期刊论文详细信息
BMC Research Notes
Acute urticaria as a side effect of the Mirena® (levonorgestrel-releasing intrauterine system): a case report
Haiyan Zhu1  Xueqing Wu1  Xiangjuan Chen1 
[1] Department of Obstetrics and Gynecology, The First Affiliated Hospital of Wenzhou Medical College, 2# Fuxue Road, Wenzhou 325000, People’s Republic of China
关键词: Allergic reactions;    Mirena®;   
Others  :  1134026
DOI  :  10.1186/1756-0500-7-209
 received in 2013-08-25, accepted in 2014-03-21,  发布年份 2014
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【 摘 要 】

Background

The levonorgestrel intrauterine system, Mirena®, is widely used for contraception and the treatment of idiopathic menorrhagia. Here, we reported one case of acute urticaria following Mirena® implantation to increase the awareness of possible adverse side effects associated with Mirena®.

Case presentation

The case presented is a 27-year-old Chinese woman who received Mirena® implantation for her adenomyosis and menorrhagia. The operation was successful and the patient did not experience any discomfort during the operation. However, she developed acute urticaria on her entire body accompanied with pruritic, slight left lower quadrant pain, and slight dizziness two hours after the operation. The patient was recommended to have the Mirena® removed immediately, and she took 10 mg oral methylprednisolone and 5 mg desloratadine tablet daily for five days. Her urticaria resolved and did not recur.

Conclusion

The patient’s acute urticaria seems to have been associated with the Mirena® levonorgestrel intrauterine system implantation, since she had no history of allergic reactions to materials used during the operation such as plastic, metal, alcohol, medications, and povidone-iodine.

【 授权许可】

   
2014 Chen et al.; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Varma R, Sinha D, Gupta JK: Non-contraceptive uses of levonorgestrel-releasing hormone system (LNG-IUS)—a systematic enquiry and overview. Eur J Obstet Gynecol Reprod Biol 2006, 125:9-28.
  • [2]Dubuissona JB, Mugnierb E, the Mirena® Study Groupa: Acceptability of the levonorgestrel-releasing intrauterine system after discontinuation of previous contraception: results of a French clinical study in women aged 35 to 45 years. Contraception 2002, 66:121-128.
  • [3]Rauramo I, Elo I, Istre O: Long-term treatment of menorrhagia with levonorgestrel intrauterine system versus endometrial resection. Obstet Gynecol 2004, 104:1314-1321.
  • [4]Karri K, Mowbray D, Adams S, Rendall JRS: Severe seborrhoeic dermatitis: Side-effect of the Mirena intra-uterine system. Eur J Contracept Reprod Health Care 2006, 11:53-54.
  • [5]Pereira A, Coker A: Hypersensitivity to mirena-a rare complication. J Obstet Gynaecol 2003, 23:81-92.
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