Left atrial metastasis of renal cell carcinoma: a case report and review of the literature

BMC Research Notes

Hideki Sakai¹  Yasushi Mochizuki¹  Tomohiro Matsuo¹  Kensuke Mitsunari¹  Yasuyoshi Miyata¹  Kojiro Ohba¹ 

[1] Department of Nephro-Urology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

关键词: Renal cell carcinoma;    Metastasis;    Atrium;   

Others  :  1130552
DOI  :  10.1186/1756-0500-7-520

 received in 2013-10-21, accepted in 2014-08-06,  发布年份 2014

【 摘 要 】

Background

Cardiac metastasis of renal cell carcinoma is an exceptional event, particularly when there is lack of inferior vena cava involvement. Indeed, only a few cases have been reported worldwide thus far. Moreover, discussion of treatment and follow-up strategies for cardiac metastasis of renal cell carcinoma is important because of the high risk of sudden death.

Case presentation

We report the case of a 75-year-old Japanese man with metastatic tumor in the left atrium from renal cell carcinoma. He had a history of right renal cell carcinoma, for which he had undergone hand-assisted laparoscopic nephrectomy. Lung and bone metastases were detected after nephrectomy, and treatment with interferon-alpha was initiated. After disease progression, he was treated concurrently with targeted molecular therapy and radiotherapy for bone metastasis. After these therapies, a 42 × 24 mm mass was found on transthoracic echocardiography in left atrium without involvement of the right atrium or inferior vena cava. The provisional diagnosis was metastatic mass or myxoma, and surgical resection was performed. Histopathological examination led to a final diagnosis of metastatic tumor from clear cell renal cell carcinoma.

Conclusion

Cardiac metastasis, metastasis to the left atrium in particular, is rare in patients with renal cell carcinoma. In our study, surgery of the cardiac mass was effective to avoid sudden death and quality of life decline resulting from heart failure. We describe this case and review cardiac metastasis of renal cell carcinoma.

【 授权许可】

   
2014 Ohba et al.; licensee BioMed Central Ltd.

【 图 表 】

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