Extrinsic tooth staining potential of high dose and sustained release iron syrups on primary teeth

BMC Oral Health

Abdullah Saeed Alasmari¹  Hamad Daher Alanazi¹  Abdullah Muhammad Alotain¹  Fahad Murdhi Alenazi¹  Sharat Chandra Pani² 

[1] Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Saudi Arabia;Department of Preventive Dental Sciences, Riyadh 11681, Kingdom of Saudi Arabia

关键词: Primary teeth;    Staining of teeth;    Ferric oxide polymaltose;    Ferrous fumarate;    Oral iron supplement;   

Others  :  1222321
DOI  :  10.1186/s12903-015-0072-0

 received in 2014-11-23, accepted in 2015-07-14,  发布年份 2015

【 摘 要 】

Background

Iron in the form of oral supplements is routinely prescribed to children to help fight anemia, however tooth staining is a commonly reported complication. This study tests in vitro, the staining potential of two different forms of iron syrup on primary teeth.

Methods

Forty caries free primary central incisors were divided into four groups of ten teeth each. The control group comprised of ten teeth immersed in artificial saliva, while the test solutions were comprised of different forms of iron mixed with vitamins such that the iron content of each solution was approximately 100 mg (from 100 to 101.1 mg). The test solutions used iron syrup (Ferrose®, SPIMACO, Jeddah, Saudi Arabia) with iron in the form of ferric oxide polymaltose (FOP), slow release formula (Ferroglobin®, Vitabiotics ltd., London, UK) containing ferrous fumarate (FF and a combination of the two (FOP + FF). All the teeth were then immersed for 72 h and subjected to a protocol developed by Lee et al. to test staining. Color changes were measured using a wave dispersion spectro-photometer (Color-Eye 7000A, X-Rite Gmbh, Regensdorf, Switzerland) on the exposed labial surface at 4, 8, 24, 48 and 72 h. Two-way ANOVA with Scheffe’s post hoc test was used to determine significance of difference in shade, while the Kurskull-Wallis test used to determine the significance of difference in clinical staining (∆E > 3).

Results

While all three iron groups showed some amount of staining, the combination of the two forms of iron (FOP+FF) showed significantly lower incidence of clinical staining than the other two groups at the end of 72 h. At the end of 72 h the (FOP) had significantly higher ∆E than ferrrous fumarate (FF ) while the combination (FOP+ FF) had a significantly lower ∆E than either group.

Conclusion

In an in vitro model, combining different forms of iron seems to elicit a lower intensity of staining than equivalent doses of a single form of iron.

【 授权许可】

   
2015 Pani et al.

【 图 表 】

Fig. 1.

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