期刊论文详细信息
BMC Research Notes
A note on statistical and biological communication: a case study of the 2009 H1N1 pandemic
Hanna K Jankowski2  Jane M Heffernan1  Jeremy Recoskie2 
[1] Centre for Disease Modelling, York Institute for Health Research, York University, Toronto, ON, Canada;Department of Mathematics and Statistics, York University, Toronto, ON, Canada
关键词: Influenza;    H1N1;    Reproducibility;    Miscommunication;    Statistical misinterpretation;   
Others  :  1091260
DOI  :  10.1186/1756-0500-7-939
 received in 2012-10-23, accepted in 2014-11-06,  发布年份 2014
PDF
【 摘 要 】

Background

Many academic fields contribute to medical and health research. As a result, due to the various backgrounds of these disciplines, inference and interpretation of study findings can be misconstrued.

Results

In a recent survey of the 2009 H1N1 literature we found many instances where semantic and statistical misinterpretation or miscommunication could potentially arise. We provide examples where miscommunication or misinterpretation of study results can mislead the interdisciplinary reader. We also provide some additional background on statistical methodology and theory for the interested reader.

Discussion

This work presented some examples where statistical misinterpretation or miscommunication could arise in the H1N1 literature. However, similar challenges are encountered in other subjects and disciplines. To reduce the probability of this occurring it is necessary that (1) readers consider papers with a critical eye and approach citations with caution; (2) authors take more care to present study methods with more clarity. Reproducibility of the study results would greatly aid readers in their ability to understand and interpret the given findings.

【 授权许可】

   
2014 Recoskie et al.; licensee BioMed Central.

【 预 览 】
附件列表
Files Size Format View
20150128170623352.pdf 247KB PDF download
Figure 3. 22KB Image download
Figure 2. 24KB Image download
Figure 1. 26KB Image download
【 图 表 】

Figure 1.

Figure 2.

Figure 3.

【 参考文献 】
  • [1]Monsalvo AC, Batalle JP, Lopez MF, Krause JC, Klemenc J, Hernandez JZ, Maskin B, Bugna J, Rubinstein C, Aguilar L, Dalurzo L, Libster R, Savy V, Baumeister E, Aguilar L, Cabral G, Font J, Solari L, Weller KP, Johnson J, Echavarria M, Edwards KM, Chappell JD, Crowe Jr JE, Williams JV, Melendi GA, Polack FP: Severe pandemic 2009 H1N1 influence disease due to pathogenic immune complexes. Nat Med 2011, 17:195-199.
  • [2]Hancock K, Veguilla V, Lu X, Zhong W, Butler EN, Sun H, Liu F, Dong L, DeVos JR, Gargiullo PM, Brammer TL, Cox NJ, Tumpey TM, Katz JM: Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N Engl J Med 2009, 361:1945-1952.
  • [3]Centers for DiseaseControlandPrevention: Serum cross-reactive antibody response to a novel influenza A (H1N1) virus after vaccination with seasonal influenza vaccine. MMWR Morb Mortal Wkly Rep 2009, 58:521-524.
  • [4]Holt P, Jones C: The development of the immune system during pregnancy and early life. Allergy 2000, 55:688-697.
  • [5]Tuite AR, Greer AL, Whelan M, Winter AL, Lee B, Yan P, Wu J, Moghadas S, Buckeridge D, Pourbohloul B, Fisman DN: Estimated epidemiologic parameters and morbidity associated with pandemic H1N1 influenza. CMAJ 2010, 182(2):131-136.
  • [6]Chowell G, Bertozzi SM, Colchero MA, Lopez-Gatell H, Alpuche-Aranda C, Hernandez M, Miller MA: Severe respiratory disease concurrent with the circulation of H1N1 influenza. N Engl J Med 2009, 361:674-679.
  • [7]Editorial N: Devil in the details. Nature 2011, 470:305-306.
  • [8]Ince D: The problem of reproducibility. Chance 2012, 25(3):4-7.
  • [9]Strasak A, Zaman Q, Pfeiffer K, Gobel G, Ulmer H: Statistical errors in medical research – a review of common pitfalls. Swiss Med Wkly 2007, 137:44-49.
  文献评价指标  
  下载次数:37次 浏览次数:19次