Efficacy of a combined contraceptive regimen consisting of condoms and emergency contraception pills

BMC Public Health

Yi-Ran Li¹  Hong-Lei Ji¹  Ying Zhou¹  Yu-Yan Li¹  Jun-Qing Wu¹  Rui Zhao¹ 

[1] National Laboratory of Contraceptives and Devices Research of China, Shanghai 200032, China

关键词: Women;    Cumulative life table rates;    Pregnancy rates;    Methods;    Contraception;   

Others  :  1131567
DOI  :  10.1186/1471-2458-14-354

 received in 2013-12-05, accepted in 2014-04-07,  发布年份 2014

【 摘 要 】

Background

To evaluate and compare the effectiveness of the combined regimen (consisting of condoms and emergency contraception pills (ECP)) and using condoms only for the purpose of preventing pregnancy.

Methods

One-thousand-five-hundred-and-sixty-two (1,562) couples as volunteers enrolled at nine centers in Shanghai. Eight-hundred-and-twelve (812) were randomized to use male condoms and ECP (i.e., Levonorgestrel) as a back-up to condoms (the intervention group) and 750 to use male condoms only(the control group), according to their working unit. Participants were visited at admission and at the end of 1, 3, 6, 9, and 12 months. The cumulative life table rates were calculated for pregnancy and other reasons for discontinuation.

Result

The gross cumulative life table rates showed that the cumulative discontinuation rates for all reasons during the year of follow-up in the condoms plus emergency contraception group and the condoms only group were 7.76 ± 0.94 and 6.61 ± 0.91, respectively, per 100 women (χ2 = 0.41, p = 0.5227). The cumulative gross pregnancy rate of the condoms plus emergency contraception group and the condoms only group were 2.17 ± 0.52 and 1.25 ± 0.41, respectively, per 100 women (χ2 = 1.93, p = 0.1645). The Pearl Index in the condoms plus emergency contraception group and the condoms only group were 2.21% and 1.26%, respectively.

Conclusion

Male condoms remain a highly effective contraceptive method for a period of one year while consistently and correctly used. In addition, the lowest pregnancy rate followed from perfect use condom.

【 授权许可】

   
2014 Zhao et al.; licensee BioMed Central Ltd.

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