期刊论文详细信息
BMC Research Notes
Sagace: A web-based search engine for biomedical databases in Japan
Kenji Mizuguchi2  Tohru Masui1  Ryuichi Sakate1  Yuki Sakaguchi1  Chioko Nagao2  Yi-An Chen2  Maori Ito2  Yoshinobu Igarashi2  Mizuki Morita2 
[1] Department of Disease Bioresources Research, National Institute of Biomedical Innovation, 7-6-8 Saito Asagi, Ibaraki, Osaka, Japan;Department of Fundamental Research, National Institute of Biomedical Innovation, 7-6-8 Saito Asagi, Ibaraki, Osaka, Japan
关键词: Microdata;    Faceted search;    Biomedical resources;    Biomedical data;    Search engine;   
Others  :  1165334
DOI  :  10.1186/1756-0500-5-604
 received in 2012-06-11, accepted in 2012-10-19,  发布年份 2012
PDF
【 摘 要 】

Background

In the big data era, biomedical research continues to generate a large amount of data, and the generated information is often stored in a database and made publicly available. Although combining data from multiple databases should accelerate further studies, the current number of life sciences databases is too large to grasp features and contents of each database.

Findings

We have developed Sagace, a web-based search engine that enables users to retrieve information from a range of biological databases (such as gene expression profiles and proteomics data) and biological resource banks (such as mouse models of disease and cell lines). With Sagace, users can search more than 300 databases in Japan. Sagace offers features tailored to biomedical research, including manually tuned ranking, a faceted navigation to refine search results, and rich snippets constructed with retrieved metadata for each database entry.

Conclusions

Sagace will be valuable for experts who are involved in biomedical research and drug development in both academia and industry. Sagace is freely available athttp://sagace.nibio.go.jp/en/ webcite.

【 授权许可】

   
2012 Morita et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150416030003966.pdf 1026KB PDF download
Figure 2. 100KB Image download
Figure 1. 44KB Image download
【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】
  • [1]Galperin MY, Fernández-Suárez XM: The 2012 nucleic acids research database issue and the online molecular biology database collection. Nucleic Acids Res 2012, 40(Database issue):D1-D8.
  • [2]Database Center for Life Science (DBCLS) [http://dbcls.rois.ac.jp/en/] webcite
  • [3]National Bioscience Database Center (NBDC) [http://biosciencedbc.jp/] webcite
  • [4]National Institute of Biomedical Innovation (NIBIO) [http://www.nibio.go.jp/english/] webcite
  • [5]Hearst MA: Search user interfaces. Cambridge University Press; 2009.
  • [6]Hearst MA: Next Generation Web Search: Setting Our Sites. IEEE Data Engineering Bulletin 2000, 23(3):38-48.
  • [7]Microdata [http://www.w3.org/TR/microdata/] webcite
  • [8]RDFa [http://www.w3.org/TR/rdfa-syntax/] webcite
  • [9]Microformats [http://microformats.org/] webcite
  • [10]Schema.org [http://schema.org/] webcite
  • [11]Guha R: Introducing schema.org: Search engines come together for a richer web. [http:/ / googleblog.blogspot.jp/ 2011/ 06/ introducing-schemaorg-search-engine s.html] webciteGoogle Official Blog 2011.
  • [12]Seth S: Introducing schema.org: A Collaboration on Structured Data. [http:/ / www.ysearchblog.com/ 2011/ 06/ 02/ introducing-schema-org-a-collaborat ion-on-structured-data/ ] webciteYahoo! Developer Network Blog 2011.
  • [13]Macbeth S: Introducing Schema.org: Bing, Google and Yahoo Unite to Build the Web of Objects. [http:/ / www.bing.com/ community/ site_blogs/ b/ search/ archive/ 2011/ 06/ 02/ bing-google-and-yahoo-unite-to-buil d-the-web-of-objects.aspx] webciteBing Search Blog 2011.
  • [14]Sagace markup schemas for biological databases [http://sagace.nibio.go.jp/schema/en/schema.html] webcite
  • [15]Japanese Collection of Research Bioresources (JCRB) Cell Bank [http://cellbank.nibio.go.jp/english/] webcite
  • [16]Google Maps [https://Maps.google.com/] webcite
  • [17]Taxonomy icon [http://biosciencedbc.jp/taxonomy_icon/taxonomy_icon.cgi?lng=en] webcite
  • [18]Entrez [http://www.ncbi.nlm.nih.gov/Entrez/] webcite
  • [19]Sayers EW, Barrett T, Benson DA, Bryant SH, Canese K, Chetvernin V, Church DM, DiCuccio M, Edgar R, Federhen S, et al.: Database resources of the national center for biotechnology information. Nucleic Acids Res 2009, 37(Database issue):D5-D15.
  • [20]EB-eye [http://www.ebi.ac.uk/ebisearch/] webcite
  • [21]Valentin F, Squizzato S, Goujon M, McWilliam H, Paern J, Lopez R: Fast and efficient searching of biological data resources–using EB-eye. Brief Bioinform 2010, 11(4):375-384.
  • [22]Hyper Estraier [http://fallabs.com/hyperestraier/] webcite
  • [23]Life Science Database Cross Search [http://biosciencedbc.jp/dbsearch/?lang=en] webcite
  • [24]Eisenberg I, Avidan N, Potikha T, Hochner H, Chen M, Olender T, Barash M, Shemesh M, Sadeh M, Grabov-Nardini G, et al.: The UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase gene is mutated in recessive hereditary inclusion body myopathy. Nat Genet 2001, 29(1):83-87.
  • [25]KEGG [http://www.kegg.jp/] webcite
  • [26]FLJ Human cDNA Database [http://flj.lifesciencedb.jp/] webcite
  • [27]Protein Data Bank Japan (PDBj) [http://www.pdbj.org/] webcite
  • [28]Genome Medicine Database of Japan (GeMDBJ) [https://gemdbj.nibio.go.jp/] webcite
  • [29]Genome Network Project [http://genomenetwork.nig.ac.jp/index_e.html] webcite
  • [30]Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126(4):663-676.
  文献评价指标  
  下载次数:17次 浏览次数:26次