Most functional outcomes are similar for men and women after hip fracture: a secondary analysis of the enhancing mobility after hip fracture trial

BMC Geriatrics

Catherine Sherrington⁴  Ian D Cameron²  Stephen R Lord³  Anne M Moseley⁴  Lindy Clemson¹  Lynda M Woodward¹ 

[1] Australian Research Council Centre for Excellence in Population Ageing Research, Sydney, Australia;John Walsh Centre for Rehabilitation Research, Sydney Medical School, The University of Sydney, Sydney, Australia;Neuroscience Research Australia, The University of New South Wales, Sydney, Australia;Musculoskeletal Division, The George Institute for Global Health, Sydney Medical School, The University of Sydney, Sydney, Australia

关键词: Rehabilitation;    Exercise;    Hip fracture;    Gender;   

Others  :  1089783
DOI  :  10.1186/1471-2318-14-140

 received in 2014-08-14, accepted in 2014-12-11,  发布年份 2014

【 摘 要 】

Background

The impact of gender on functional outcomes after hip fracture is not known. We aimed to determine the extent to which gender influenced functional outcome and response to exercise in older people after hip fracture, and to determine if any differences persisted after adjusting for cognition, weight and age.

Method

Secondary analysis of data from the Enhancing Mobility After Hip Fracture trial in which older people after hip fracture received either a lower or higher intensity exercise program. Functional outcomes included physical performance and self-reported measures. Regression models were used to compare genders at baseline, week 4 and week 16, with adjustment for baseline values, cognition, weight and age. Interaction terms were used to assess a differential impact of the intervention by gender.

Results

Outcome data were available for 160 participants, 30 men (19%) and 130 women (81%) at baseline, with the withdrawal of 4 men (13%) and 6 women (5%) at week 16. There were no gender differences for any baseline measures or for most of the 19 functional outcome measures at weeks 4 and 16. At week 4 men performed better in knee extensor strength (2.1kg, 95% CI 0.6 to 3.7, p < 0.01). This difference did not persist after adjustment for body weight, however persisted after adjusting for baseline, cognition, and age (p = 0.038). At week 4, men performed better in coordinated stability (-10.0 error score, 95% CI -17.6 to -2.4, p=0.010) and this persisted after adjusting for baseline values only but not for cognition and age (p = 0.073). At week 16, men performed better in coordinated stability (-10.2 error score, 95% CI -18.4 to -1.9, p=0.016) and this persisted after adjusting only for cognitive impairment (p = 0.029) but not for age and baseline (p = 0.135). There was no indication of a differential impact of intervention type on the basis of gender.

Conclusions

A few between gender differences were observed in strength and balance, however these appeared to be confounded by body weight, age and/or cognition.

【 授权许可】

   
2014 Woodward et al.; licensee BioMed Central.

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