, Chaves EC, Nitrini R, Caramelli P: Stress and coping in older people with Alzheimer's disease. J Clin Nurs 2009, 18:457-465.
  • [11]Lazarus RS, Folkman S: Stress, appraisal, and coping. New York: Springer Publishing; 1984.
  • [12]Andresen EM, Malmgren JA, Carter WB, Patrick DL: Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale). Am J Prev Med 1994, 10:77-84.
  • [13]Brazilian Association of Research Institutes: Critério Brasil. [http://www.marketanalysis.com.br/arquivos_download/biblioteca/cceb-1.pdf] webcite
  • [14]Khan IH, Campbell MK, Cantarovich D, Catto GRD, Edward N, Fontenaille C, Fleming LW, Gerlag PGG, Van Hamersvelt HW, Henderson IS, Koene RAP, Papadimitriou M, Ritz E, Russel IT, Stier E, Tsakiris D, MacLeod AM: Survival on renal replacement therapy in Europe: Is there a "centre effect". Nephrol Dial Tranplant 1996, 11:300-307.
  • [15]Daugirdas JT: Second generation logarithmic estimates of single-pool variable volume Kt-V: an analysis of error. J Am Soc Nephrol 1993, 4:205-213.
  • [16]Revuelta KL, López FJG, Moreno FA, Alonso J: Perceived mental health at the start of dialysis as a predictor of morbidity and mortality in patients with end-stage renal disease. Nephrol Dial Transplant 2004, 19:2347-2353.
  • [17]Lopes AA, Bragg J, Young E, Goodkin D, Mapes D: Depression as a predictor of mortality and hospitalization among hemodialysis patients in the United States and Europe. Kidney Int 2002, 62:199-207.
  • [18]Lowrie EG, Curtin RB, Lepain N, Schatell D: Medical Outcomes Study Short Form-36: a consistent and powerful predictor of morbidity and mortality in dialysis patients. Am J Kidney Dis 2003, 41:1286-1292.
  • [19]Rai M, Rustaqi T, Rustaqi S, Kohli R: Depression, insomnia and sleep apnea in patients on maintenance hemodialysis. Indian J Nephrol 2011, 21:223-229.
  • [20]Van Manen JG, Korevaar JC, Dekker FW, Boeschoten EW, Bossuyt PMM, Krediet RT: Adjustment for comorbidity in studies on health status in ESRD patiens: Which comorbidity index to use. J Am Soc Nephrol 2003, 14:478-485.
  • [21]Craven J, Littlefield C, Rodin G, Murray M: The end-stage renal disease severity index (ESRD-SI). Psychol Med 1991, 21:237-243.
  • [22]Schag CC, Heinrich RL, Ganz PA: Karnofsky performance status revisited: Reliability, validity, and guidelines. J Clin Oncology 1984, 2:187-193.
  文献评价指标  
  下载次数:17次 浏览次数:106次