期刊论文详细信息
BMC Oral Health
Does post-bleaching fluoridation affect the further demineralization of bleached enamel? An in vitro study
Zeynep Ergücü1  Hüseyin Tezel1  Hande Kemaloğlu1 
[1] Department of Restorative Dentistry, Faculty of Dentistry, Ege University, Bornova 35100, Izmir, Turkey
关键词: Titanium tetrafluoride;    Sodium fluoride;    Demineralization;    Bleaching;   
Others  :  1091865
DOI  :  10.1186/1472-6831-14-113
 received in 2014-05-05, accepted in 2014-08-29,  发布年份 2014
PDF
【 摘 要 】

Background

Topical fluoride agents have been shown to be the most effective method in treating demineralized enamel after in-office bleaching treatments. Thus, this study aimed to examine the effects of two different post-bleaching fluoridation agents: 1.5% titanium tetrafluoride (TiF4) (9200 ppm) and 2.1% sodium fluoride (NaF) (9500 ppm), on the calcium loss of enamel after an acidic challenge.

Methods

Ten maxillary premolars were sectioned into four pieces and then divided into the following four groups: Group 1: Control, kept in artificial saliva, no treatment; Group 2: 38% hydrogen peroxide (HP); Group 3: 38% HP followed by 1.5% TiF4; Group 4: 38% HP followed by 2.1% NaF solution. The specimens were subjected to demineralization for 16 days, refreshing the solution every 4 days; that is, on the 4th, 8th, 12th, and 16th days. Calcium ion (Ca2+) concentration was determined by an atomic absorption spectrophotometer. Data were analyzed using Friedman and Wilcoxon tests (p = 0.05).

Results

The loss of Ca2+ in each of the test groups was compared with that of the control group, depicting that there was a statistically significant difference among the groups after 4, 8, 12, and 16 days and in total (p < 0.05). The calcium released from the fluoride-applied groups was lower when compared with the 38% HP and control group. At the end of the 16th day, the total amount of calcium released from the TiF4-treated samples (9.12 mg/mL) was less than from the NaF-treated samples (13.67 mg/mL) (p < 0.05).

Conclusions

Regarding the results of our in vitro study, the risk of further demineralization was significantly reduced with the use of TiF4 and NaF after bleaching with 38% HP. TiF4was found to be more effective in preventing Ca2+ release owing to acid attack when compared with NaF. In the case of an intra-oral acidic exposure, the use of topical 1.5% TiF4 and 2.1% NaF agents might be beneficial after bleaching with 38% HP.

【 授权许可】

   
2014 Kemaloğlu et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150128174817599.pdf 795KB PDF download
Figure 2. 41KB Image download
Figure 1. 66KB Image download
【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】
  • [1]Rotstein I, Dankner E, Goldman A, Heling I, Stabholz A, Zalkind M: Histochemical analysis of dental hard tissues following bleaching. J Endod 1996, 22:23-25.
  • [2]Lewinstein I, Fuhrer N, Churaru N, Cardash H: Effect of different peroxide bleaching regimens and subsequent fluoridation on the hardness of human enamel and dentin. J Prosthet Dent 2004, 92:337-342.
  • [3]Al-Salehi SK, Wood DJ, Hatton PV: The effect of 24 h non-stop hydrogen peroxide concentration on bovine enamel and dentine mineral content and microhardness. J Dent 2007, 35:845-850.
  • [4]Tezel H, Ertas OS, Ozata F, Dalgar H, Korkut ZO: The effect of bleaching agents calcium loss on enamel surface. Quintessence Int 2007, 38:339-347.
  • [5]Pinto CF, Oliveira R, Cavalli V, Giannini M: Peroxide bleaching agent effects on enamel surface microhardness, roughness and morphology. Braz Oral Res 2004, 18:306-311.
  • [6]Chen HP, Chang CH, Liu JK, Chuang SF, Yang JY: Effect of fluoride containing bleaching agents on enamel surface properties. J Dent 2008, 36:718-725.
  • [7]Ushigome TS, Takemoto M, Hattori M, Yoshinari E, Kawada , Oda Y: Influence of peroxide treatment on bovine enamel surface—Cross-sectional analysis. Dent Mater J 2009, 28:315-323.
  • [8]Arends J, Christoffersen J, Christoffersen MR, Schuthof J: Influence of fluoride concentration on progress of demineralization in bovine enamel at pH 4.5. Caries Res 1983, 17:455-457.
  • [9]Attin T, Kielbassa AM, Schwanenberg M, Hellwig E: Effect of fluoride treatment on remineralization of bleached enamel. J Oral Rehab 1997, 24:282-286.
  • [10]Attin T, Kocabiyik M, Buchalla W, Hannig C, Becker K: Susceptibility enamel surfaces to demineralization after application of fluoridated carbamide peroxide gels. Caries Res 2003, 37:93-99.
  • [11]Bizhang M, Seemann R, Duve G, Römhild G, Altenburger JM, Jahn KR, Zimmer S: Demineralization effects of 2 bleaching procedures on enamel surfaces with and withoutpost-treatment fluoride application. Oper Dent 2006, 31:705-709.
  • [12]Shrestha BM, Mundorff SA, Bibby BG: Enamel Dissolution: I Effects of Various Agents and Titanium Tetrafluoride. J Dent Res 1972, 5:1561-1566.
  • [13]Büyükyilmaz T, Sen BH, Ogaard B: Retention of titanium tetrafluoride (TiF4), used as fissure sealant on human deciduous molars. Acta Odontol Scand 1997, 55:73-78.
  • [14]Eisenburger M, Addy M, Hughes JA, Shellis RP: Effect of time on the remineralization of enamel by synthetic saliva after citric acid erosion. Caries Res 2001, 35:211-215.
  • [15]Lippert F, Parker DM, Jandt KD: Toothbrush abrasion of surface softened enamel studied with tapping mode AFM and AFM nanoindentation. Caries Res 2004, 38:464-472.
  • [16]Tezel H, Ergücü Z, Önal B: Effects of topical fluoride agents on artificial enamel lesion formation in vitro. Quintessence Int 2002, 33:347-352.
  • [17]Lewinstein I, Hirschfeld Z, Stabholz A, Rotstein I: Effect of hydrogen peroxide and sodium perboride on the microhardness of human enamel and dentin. J Endod 1994, 20:61-63.
  • [18]Wiegand A, Attin T: Influence of fluoride on the prevention of erosive lesions–a review. Oral Health Prev Dent 2003, 1:245-253.
  • [19]Rølla G, Saxegaard E: Critical evaluation of the composition and use of topical fluorides with the emphasis on the role of calcium fluoride in caries inhibition. J Dent Res 1990, 69:780-785.
  • [20]Al-Qunaian TA: Microhardness of intracoronal dentin exposed to bleaching enamel. Oper Dent 2005, 30:265-270.
  • [21]Skartveit L, Tveit AB, Tøtdal B, Selvig KA: Effects of TiF4 solutions on root surfaces in vitro after different application periods. Acta Odontol Scand 1989, 47:25-30.
  • [22]Mundorff SA, Little MF, Bibby BG: Enamel dissolution: II. Action of titanium tetrafluoride. J Dent Res 1972, 51:1567-1571.
  • [23]Attin T, Deifuss H, Hellwig E: Influence of acidified fluoride gel on abrasion resistance of eroded enamel. Caries Res 1999, 33:135-139.
  • [24]Tveit AB, Hals E, Isrenn R, Totdal B: Highly acid SnF2 and TiF4 solutions. Caries Res 1983, 17:412-418.
  • [25]van Rijkom H, Ruben J, Vieira A, Huysmans MC, Truin GJ, Mulder J: Erosion-inhibiting effect of sodium fluoride and titanium tetrafluoride treatment in vitro. Eur J Oral Sci 2003, 111:253-257.
  • [26]Øgaard B: Effects of fluoride on caries development and progression in vivo. J Dent Res 1990, 69:813-819.
  • [27]Attin T, Albrecht K, Becker K, Hannig C, Wiegand A: Influence of carbamide peroxide on enamel fluoride uptake. J Dent 2006, 34:668-675.
  • [28]Arnold WH, Haase A, Hacklaender J, Gintner Z, Bánóczy J, Gaengler P: Effect of pH of amine fluoride containing toothpastes on enamel remineralization in vitro. BMC Oral Health 2007, 17:7-14.
  • [29]Burgmaier GM, Schultze IM, Attin T: Fluoride uptake and development of artificial erosions in bleached and fluoridated enamel in vitro. J Oral Rehabil 2002, 29:799-804.
  • [30]Willis JB: Determination of calcium and magnesium in urine by atomic absorbtion spectroscopy. Anal Chem 1961, 33:556-559.
  • [31]Trudeau DL, Freier EF: Determination of calcium in urine an serum by atomic absorption spectrophotometry (AAS). Clin Chem 1967, 13:101-114.
  • [32]Grenby TH, Mistry M, Desai T: Potential dental effects of infants’ fruit drinks studied in vitro. Br J Nutr 1990, 64:273-283.
  • [33]Hara AT, Zero DT: Analysis of the erosive potential of calcium-containing acidic beverages. Eur J Oral Sci 2008, 116:60-65.
  • [34]Schlueter N, Hara A, Shellis RP, Ganss C: Methods for the measurement and characterization of erosion in enamel and dentine. Caries Res 2011, 45(suppl):13-23.
  文献评价指标  
  下载次数:30次 浏览次数:28次