Cardiac structure and function in relation to cardiovascular risk factors in Chinese

BMC Cardiovascular Disorders

Ji-Guang Wang¹  Qi-Fang Huang¹  Chang-Sheng Sheng¹  Ming Liu¹  Yan Li¹  Yi Zhang¹ 

[1] Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Ruijin 2nd Road, Shanghai 200025, China

关键词: Blood pressure;    Left ventricular diastolic dysfunction;    Left ventricular hypertrophy;    Left atrial enlargement;   

Others  :  1084616
DOI  :  10.1186/1471-2261-12-86

 received in 2012-02-02, accepted in 2012-09-28,  发布年份 2012

【 摘 要 】

Background

Cardiac structure and function are well-studied in Western countries. However, epidemiological data is still scarce in China.

Methods

Our study was conducted in the framework of cardiovascular health examinations for the current and retired employees of a factory and their family members. According to the American Society of Echocardiography recommendations, we performed echocardiography to evaluate cardiac structure and function, including left atrial volume, left ventricular hypertrophy and diastolic dysfunction.

Results

The 843 participants (43.0 years) included 288 (34.2%) women, and 191 (22.7%) hypertensive patients, of whom 82 (42.9%) took antihypertensive drugs. The prevalence of left atrial enlargement, left ventricular hypertrophy and concentric remodeling was 2.4%, 5.0% and 12.7%, respectively. The prevalence of mild and moderate-to-severe left ventricular diastolic dysfunction was 14.2% and 3.3%, respectively. The prevalence of these cardiac abnormalities significantly (P ≤ 0.002) increased with age, except for the moderate-to-severe left ventricular diastolic dysfunction. After adjustment for age, gender, body height and body weight, left atrial enlargement was associated with plasma glucose (P = 0.009), and left ventricular hypertrophy and diastolic dysfunction were significantly associated with systolic and diastolic blood pressure (P ≤ 0.03), respectively.

Conclusions

The prevalence of cardiac structural and functional abnormalities increased with age in this Chinese population. Current drinking and plasma glucose had an impact on left atrial enlargement, whereas systolic and diastolic blood pressures were major correlates for left ventricular hypertrophy and diastolic dysfunction, respectively.

【 授权许可】

   
2012 Zhang et al.; licensee BioMed Central Ltd.

【 图 表 】

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