Low dose of continuous – wave microwave irradiation did not cause temperature increase in muscles tissue adjacent to titanium alloy implants – an animal study

BMC Musculoskeletal Disorders

Yuehong Bai¹  Lan Jiang¹  Gang Wang¹  Xianxuan Feng¹  Han Zhang¹  Tengfei Fu¹  Yiming Xu¹  Dongmei Ye¹ 

[1] Department of Rehabilitation, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China

关键词: Temperature;    Implant;    Titanium alloy;    Microwave;   

Others  :  1128998
DOI  :  10.1186/1471-2474-14-364

 received in 2013-06-01, accepted in 2013-12-20,  发布年份 2013

【 摘 要 】

Background

Research studies on the influence of radiofrequency electromagnetic radiation on implants in vitro have failed to investigate temperature changes in the tissues adjacent to the implants under microwave therapy. We therefore, used a rabbit model in an effort to determine the impact of microwave therapy on temperature changes in tissues adjacent to the titanium alloy implants and the safety profile thereof.

Methods

Titanium alloy internal fixation plates were implanted in New Zealand rabbits in the middle of femur. Microwave therapy was performed by a 2450 MHz microwave generator 3 days after the surgery. Temperature changes of muscles adjacent to the implants were recorded under exposure to dose-gradient microwave radiation from 20w to 60w.

Results

Significant difference between control and microwave treatment group at peak temperatures (T_peak) and temperature gap (T_gap= T_peak-T_vally) were observed in deep muscles (T_peak, 41.63 ± 0.21°C vs. 44.40 ± 0.17°C, P < 0.01; T_gap, 5.33 ± 0.21°C vs. 8.10 ± 0.36°C, P < 0.01) and superficial muscles (T_peak, 41.53 ± 0.15°C vs. 42.03 ± 0.23°C, P = 0.04; T_gap, 5.23 ± 0.21°C vs. 5.80 ± 0.17°C, P = 0.013) under 60 w, and deep muscles (T_peak, 40.93 ± 0.25°C vs. 41.87 ± 0.23°C, P = 0.01; T_gap, 4.73 ± 0.20°C vs. 5.63 ± 0.35°C, P = 0.037) under 50w, but not under 20, 30 and 40w.

Conclusion

Our results suggest that low-dose (20w-40w) continuous-wave microwave irradiation delivered by a 2450 MHz microwave generator might be a promising treatment for patients with titanium alloy internal fixation, as it did not raise temperature in muscle tissues adjacent to the titanium alloy implant.

【 授权许可】

   
2013 Ye et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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