Biological and other health related correlates of long-term life dissatisfaction burden

BMC Psychiatry

Heli Koivumaa-Honkanen¹  Heimo Viinamäki²  Tarja Saharinen⁶  Kirsi Honkalampi³  Jukka Hintikka⁴  Soili M Lehto²  Teemu Rissanen⁵ 

[1] Department of Psychiatry, SOTE, Iisalmi, Finland;School of Clinical Medicine, Psychiatry, University of Eastern Finland, Kuopio, Finland;School of Educational Sciences and Psychology, University of Eastern Finland, Joensuu, Finland;Institute of Clinical Medicine, Psychiatry, University of Tampere, Tampere, Finland;Department of Psychiatry, Päijät-Häme Central Hospital, Lahti, Finland;Department of Psychiatry, Kuopio University Hospital, P.O.B. 1777,FI-70211, Kuopio, Finland

关键词: Metabolic syndrome;    Adiponectin;    Inflammation;    Social support;    Burden;    Life satisfaction;   

Others  :  1123991
DOI  :  10.1186/1471-244X-13-202

 received in 2012-10-09, accepted in 2013-07-31,  发布年份 2013

【 摘 要 】

Background

Mental health is interconnected with somatic health and can manifest itself in biological processes. Life dissatisfaction is an indicator of subjective well-being, but information on its biological correlates is scarce. The aim of this study was to investigate the biological correlates along with other health-related factors of long-term life dissatisfaction in a population-based sample.

Methods

As part of the Kuopio Depression Study, health questionnaires were sent to a randomly selected population-based sample in 1998, 1999, and 2001. In 2005, among a clinically studied sub-sample (n = 305), the 7-year long-term life dissatisfaction burden was assessed by summing life satisfaction scores from previous health questionnaires. Several sociodemographic, health, health behavior, and biological factors were investigated in respect to their associations to categorized (low and high) and continuous (linear regression) life satisfaction burden score (higher values indicating dissatisfaction).

Results

In the final linear regression model long-term life dissatisfaction burden was significantly associated with poor social support (B = 0.138; p < 0.001), marital status (i.e. living alone) (B = 0.049; p = 0.019), current smoking (B = 0.087; p < 0.001), poor sleep (B = 0.052; p = 0.001), use of statins (B = −0.052; p = 0.002) and lower serum adiponectin level (B = −0.001; p = 0.039) whereas association of metabolic syndrome was marginally nonsignificant (B = 0.029; p = 0.055).

Conclusion

Long-term life dissatisfaction is associated with adverse health, health behavioral, and social factors, as well as with a decreased anti-inflammatory buffer capacity, all indicating close relationships between subjective well-being and somatic morbidity.

【 授权许可】

   
2013 Rissanen et al.; licensee BioMed Central Ltd.

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