Asymptomatic tracheal MALT lymphoma discovered on spirometric findings presenting with elevated respiratory resistance

BMC Research Notes

Fumitaka Ogushi⁴  Tadashi Yoshino¹  Hiroko Toda¹  Fumie Suehiro³  Hirofumi Nakanishi³  Hisanori Machida⁴  Tsutomu Shinohara²  Naoki Kadota⁴ 

[1] Department of Pathology, Okayama University, 2-5-1 Shikata-cho, Okayama 700-8525, Japan;Department of Clinical Investigation, National Hospital Organization National Kochi Hospital, 1-2-25 Asakuranishimachi, Kochi 780-8077, Japan;Kochi Kenshin Clinic, 2-4-36 Chiyori-cho, Kochi 780-0806, Japan;Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, 1-2-25 Asakuranishimachi, Kochi 780-8077, Japan

关键词: Impulse oscillometry;    Flow–volume curve;    Central airway obstruction;   

Others  :  1232411
DOI  :  10.1186/s13104-015-1218-5

 received in 2014-08-09, accepted in 2015-05-29,  发布年份 2015

【 摘 要 】

Background

Central airway obstruction (CAO) may be caused by various etiologies. However, conventional chest X-rays are rarely diagnostic for patients with CAO.

Case presentation

We here described a 64-year-old asymptomatic female with tracheal mucosa-associated lymphoid tissue lymphoma discovered on spirometric findings during a complete physical examination. The plateau of forced expiratory flow was consistent with CAO. A decreased peak expiratory flow rate was noted at least 3 years before the diagnosis, and was attributed to an insufficient effort by the patient. Impulse oscillometric measurements, which were taken during quiet breathing and were effort-independent, suggested elevated respiratory resistance. These abnormalities completely disappeared after radiation therapy.

Conclusion

The addition of impulse oscillometry to spirometry may be useful for screening CAO in routine health examinations.

【 授权许可】

   
2015 Kadota et al.

【 图 表 】

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【 参考文献 】

• [1]Mathisen DJ: Primary tracheal tumor management. Surg Oncol Clin N Am 1999, 8:307-326.
• [2]Fidias P, Wright C, Harris NL, Urba W, Grossbard ML: Primary tracheal non-Hodgkin’s lymphoma. A case report and review of the literature. Cancer 1996, 77:2332-2338.
• [3]Zinzani PL, Magagnoli M, Galieni P, Martelli M, Poletti V, Zaja F, et al.: Nongastrointestinal low-grade mucosa-associated lymphoid tissue lymphoma: analysis of 75 patients. J Clin Oncol 1999, 17:1254-1258.
• [4]Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, et al.: Interpretative strategies for lung function tests. Eur Respir J 2005, 26:948-968.
• [5]Yamauchi Y, Kohyama T, Jo T, Nagase T: Dynamic change in respiratory resistance during inspiratory and expiratory phases of tidal breathing in patients with chronic obstructive pulmonary disease. Int J Chron Obstr Pulm Dis 2012, 7:259-269.
• [6]Shirai T, Mori K, Mikamo M, Shishido Y, Akita T, Morita S, et al.: Usefulness of colored 3D imaging of respiratory impedance in asthma. Allergy Asthma Immunol Res 2013, 5:322-328.
• [7]Thieblemont C, Bastion Y, Berger F, Rieux C, Salles G, Dumontet C, et al.: Mucosa-associated lymphoid tissue gastrointestinal and nongastrointestinal lymphoma behavior: analysis of 108 patients. J Clin Oncol 1997, 15:1624-1630.
• [8]Okubo K, Miyamoto N, Komaki C: Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the trachea: a case of surgical resection and long term survival. Thorax 2005, 60:82-83.
• [9]Ding J, Chen Z, Shi M: Tracheal stenting for primary tracheal mucosa-associated lymphoid tissue lymphoma. Eur J Med Res 2013, 18:8. BioMed Central Full Text
• [10]Tsurutani J, Kinoshita A, Kaida H, Fujii H, Narasaki F, Fukuda M, et al.: Bronchoscopic therapy for mucosa-associated lymphoid tissue lymphoma of the trachea. Intern Med 1999, 38:276-278.
• [11]Tsang RW, Gospodarowicz MK, Pintilie M, Wells W, Hodgson DC, Sun A, et al.: Localized mucosa-associated lymphoid tissue lymphoma treated with radiation therapy has excellent clinical outcome. J Clin Oncol 2003, 21:4157-4164.
• [12]Hollingsworth HM: Wheezing and stridor. Clin Chest Med 1987, 8:231-240.
• [13]Geffin B, Grillo HC, Cooper JD, Pontoppidan H: Stenosis following tracheostomy for respiratory care. JAMA 1971, 216:1984-1988.
• [14]Miller RD, Hyatt RE: Evaluation of obstructing lesions of the trachea and larynx by flow–volume loops. Am Rev Respir Dis 1973, 108:475-481.
• [15]Stoller JK: Spirometry: a key diagnostic test in pulmonary medicine. Clevel Clin J Med 1992, 59:75-78.
• [16]Horan T, Mateus S, Beraldo P, Araújo L, Urschel J, Urmenyi E, et al.: Forced oscillation technique to evaluate tracheostenosis in patients with neurologic injury. Chest 2001, 120:69-73.
• [17]Verbanck S, de Keukeleire T, Schuermans D, Meysman M, Vincken W, Thompson B: Detecting upper airway obstruction in patients with tracheal stenosis. J Appl Physiol 2010, 109:47-52.
• [18]Handa H, Huang J, Murgu SD, Mineshita M, Kurimoto N, Colt HG, et al.: Assessment of central airway obstruction using impulse oscillometry before and after interventional bronchoscopy. Respir Care 2014, 59:231-240.
• [19]Oostveen E, MacLeod D, Lorino H, Farré R, Hantos Z, Desager K, et al.: ERS task force on respiratory impedance measurements: the forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur Respir J 2003, 22:1026-1041.
• [20]LaPrad AS, Lutchen KR: Respiratory impedance measurements for assessment of lung mechanics: focus on asthma. Respir Physiol Neurobiol 2008, 163:64-73.