Personalized medicine and atrial fibrillation: will it ever happen?

BMC Medicine

Patrick T Ellinor¹  Steven A Lubitz¹ 

[1]Cardiovascular Research Center and Cardiac Arrhythmia Service, Massachusetts General Hospital, 149 13th Street, 4th Floor, Charlestown, MA 02129, USA

关键词: pharmacogenetics;    risk prediction;    personalized medicine;    genetics;    Atrial fibrillation;   

Others  :  857270
DOI  :  10.1186/1741-7015-10-155

 received in 2012-07-24, accepted in 2012-12-04,  发布年份 2012

【 摘 要 】

Atrial fibrillation (AF) is a common arrhythmia of substantial public health importance. Recent evidence demonstrates a heritable component underlying AF, and genetic discoveries have identified common variants associated with the arrhythmia. Ultimately one hopes that the consideration of genetic variation in clinical practice may enhance care and improve health outcomes. In this review we explore areas of potential clinical utility in AF management including those relating to pharmacogenetics and risk prediction.

【 授权许可】

   
2012 Lubitz and Ellinor; licensee BioMed Central Ltd.

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