BamBam: genome sequence analysis tools for biologists

BMC Research Notes

Joshua A Udall²  Mark D Huynh²  Zachary S Liechty²  Justin T Page¹ 

[1] Department of Biology, Brigham Young University, Provo, UT 84602, USA;Department of Plant and Wildlife Science, Brigham Young University, Provo, UT 84602, USA

关键词: Expression;    Methylation;    Consensus;    Indel;    SNP;    Haplotype;    BAM;    SAM;   

Others  :  1118330
DOI  :  10.1186/1756-0500-7-829

 received in 2014-08-28, accepted in 2014-10-24,  发布年份 2014

【 摘 要 】

Background

Massive computational power is needed to analyze the genomic data produced by next-generation sequencing, but extensive computational experience and specific knowledge of algorithms should not be necessary to run genomic analyses or interpret their results.

Findings

We present BamBam, a package of tools for genome sequence analysis. BamBam contains tools that facilitate summarizing data from BAM alignment files and identifying features such as SNPs, indels, and haplotypes represented in those alignments.

Conclusions

BamBam provides a powerful and convenient framework to analyze genome sequence data contained in BAM files.

【 授权许可】

   
2014 Page et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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