期刊论文详细信息
BMC Musculoskeletal Disorders
Massive heterotopic ossification associated with late deficits in posterior wall of acetabulum after failed acetabular fracture operation
Chuncai Zhang1  Shuogui Xu1  Yang Xie1  Yuntong Zhang1 
[1] Department of orthopaedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
关键词: Acetabular fracture;    Acetabulum;    Posterior wall;    Late bone defects;    Heterotopic ossification;   
Others  :  1128990
DOI  :  10.1186/1471-2474-14-368
 received in 2013-02-27, accepted in 2013-12-17,  发布年份 2013
PDF
【 摘 要 】

Background

Heterotopic ossification is a common postoperative complication of acetabular fracture. However, functionally significant heterotopic ossification with associated late bone defects in the posterior wall of the acetabulum is rare and challenging to treat. When heterotopic ossification is a late complication of failed acetabular fracture operation, it is disabling and may only be treated by THA. THA is highly susceptible to premature failure in young and active patients and may require numerous revisions.

Case presentation

This article describes a 40-year-old man with massive heterotopic ossification associated with late bone defects in the posterior wall of the acetabulum after a failed acetabular fracture operation. The primary fracture type was a 62-A2.3 fracture according to the AO/OTA Classification.Surgical excision and anatomical reconstruction of the acetabular wall using heterotopic ossific bone were performed 10 months after the fracture repair. Postoperatively, indomethacin was administered for prophylaxis against recurrence of heterotopic ossification, and hip range of motion was progressively increased. At 5 years and 6 months follow-up, the patient’s pain was relieved and hip function had recovered. Though radiography and CT showed minimal subchondral cysts and mild joint-space narrowing, there was no evidence of graft resorption, progressive posttraumatic osteoarthritis or necrosis of the femoral head.

Conclusion

To the authors’ knowledge, this is the first case of such a challenging condition. Although it is an extremely rare case, it provides an attractive option for avoiding THA, as the long-term follow-up shows a satisfactory outcome.

【 授权许可】

   
2013 Zhang et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150225165914474.pdf 1791KB PDF download
Figure 11. 96KB Image download
Figure 10. 91KB Image download
Figure 9. 78KB Image download
Figure 8. 151KB Image download
Figure 7. 119KB Image download
Figure 6. 184KB Image download
Figure 5. 120KB Image download
Figure 4. 91KB Image download
Figure 3. 72KB Image download
Figure 2. 72KB Image download
Figure 1. 67KB Image download
【 图 表 】

Figure 1.

Figure 2.

Figure 3.

Figure 4.

Figure 5.

Figure 6.

Figure 7.

Figure 8.

Figure 9.

Figure 10.

Figure 11.

【 参考文献 】
  • [1]Daum WJ, Scarborough MT, Gordon W, et al.: Heterotopic ossification and other perioperative complications of acetabular fractures. J Orthop Traumatol 1992, 6:427-432.
  • [2]Burd TA, Lowry KJ, Anglen JO: Indomethacin compared with localized irradiation for the prevention of heterotopic ossification following surgical treatment of acetabular fractures. J Bone Joint Surg Am 2001, 83-A:1783-1788.
  • [3]Cohn RM, Schwarzkopf R, Jaffe F: Heterotopic ossification after total hip arthroplasty (THA). Am J Orthop 2011, 40:E232-E235.
  • [4]Wick M, Müller EJ, Hahn MP, et al.: Surgical excision of heterotopic bone after hip surgery followed by oral indomethacin application: is there a clinical benefit for the patient? Arch Orthop Trauma Surg 1999, 119:151-155.
  • [5]Cobb TK, Berry DJ, Wallrichs SL, et al.: Functional outcome of excision of heterotopic ossification after total hip arthroplasty. Clin Orthop Relat Res 1999, 361:131-139.
  • [6]Liu XW, Xu SG, Zhang CC, Su JC: Application of a shape-memory alloy internal fixator for treatment of acetabular fractures with a follow-up of two to nine years in China. Int Orthop 2009, 34:1033-1041.
  • [7]Zhang CC, Xu SG, Wang JL, et al.: Design and clinical applications of acetabular tridimensional memory alloy-fixation system. Chin J Orthop 2002, 22:709-713.
  • [8]Liu XW, Xu SG, Zhang CC, et al.: Biomechanical study of posterior wall acetabular fracture fixation using acetabular tridimensional memory alloy-fixation system. Clini Biomech 2010, 25:312-317.
  • [9]Sumner DR, Turner TM, Igloria R, et al.: Functional adaptation and ingrowth of bone vary as a function of hip implant stiffness. J Biomech 1998, 31:909-917.
  • [10]Nauth A: Heterotopic ossification in orthopaedic trauma. J Orthop Trauma 2012, 26:684-688.
  • [11]MacFarlane RJ, Ng BH, Gamie Z, et al.: Pharmacological treatment of heterotopic ossification following hip and acetabular surgery. Expert Opin Pharmacother 2008, 9:767-786.
  • [12]Zeckey C, Hildebrand F, Frink M, Krettek C: Heterotopic ossification following implant surgery - epidemiology, therapeutical approaches, and current concepts. Semin Immunopathol 2011, 33:273-286.
  • [13]Baird EO, Kang QK: Prophylaxis of heterotopic ossification - an updated review. J Orthop Surg Res 2009, 4:12. BioMed Central Full Text
  • [14]Blokhuis TJ, Frölke JP: Is radiation superior to indomethacin to prevent heterotopic ossification in acetabular fractures? A systematic review. Clin Orthop Relat Res 2009, 467:526-530.
  • [15]Karunakar MA, Sen A, Bosse MJ, Sims SH, Goulet JA, Kellam JF: Indomethacin as prophylaxis for heterotopic ossification after the operative treatment of fractures of the acetabulum. J Bone Joint Surg Br 2006, 88:1613-1617.
  • [16]Sean MG, Stephen HS, Madhav AK, et al.: Heterotopic Ossification Rates After Acetabular Fracture Surgery Are Unchanged Without Indomethacin Prophylaxis. Clin Orthop Relat Res 2013, 471:2776-2782.
  • [17]Bellabarba C, Berger RA, Bentley CD, et al.: Cementless acetabular reconstruction after acetabular fracture. J Bone Joint Surg Am 2001, 83A:868-876.
  • [18]Giannoudis PV, Grotz MR, Papakostidis C, Dinopoulos H: Operative treatment of displaced fractures of the acetabulum. A meta-analysis. J Bone Joint Surg Br 2005, 87:2-9.
  • [19]Mears DC, Velyvis JH: Primary total hip arthroplasty after acetabular fracture. Instr Course Lect 2001, 50:335-354.
  • [20]Sen RK, Tripathy SK, Aggarwal S, Tamuk T: Posterior wall reconstruction using iliac crest strut graft in severely comminuted posterior acetabular wall fracture. Int Orthop 2011, 35:1223-1228.
  • [21]Daum WJ: Traumatic posterior acetabular defects reconstructed with iliac crest autograft. A report of two cases. Clin Orthop Relat Res 1993, 291:188-192.
  • [22]Zha GC, Sun JY, Chen L, et al.: Late reconstruction of posterior acetabular wall fractures using iliac crest. J Trauma 2012, 72:1386-1392.
  文献评价指标  
  下载次数:121次 浏览次数:6次