Tuberculosis active case finding: uptake and diagnostic yield among minibus drivers in urban South Africa

BMC Public Health

Christopher J Hoffmann²  Gavin J Churchyard⁴  Salome Charalambous³  Gillian Gresak¹  Violet Chihota³  Ephraim Zwane¹  Tonderai Mabuto³ 

[1] The Aurum Institute, Johannesburg, South Africa;Division of Infectious Diseases, Johns Hopkins University School of Medicine, 725 N Wolfe St, Rm 226, Baltimore 21205, Maryland, USA;School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;London School of Hygiene and Tropical Medicine, London, UK

关键词: Cross-sectional;    Active case finding;    Transmission;    Transport;    Operational research;    HIV;    Tuberculosis;   

Others  :  1138426
DOI  :  10.1186/s12889-015-1592-x

 received in 2014-10-24, accepted in 2015-02-27,  发布年份 2015

【 摘 要 】

Background

Tuberculosis (TB) active case finding is a part of TB control in areas of higher TB prevalence. Congested public transportation settings may be areas of increased TB transmission. We evaluated the uptake and diagnostic yield of an active TB screening program among minibus drivers in a large public transportation facility in Johannesburg, South Africa.

Methods

Over an eight month period, we intensively recruited minibus drivers for TB screening with a goal of 80% uptake among the estimated 2000 drivers. All participants were screened for TB symptoms, offered HIV testing, and had sputum collected for smear microscopy and liquid culture.

Results

686 drivers were screened for TB, representing an uptake of only 34% of all drivers (43% of the target screening). Ten drivers (1.5%) were culture positive for TB, nine of whom were sputum smear microscopy negative. Factors associated with previously undiagnosed TB included a history of incarceration (odds ratio [OR] 5.5, 95% confidence interval: 1.1, 27.3) and HIV positivity (OR 5.3, 95% confidence interval: 1.1, 26.3).

Conclusions

We identified undiagnosed pulmonary TB cases among drivers but at a level that may be insufficient to justify systematic case finding in this population considering the poor uptake.

【 授权许可】

   
2015 Mabuto et al.; licensee BioMed Central.

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