BMC Research Notes | |
Cutaneous metastasis of prostate carcinoma treated with radiotherapy: a case presentation | |
Paul De Souza2  Najmun Nahar1  Melvin Chin3  Gabriel Mak3  | |
[1] Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, Australia;Ingham Institute, School of Medicine, University of Western Sydney, Liverpool Hospital, Sydney, Australia;Prince of Wales Hospital; Prince of Wales Clinical School, University of New South Wales, Sydney, Australia | |
关键词: Radiotherapy; Cutaneous metastasis; Metastasis; Prostate cancer; | |
Others : 1136439 DOI : 10.1186/1756-0500-7-505 |
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received in 2014-01-03, accepted in 2014-08-01, 发布年份 2014 | |
【 摘 要 】
Background
Prostate cancer is a commonly diagnosed and treated malignancy, although it rarely presents with cutaneous metastases. In this case presentation, we describe the diagnosis and treatment with radiotherapy of a patient who presented with cutaneous metastases on his chest wall secondary to prostate cancer.
Case presentation
In 2006, a 73-year-old Caucasian gentleman with metastatic castration resistant prostate cancer treated with mitoxantrone and prednisolone presented with cutaneous nodules on his chest wall. A punch biopsy diagnosed cutaneous metastases, with histological confirmation with positive staining for cytokeratin, PSA (prostate specific antigen) and PAP (prostatic acid phosphatise). Systemic treatment was ceased due to progressive disease; radiotherapy was used to treat these nodules with a durable clinical response. The patient died five months after initial diagnosis of cutaneous metastases.
Conclusions
In this report, a rare metastatic manifestation of a common malignancy is presented. Whilst dermal metastases carries a poor prognosis from reported literature, this is the first report of radiotherapy providing a durable clinical response with relief from bleeding and pain.
【 授权许可】
2014 Mak et al.; licensee BioMed Central Ltd.
【 预 览 】
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20150313021435741.pdf | 1436KB | download | |
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Figure 1. | 153KB | Image | download |
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