Management of infants born to women infected with hepatitis B in the military healthcare system

BMC Research Notes

LoRanée Braun²  Mark W Burnett¹  Dawn F Muench²  Elizabeth G Simmons²  Rebecca J Sainato¹ 

[1] Department of Pediatrics, Tripler Army Medical Center, Honolulu, HI 96859-5000, USA;Department of Pediatrics, Madigan Healthcare System, Tacoma, WA, USA

关键词: Newborns;    Military;    Hepatitis B vaccines;    Hepatitis B;    HBIG;    Electronic health records;   

Others  :  1141802
DOI  :  10.1186/1756-0500-6-338

 received in 2013-01-23, accepted in 2013-08-28,  发布年份 2013

【 摘 要 】

Background

Hepatitis B virus (HBV) is endemic worldwide. Given significant rates of infectivity, all infants born to Hepatitis B surface antigen positive mothers need to receive treatment at birth, immunization and post-vaccination serologic testing. However, not all infants complete these requirements.

Findings

We performed a retrospective review of the management of infants born to Hepatitis B infected mothers at two large military hospitals in the United States that use a global electronic medical record to track patient results. We then compared these results to those recently published by the National Perinatal Hepatitis B Prevention Program (PHBPP), which does not include hospitals in the United States Military Healthcare System. Our results show that although all infants were managed appropriately at birth and immunization rates were very high, post vaccination follow-up testing rates were much lower than those seen in centers participating in the PHBPP. The rates of post vaccination serological testing were significantly higher for infants born to Hepatitis B e antigen positive mothers and those referred to a pediatric infectious disease specialist.

Conclusions

Despite use of a global electronic medical record in the United States Military Healthcare System, management of HBV-exposed infants does not always follow recommended guidelines. These infants could benefit from a more systematic method of follow-up, similar to the PHBPP, to ensure HBV serologic testing is obtained after the vaccination series is complete.

【 授权许可】

   
2013 Sainato et al.; licensee BioMed Central Ltd.

【 参考文献 】

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