Antenatal iron and folic acid supplementation use by pregnant women in Khartoum, Sudan

BMC Research Notes

Ishag Adam²  Abdulmutalab M Imam²  Ahmed Saeed²  Gasim I Gasim¹  Hala Abdullahi² 

[1] Medical College, Qassim University, Gassim, Saudi Arabia;Department of Obstetrics and Gynecology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan

关键词: Sudan;    Pregnant women;    Iron;    Folic acid;   

Others  :  1131714
DOI  :  10.1186/1756-0500-7-498

 received in 2013-09-19, accepted in 2014-07-31,  发布年份 2014

【 摘 要 】

Background

Anaemia during pregnancy can lead to adverse maternal and perinatal outcomes. The WHO recommends that all pregnant women in areas where anaemia is prevalent receive supplements of iron and folic acid. However, due to many factors, the use of iron and folic acid supplementation is still low in many countries. This study was conducted to assess the rates of iron-folic supplementation and the associated factors during pregnancy and the effects of taking iron-folic acid supplementation on rates of maternal anaemia and low birth weight (LBW) infants.

Methods

A cross-sectional study was conducted at Khartoum Hospital, Sudan. Enrolled women answered a questionnaire on socio-demographics characteristics, their pregnancy and delivery.

Results

Of 856 women, 788 (92.1%) used iron-folic acid supplementation during pregnancy and 65.4% used folic acid. While place of residence, occupation and level of education were not associated with iron-folic acid usage, older age (OR = 3, CI = 1.4–6.3) and use of antenatal care (OR = 14.3, CI = 7.4–27.5) were associated with iron-folic acid use. Primiparity (OR = 3.8, CI = 1.9–7.6), maternal employment (OR = 3.9, CI = 2.25–6.77) and use of antenatal care (OR = 7.9, CI = 4.1–15) were the factors associated with folic acid. Using iron-folic acid was protective against anaemia (OR = 0.39, CI = 0.2–0.7) and LBW infants (OR = 0.3, CI = 0.17–0.68).

Conclusion

There was a high rate of iron-folic acid supplementation use among pregnant women in Khartoum, Sudan, which was beneficial in preventing anaemia in expectant mothers and infants of LBW.

【 授权许可】

   
2014 Abdullahi et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]World Health Organization: Global health risks: mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization; 2009. http://www.who.int/healthinfo/global_burden_disease/global_health_risks/en/index.html webcite
• [2]De Benoist B, McLean E, Egli I, Cogswell M: Worldwide Prevalence of anaemia 1993–2005: WHO Global Database on Anaemia. Geneva: World Health Organization; 2008.
• [3]Ali AA, Rayis DA, Abdallah TM, Elbashir MI, Adam I: Severe anaemia is associated with a higher risk for preeclampsia and poor perinatal outcomes in Kassala hospital, eastern Sudan. BMC Res Notes 2011, 4:311.
• [4]Ayoya MA, Bendech MA, Zagré NM, Tchibindat F: Maternal anaemia in West and Central Africa: time for urgent action. Public Health Nutr 2012, 15:916-927.
• [5]World Health Organization, Department of Making Pregnancy Safer and Department of Reproductive Health and Research: Standards for maternal and neonatal care Group 1: General standards of care for healthy pregnancy and childbirth. World Health Organization; http://www.who.int/reproductivehealth/publications/maternal_perinatal_health/a91272/en/ webcite
• [6]Kidanto HL, Mogren I, Lindmark G, Massawe S, Nystrom L: Risks for preterm delivery and low birth weight are independently increased by severity of maternal anaemia. S Afr Med J 2009, 99:98-102.
• [7]Rohilla M, Raveendran A, Dhaliwal LK, Chopra S: Severe anaemia in pregnancy: a tertiary hospital experience from northern India. J Obstet Gynaecol 2010, 30:694-696.
• [8]Adam I, Elhassan EM, Haggaz AE, Ali AA, Adam GK: A perspective of the epidemiology of malaria and anaemia and their impact on maternal and perinatal outcomes in Sudan. J Infect Dev Ctries 2011, 5:83-87.
• [9]Maina-Gathigi L, Omolo J, Wanzala P, Lindan C, Makokha A: Utilization of Folic Acid and iron supplementation services by pregnant women attending an antenatal clinic at a regional referral hospital in Kenya. Matern Child Health J 2013, 17:1236-1242.
• [10]Ogundipe O, Hoyo C, Østbye T, Oneko O, Manongi R, Lie RT, Daltveit AK: Factors associated with antenatal folic acid and iron supplementation among 21,889 pregnant women in Northern Tanzania: a cross-sectional hospital-based study. BMC Public Health 2012, 12:481.
• [11]Leung BM, Kaplan BJ: Perinatal depression: prevalence, risks, and the nutrition link–a review of the literature. J Am Diet Assoc 2009, 109:1566-1575.
• [12]Nilsen RM, Vollset SE, Gjessing HK, Magnus P, Meltzer HM, Haugen M, Ueland PM: Patterns and predictors of folic acid supplement use among pregnant women: the Norwegian Mother and Child Cohort Study. Am J Clin Nutr 2006, 84:1134-1141.
• [13]Timmermans S, Jaddoe VW, Mackenbach JP, Hofman A, Steegers-Theunissen RP, Steegers EA: Determinants of folic acid use in early pregnancy in a multi-ethnic urban population in The Netherlands: the Generation R study. Prev Med 2008, 47:427-432.
• [14]Knudsen VK, Hansen HS, Ovesen L, Mikkelsen TB, Olsen SF: Iron supplement use among Danish pregnant women. Public Health Nutr 2007, 10:1104-1110.
• [15]Lutsey PL, Dawe D, Villate E, Valencia S, Lopez O: Iron supplementation compliance among pregnant women in Bicol, Philippines. Public Health Nutr 2008, 11:76-82.
• [16]Seck BC, Jackson RT: Determinants of compliance with iron supplementation among pregnant women in Senegal. Public Health Nutr 2008, 11:596-605.
• [17]Adam I, Khamis AH, Elbashir MI: Prevalence and risk factors for anaemia in pregnant women of eastern Sudan. Trans R Soc Trop Med Hyg 2005, 99:739-743.
• [18]Bukar M, Audu BM, Yahaya UR, Melah GS: Anaemia in pregnancy at booking in Gombe, North-eastern Nigeria. J Obstet Gynaecol 2008, 28:775-778.
• [19]Stoltzfus RJ: Iron interventions for women and children in low-income countries. J Nutr 2011, 141:756-762.
• [20]Palma S, Perez-Iglesias R, Prieto D, Pardo R, Llorca J, Delgado-Rodriguez M: Iron but not folic acid supplementation reduces the risk of low birth weight in pregnant women without anaemia: a case–control study. J Epidemiol Community Health 2008, 62:120-124.
• [21]Liu JM, Mei Z, Ye R, Serdula MK, Ren A, Cogswell ME: Micronutrient Supplementation and Pregnancy Outcomes: Double-Blind Randomized Controlled Trial in China. JAMA Intern Med 2013, 7:1-7.