Orbital rhabdomyosarcoma with skin metastasis: a case report

BMC Research Notes

Hassan Errihani²  Basma Elkhannoussi¹  Hind Mrabti²  Saber Boutayeb²  Narjiss Berrada²  Imane Ouziane²  Salima Touri¹  Fadwa Elomrani² 

[1] Department of Pathology, National Institute of Oncology, Rabat, Morocco;Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco

关键词: Radiotherapy;    Chemotherapy;    Treatment;    Immunohistochemistry;    Cutaneous metastasis;    Rhabdomyosarcoma;   

Others  :  1129280
DOI  :  10.1186/1756-0500-7-670

 received in 2013-07-13, accepted in 2014-09-23,  发布年份 2014

【 摘 要 】

Background

Rhabdomyosarcoma is a soft tissue neoplasm that usually arises in the headand neck region and genitourinary tract. Skin metastasis of rhabdomyosarcoma is extremely rare; of thirteen cases reported in the literature, most were children younger than 10 years and only three cases have been reported in adults.

Case presentation

A 20-year-old Moroccan man was admitted with a right orbital tumor. The tumor was excised and histopathology examination confirmed a diagnosis of rhabdomyosarcoma. The patient was treated with chemotherapy, but local recurrence occurred one year later. The patient underwent right orbital exenteration followed by chemotherapy and radiotherapy. After 6 months, the patient developed a cutaneous mass in the right lumbar region, which was resected. Immunohistochemical examination of the tumor showed this to be a cutaneous metastasis of rhabdomyosarcoma. The patient was treated by chemotherapy and there appeared to be no recurrence after 9 months of follow up.

Conclusions

Skin metastasis from rhabdomyosarcoma is extremely rare, particularly in adults. The purpose of presenting this case report is to raise awareness among clinicians— skin biopsy and immunohistochemistry are needed to distinguish this neoplasm from other cutaneous tumors so that appropriate treatment can be initiated.

【 授权许可】

   
2014 Elomrani et al.; licensee BioMed Central Ltd.

【 图 表 】

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