Metachronous isolated breast metastasis from pulmonary adenocarcinoma with micropapillary component causing diagnostic challenges

BMC Cancer

Sung Hwa Bae¹  Sung Min Kang²  Sung Hwan Park⁴  Hoon Kyu Oh³  Jin Gu Bong⁴  Young Ju Jeong⁴ 

[1]Department of Internal Medicine, Catholic University of Daegu School of Medicine, (705-718) 33, Duryugongwon-ro 17-gil, Nam-gu, Daegu, Korea

[2]Department of Nuclear medicine, Catholic University of Daegu School of Medicine, 33, Duryugongwon-ro 17-gil, Nam-gu, Daegu, Korea

[3]Department of Pathology, Catholic University of Daegu School of Medicine, 33, Duryugongwon-ro 17-gil, Nam-gu, Daegu, Korea

[4]Department of Surgery, Catholic University of Daegu School of Medicine, 33, Duryugongwon-ro 17-gil, Nam-gu, Daegu, Korea

关键词: Lung cancer;    Micropapillary component;    Pulmonary adenocarcinoma;    Breast metastasis;   

Others  :  1121004
DOI  :  10.1186/1471-2407-14-736

 received in 2014-07-15, accepted in 2014-09-26,  发布年份 2014

【 摘 要 】

Background

Breast metastasis from extramammary malignancy is uncommon and often presents diagnostic challenges. Herein, we report a case of a patient with metachronous isolated breast metastasis from pulmonary adenocarcinoma with micropapillary component.

Case presentation

A 47-year-old woman presented with left breast nodule detected on a screening breast ultrasonography. She had surgery for pulmonary adenocarcinoma 3 years ago, and was disease-free state in the follow up studies. The patient was diagnosed with invasive micropapillary carcinoma of the breast by core needle biopsy. She underwent left breast lumpectomy and sentinel lymph node biopsy, and the histologic findings revealed micropapillary carcinoma. Based on the immunohistochemical study, the final diagnosis was solitary breast metastasis from pulmonary adenocarcinoma with micropapillary component.

Conclusions

The diagnosis of metastasis to the breast from extramammary malignancies is difficult but important for proper management and prediction of prognosis. A careful clinical history with a thorough clinical examination is needed to make the correct diagnosis.

【 授权许可】

   
2014 Jeong et al.; licensee BioMed Central Ltd.

【 图 表 】

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