Diabetes IN develOpment (DINO): the bio-psychosocial, family functioning and parental well-being of youth with type 1 diabetes: a longitudinal cohort study design

BMC Pediatrics

Frank J. Snoek⁷  Per Winterdijk⁸  Jaap Oosterlaan¹  Roos Nuboer³  Marjolein Luman¹  Euphemia C. A. M. Houdijk⁵  Willie M. Bakker-van Waarde²  Henk Jan Aanstoot⁸  Joost Rotteveel⁶  Maartje de Wit⁴  Minke M. A. Eilander⁴ 

[1] Department Clinical Neuropsychology, Vrije Universiteit, Van der Boechorststraat 1, Amsterdam, 1081, BT, The Netherlands;Department Pediatrics, University Hospital of Groningen, Hanzeplein 1, Groningen, 9700, RB, The Netherlands;Department of Pediatrics, Meander Medical Centre, Maatweg 3, Amersfoort, 3813, TZ, The Netherlands;EMGO+Institute for Health and Care Research, VU University Medical Center, Van der Boechorststraat 7, Amsterdam, 1081, BT, The Netherlands;Department of Pediatrics, Haga Hospital Juliana Children’s Hospital, Sportlaan 600, the Hague, 2566, MJ, The Netherlands;Department of Pediatrics, VU Medical Center, De Boelelaan 1118, Amsterdam, 1081, HV, The Netherlands;Department of Medical Psychology, Academic Medical Center (AMC), Meibergdreef 9, Amsterdam, 1100, DD, The Netherlands;Diabeter, Center for Pediatric and Adolescent Diabetes Care and Research, Blaak 6, Rotterdam, 3011, TA, The Netherlands

关键词: Parents;    Psychosocial;    HbA1c;    Cognition;    Adolescence;    Well-being;    Quality of life;    Youth;    Development;    Type 1 diabetes;   

Others  :  1219308
DOI  :  10.1186/s12887-015-0400-1

 received in 2014-12-08, accepted in 2015-07-02,  发布年份 2015

【 摘 要 】

Background

Strict glycemic control during adolescence decreases the risk of developing complications later in life, even if this level of control is not maintained afterwards. However, the majority of adolescents with type 1 diabetes (T1D) are in poor control and so far medical or psychological interventions have shown limited success. Adolescence is characterized by major biological, psychosocial, cognitive and parent–child relationship changes and the complex interaction between these developmental trajectories, and its impact on health outcomes is still poorly understood. A specific topic of interest in this context is the timing of diagnosis. The longitudinal study DINO (Diabetes IN develOpment) aims to examine:

1) If and how the onset of T1D before vs. during puberty results in different outcomes of glycemic control, self-management, psychological functioning and diabetes-related quality of life.

2) The timing of onset of disturbed eating behavior, its risk factors and its prospective course in relation to glycemic and psychological consequences.

3) If and how the onset of T1D before vs. during puberty results in different family functioning and parental well-being.

4) If and how the cognitive development of youth with T1D relates to glycemic control and diabetes self-management.

Methods/design

DINO, a longitudinal multi-center cohort study is conducted in youth with T1D in the age range 8–15 years at baseline. Participants will be divided into two subgroups: pre-pubertal and pubertal. Both groups will be followed for 3 years with assessments based on a bio-psychosocial model of diabetes, scheduled at baseline, 12 months, 24 months and 36 months examining the biological, psychosocial -including disturbed eating behaviors- and cognitive development, family functioning and parental well-being.

Discussion

A better understanding of how the different trajectories affect one another will help to gain insight in the protective and risk factors for glycemic outcomes and in who needs which support at what moment in time. First results are expected in 2016.

【 授权许可】

   
2015 Eilander et al.

【 图 表 】

Fig. 1.

Fig. 2.

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