BMC Geriatrics | |
Mortality of older persons living alone: Singapore Longitudinal Ageing Studies | |
Ngan Phoon Fong1  Lei Feng1  Khuan Yew Chow3  Ma Shwe Zin Nyunt1  Liang Feng1  Aizhen Jin3  Tze Pin Ng2  | |
[1] Department of Psychological Medicine, Gerontology Research Programme, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore;Department of Psychological Medicine, Gerontology Research Programme, National University of Singapore, NUHS Tower Block, 9th Floor, 1E Kent Ridge Road, Singapore 119228, Singapore;National Registry of Diseases Office (NRDO), Health Promotion Board, Singapore, Singapore | |
关键词: Mortality; Health status; Living alone; Ageing; | |
Others : 1231970 DOI : 10.1186/s12877-015-0128-7 |
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received in 2015-03-30, accepted in 2015-10-12, 发布年份 2015 | |
【 摘 要 】
Background
We investigated the association of living alone with mortality among older persons, independently of marital, health and other factors, and explored its effect modification by age group, sex, marital status and physical functional disability.
Method
Using data from 8 years of mortality follow up (1 September 2003 to 31 December 2011) of 2553 participants in the Singapore Longitudinal Ageing Studies (SLAS) cohort, we estimated hazard ratio (HR) of mortality associated with living alone using Cox proportional hazard models.
Results
At baseline, 7.4 % (N = 189) of the participants were living alone, and 227 (8.9 %) died during the follow up period. Living alone was significantly associated with mortality 1.66 (95 % CI, 1.05–2.63), controlling for health status (hypertension, diabetes, chronic lung disease, stroke, heart disease, kidney failure, IADL–ADL disability and depressive symptoms), marital status and other variables (age, sex, housing type). Possible substantive effect modification by sex (p for interaction = 0.106) and marital status (p for interaction <0.115) were observed: higher among men (HR = 2.36, 95 % CI, 1.24–4.49) than women (HR = 1.14, 95 % CI, 0.58–2.22), and among single, divorce or widowed (HR = 2.26, 95 % CI, 1.24–4.10) than married individuals (HR = 0.83, 95 % CI, 0.30–2.31).
Conclusion
Living alone was associated with increased mortality, independently of marital, health and other variables. The impact of living alone on mortality appeared to be stronger among men and those who were single, divorced or married.
【 授权许可】
2015 Ng et al.
【 预 览 】
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【 参考文献 】
- [1]Tomassini C, Glaser K, Wolf DA, van Groenou MIB, Grundy E: Living arrangement among older people: overview of trends in Europe and the USA. Population Trends 2004, 115:24-34.
- [2]Martin LA: Changing intergenerational family relations in East Asia. Ann Am Acad Pol Soc Sci 1990, 510:102-114.
- [3]Frasure-Smith N, Lespérance F, Gravel G, Masson A, Juneau M, Talajic M, Bourassa MG: Social support, depression, and mortality during the first year after myocardial infarction. Circulation 2000, 101(16):1919-24.
- [4]Kop WJ, Berman DS, Gransar H, Wong ND, Miranda-Peats R, White MD, et al.: Social network and coronary artery calcification in asymptomatic individuals. Psychosom Med 2005, 67(3):343-52.
- [5]Hirdes JP, Forbes WF: The importance of social relationships, socioeconomic status and health practices with respect to mortality among healthy Ontario males. J Clin Epidemiol 1992, 45(2):175-182.
- [6]Rees CA, Karter AJ, Young BA: Race/ethnicity, social support, and associations with diabetes self–care and clinical outcomes in NHANES. Diabetes Educ 2010, 36(3):435-445.
- [7]Rodriguez CJ, Elkind MS, Clemow L, Jin Z, Di Tullio M, et al.: Association between social isolation and left ventricular mass. Am J Med 2011, 124(2):164-70.
- [8]Christakis NA, Fowler JH: The spread of obesity in a large social network over 32 years. N Engl J Med 2007, 357(4):370-379.
- [9]Lund R, Due P, Modvig J, Holstein BE, Damsgaard MT, Andersen PK: Cohabitation and marital status as predictors of mortality––an eight year follow–up study. Soc Sci Med 2002, 55(4):673-9.
- [10]Koskinen S, Joutsenniemi K, Martelin T, Martikainen P: Mortality differences according to living arrangements. Int J Epidemiol 2007, 36(6):1255-64.
- [11]Crockett AJ, Cranston JM, Moss JR, Alpers JH: The impact of anxiety, depression and living alone in chronic obstructive pulmonary disease. Qual Life Res 2002, 11(4):309-16.
- [12]Börü UT, Oztürk E, Taşdemir M, Sur H: Living alone following first–ever stroke: a prospective study in Turkey identifying the risk factors and evaluating their effects. N Z Med J 2007, 120(1255):U2559.
- [13]Herttua K, Martikainen P, Vahtera J, Kivimäki M: Living alone and alcohol–related mortality: a population–based cohort study from Finland. PLoS Med 2011., 8(9) Article ID e1001094
- [14]Holwerda TJ, Beekman AT, Deeg DJ, Stek ML, van Tilburg TG, Visser PJ, et al. Increased risk of mortality associated with social isolation in older men: only when feeling lonely? Results from the Amsterdam Study of the Elderly (AMSTEL). Psychol Med. 2012;42(4):843–53.
- [15]Schmaltz HN, Southern D, Ghali WA, Jelinski SE, Parsons GA, King KM, et al. Living alone, patient sex and mortality after acute myocardial infarction. J Gen Intern Med. 2007;22(5):572–8.
- [16]Case RB, Moss AJ, Case N, McDermott M, Eberly S: Living alone after myocardial infarction. Impact on prognosis. JAMA 1992, 267(4):515-9.
- [17]Udell JA, Steg PG, Scirica BM, Smith SC Jr, Ohman EM, Eagle KA, Goto S, Cho JI, Bhatt DL: REduction of Atherothrombosis for Continued Health (REACH) Registry Investigators: Living alone and cardiovascular risk in outpatients at risk of or with atherothrombosis. Arch Intern Med 2012, 172(14):1086-95.
- [18]Gopinath B, Rochtchina E, Anstey KJ, Mitchell P. Living alone and risk of mortality in older, community–dwelling adults. JAMA Intern Med. 2013;173(4):320–1.
- [19]Perissinotto CM, Stijacic Cenzer I, Covinsky KE: Loneliness in older persons: a predictor of functional decline and death. Arch Intern Med 2012, 172(14):1078-83.
- [20]Davis MA, Neuhaus JM, Moritz DJ, Segal MR: Living arrangements and survival among middle–aged and older adults in the NHANES I epidemiologic follow–up study. Am J Public Health 1992, 82(3):401-406.
- [21]Steinbach U: Social networks, institutionalization, and mortality among elderly people in the United States. J GerontoL 1992, 47:S 183-S 190.
- [22]Wolinsky FD, Johnson RL, Stump TE: The risk of mortality among older adults over an eight–year period. Gerontologist. 1995, 35:150-161.
- [23]Simons LA, McCallum J, Simons J: Impact of loneliness and living alone. JAMA Intern Med 2013, 173(4):322-3.
- [24]Jagger C, Clarke M: Mortality risks in the elderly: five–year follow–up of a total population. Int J Epidemiol 1988, 17(1):111-4.
- [25]Murata C, Takaaki K, Hori Y, Miyao D, Tamakoshi K, Yatsuya H, et al. Effects of social relationships on mortality among the elderly in a Japanese rural area: an 88–month follow–up study. J Epidemiol. 2005;15(3):78–84.
- [26]Rozzini R, Trabucchi M: Health status in elderly persons living alone. JAMA Intern Med 2013, 173(4):323-4.
- [27]Holt–Lunstad J, Smith TB, Baker M, Harris T, Stephenson D: Loneliness and social isolation as risk factors for mortality: a meta–analytic review. Perspect Psychol Sci 2015, 10(2):227-37.
- [28]Hanson BS, Isacsson SO, Janzon L, Lindell SE: Social network and social support influence mortality in elderly men. Am J Epidemio 1989, 130:100-111.
- [29]Kandler U, Meisinger C, Baumert J, Lowel H: Living alone is a risk factor for mortality in men but not women from the general population: a prospective cohort study. BMC Public Health 2007, 7:335. BioMed Central Full Text
- [30]Staehelin K, Schindler C, Spoerri A, Zemp Stutz E. Marital status, living arrangement and mortality: does the association vary by gender? J Epidemiol Community Health. 2011;66(7):e22.
- [31]Covinsky KE: The differential diagnosis of living alone: comment on “Living alone and risk of mortality in older, community–dwelling adults”. JAMA Intern Med 2013, 173(4):321.
- [32]Umberson D: Gender, marital status and the social control of health behavior. Soc Sci Med 1992, 34:907-917.
- [33]Miller–Tutzauer C, Leonard KE, Windle M: Marriage and alcohol use: A longitudinal studyof maturing out. J Stud Alcohol 1991, 52:434-440.
- [34]Grundy EM, Tomassini C: Marital history, health and mortality among older men and women in England and Wales. BMC Public Health 2010, 10:554. BioMed Central Full Text
- [35]Manzoli L, Villari P, M Pirone G, Boccia A: Marital status and mortality in the elderly: a systematic review and meta–analysis. Soc Sci Med 2007, 64(1):77-94.
- [36]Niti M, Yap KB, Kua EH, Tan CH, Ng TP: Physical, social and productive leisure activities, cognitive decline and interaction with APOE–epsilon4 genotype in Chinese older adults. Int Psychogeriatr 2008, 20(2):237-51.
- [37]Department of Statistics, Ministry of Trade and Industry, Republic of Singapore. Census of Population 2010 Statistical Release 2: Households and Housing.. http://www.singstat.gov.sg/publications/publications–and–papers/cop2010/census10_stat_release2#sthash.rEF1KOMS.dpuf webcite
- [38]National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Final report. Circulation. 2002;106:3143–3421.
- [39]Sheikh JI, Yesavage JA: Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. In Clinical gerontology: a guide to assessment and intervention. Edited by Brink TL. the Haworth Press, New York, NY; 1986:165-73.
- [40]Nyunt MSZ, Jin AZ, Fones CSL, Ng TP: Criterion–based validity and reliability of the Geriatric Depression Screening Scale (GDS–15) in a large validation sample of community–living Asian older adults. Aging Ment Health 2009, 13(3):376-382.
- [41]Collin C, Wade DT, Davies S, Horne V: The Barthel ADL Index: a reliability study. Int Disabil Stud 1988, 10(2):61-63.
- [42]Mp L, Brody EM: Assessment of older people: self–maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179-86.
- [43]Ng TP, Niti M, Chiam PC, Kua EH: Physical and cognitive domains of the instrumental activities of daily living: validation in a multiethnic population of Asian older adults. J Gerontol Biol Med Sci 2006, 61:726-35.
- [44]Niti M, Ng TP, Chiam PC, Kua EH: Item response bias was present in Instrumental Activity of Daily Living Scale in Asian older adults. J Clin Epidemiol 2007, 60:366-74.
- [45]Haslbeck JW, McCorkle R, Schaffer D: Chronic illness Self–Management While Living Alone in Later Life: A Systematic Integrative Review. Res Aging 2012, 34(5):507-47.
- [46]Huang LH, Lin YC: The health status and needs of community elderly living alone. J Nurs Res 2002, 10(3):227-36.
- [47]Prohaska TR, Glasser M: Patients’ views of family involvement in medical care decisions and encounters. Res Aging 1996, 18:52-69.
- [48]Stone R, Cafferata GL, Sangl J: Caregivers of the frail elderly: A national profile. Gerontologist 1987, 27:616-26.
- [49]Burnette D: Managing chronic illness alone in late life: Sisyphus at work. In Qualitative studies in social work research. Edited by Riessman CK. SAGE, Thousand Oaks, CA; 1993:5-27.
- [50]Bucholz EM, Krumholz HM: Loneliness and Living Alone: What Are We Really Measuring? Arch Intern Med 2012, 172(14):1084-1085.