Geographic variations and temporal trends in prostate cancer in Martinique over a 25-year period

BMC Research Notes

Clarisse Joachim²  Patrick Escarmant¹  Annie Sasco³  Jacqueline Veronique-Baudin²  Stephane Michel⁵  Jonathan Macni⁴  Rishika Banydeen⁴  Moustapha Dieye² 

[1] Pôle de Cancérologie Hématologie Urologie, Centre Hospitalier Universitaire de la Martinique, Fort-de-France BP 632, 97261, Martinique;Pôle de Cancérologie Hématologie Urologie, Registre des Cancers de la Martinique – UF 1441 Recherche & Registre, Centre Hospitalier Universitaire de la Martinique, 127 Route de Redoute, Fort-de-France 97200, Martinique;INSERM, ISPED, Centre INSERM U897- Epidémiologie-Biostatistique, Bordeaux F-33000, France;Registre des Cancers de la Martinique, AMREC, 127 Route de Redoute, Fort-de-France, Martinique;AMREC, 127 Route de Redoute, Fort-de-France, Martinique

关键词: Environmental exposure;    Spatial distribution;    Period analysis;    Age-period-cohort model;    Incidence rate;    Prostate cancer;   

Others  :  1133242
DOI  :  10.1186/1756-0500-7-262

 received in 2012-12-17, accepted in 2014-04-03,  发布年份 2014

【 摘 要 】

Background

In Martinique, prostate cancer incidence rates have been increasing since the 1980s and are actually among the highest worldwide. Exposure to lifestyle (changes in dietary habits), environmental factors (exposure to organochlorine pesticides) and modifications in diagnostic and screening procedures, are favored etiological hypotheses. The aim of the present study is to describe and interpret prostate cancer incidence trends over the past 25 years (1981–2005) in Martinique.

Methods

Data on incident prostate cancer cases from 1981 to 2005 were obtained from the population-based Martinique Cancer Registry. World age-standardised incidence rates were calculated and an age-period-cohort model was used to determine average annual variations for prostate cancer during the study period. Age and period effects were assessed, employing the method proposed by Clayton and Schifflers. Relative changes in prostate cancer incidence, at five-year intervals between 1981 and 2005, were also studied with an organochlorine pesticide exposure index, built as a proxy of the relative intensity of chlordecone use on the island between 1973 and 1993.

Results

Prostate cancer incidence was found to increase by 5.07% annually between 1981 and 2005. Compared to 1981–1985, prostate cancer relative risk, in men aged 50–74 years and 75 years and above was respectively 5.98% and 3.07% from 2001 to 2005. An inverse association between population pesticide exposure levels and prostate cancer risk was also highlighted, with highest prostate cancer incidences observed in urban zones showing the lowest soil contamination levels by the chlordecone pesticide (zone 1).

Conclusion

No conclusive association was found between the intensity of pesticide use and the subsequent rise in prostate cancer incidence. However, it remains necessary to develop and reinforce continuous monitoring of prostate cancer incidence and mortality trends on the island. Further studies are also needed in order to consider other risk factors such as modifications in diagnostic and screening procedures over the last 25 years.

【 授权许可】

   
2014 Dieye et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Parkin DM, Bray F, Ferlay J, Pisani P: Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001, 94(2):153-156.
• [2]Curado MP, Edwards B, Shin HR, Storm H, Ferlay J, Heanue M, Boyle P (Eds): Cancer Incidence in Five Continents, Vol. IX. 160th edition. Lyon, IARC: IARC Scientific Publications; 2007. http://www-dep.iarc.fr/CI5-IX/PDF/BYSITE/S_C61.pdf webcite
• [3]Baldi I, Mohammed-Brahim B, Brochard P, Dartigues JF, Salamon R: Delayed health effects of pesticides: review of current epidemiological knowledge. R Rev Epidemiol Sante Publique 1998, 46(2):134-142.
• [4]Dubuisson C, Héraud F, Leblanc JC, Gallotti S, Flamand C, Blateau A, Quenel P, Volatier JL: Impact of subsistence production on the management options to reduce the food exposure of the Martinican population to Chlordecone. Regul Toxicol Pharmacol 2007, 49(1):5-16.
• [5]Bocquené G, Franco A: Pesticide contamination of the coastline of Martinique. Mar Pollut Bull 2005, 51(5–7):612-619.
• [6]Hammond B, Katzenellenbogen BS, Krauthammer N, McConnell J: Estrogenic activity of the insecticide chlordecone (Kepone) and interaction with uterine estrogen receptors. Proc Natl Acad Sci 1979, 76:6641-6659.
• [7]Coat S, FRA Ecole Nationale de la Santé Publique: Caractérisation de l'exposition de la population Martiniquaise aux pesticides organochlorés par la consommation de ressources aquatiques. Mémoire ENSP d'Ingénieur Sanitaire: FRA Ecole Nationale de la Santé Publique; 2002:49.
• [8]Blateau A, Heraud F, Bordet , Merle S, Reilhes O, Quénel P: Enquête Reso: enquête sur les résidus organochlorés dans les aliments. Guadeloupe, Martinique; 2007. Octobre 2005-Janvier
• [9]Cabidoche YM, Achard R, Cattan P, Clermont-Dauphin C, Massat F, Sansoulet J: Long-term pollution by chlordecone of tropical volcanic soils in the French West Indies: A simple leaching model accounts for current residue. Environ Pollut 2009, 157:1697-1705.
• [10]Parkin DM, Chen VW, Ferlay J, Galceran J, Storm HH, Whelan S (Eds): Comparability and quality control in cancer registration; IARC technical report N° 19. Lyon, France: International Agency for Research on Cancer; 1994.
• [11]Schouten LJ, Straatman H, Kiemeney LA, Gimbrère CH, Verbeek AL: The capture-recapture method for estimation of cancer registry completeness: a useful tool? Int J Epidemiol 1994, 23(6):1111-1116.
• [12]Desprats JF, Comte JP, Perian EG: Cartographie par analyse multicritère des sols potentiellement pollués par organochlorés en Martinique - Phase 2. BGM RP-52257-FR: Rapport; 2003.
• [13]Clayton D, Schifflers E: Models for temporal variation in cancer rates. I: Age-period and age-cohort models. Stat Med 1987, 6(4):449-467.
• [14]Clayton D, Schifflers E: Models for temporal variation in cancer rates. II: Age-period-cohort models. Stat Med 1987, 6(4):469-481.
• [15]Belot A, Grosclaude P, Bossard N, Jougla E, Benhamou E, Delafosse P, Guizard AV, Molinié F, Danzon A, Bara S, Bouvier AM, Trétarre B, Binder-Foucard F, Colonna M, Daubisse L, Hédelin G, Launoy G, Le Stang N, Maynadié M, Monnereau A, Troussard X, Faivre J, Collignon A, Janoray I, Arveux P, Buemi A, Raverdy N, Schvartz C, Bovet M, Chérié-Challine L, et al.: Cancer incidence and mortality in France over the period 1980–2005. Rev Epidemiol Sante Publique 2008, 56(3):159-175.
• [16]Quinn M, Babb P: Patterns and trends in prostate cancer incidence, survival, prevalence and mortality. Part I: international comparisons. BJU Int 2002, 90:162-173.
• [17]Hsing AW, Devesa SS: Trends and patterns of prostate cancer: what do they suggest? Epidemiol Rev 2001, 23(1):3-13.
• [18]Vercelli M, Quaglia A, Marani E, Parodi S: Prostate cancer incidence and mortality trends among elderly and adult Europeans. Crit Rev Oncol Hematol 2000, 35(2):133-144.
• [19]Alavanja MC, Samanic C, Dosemeci M, Lubin J, Tarone R, Lynch CF, Knott C, Thomas K, Hoppin JA, Barker J, Coble J, Sandler DP, Blair A: Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort. Am J Epidemiol 2003, 157(9):800-814.
• [20]Coldman AJ, Phillips N, Pickles TA: Trends in prostate cancer incidence and mortality: an analysis of mortality change by screening intensity. CMAJ 2003, 168(1):31-35.
• [21]Agence Française de Sécurité Sanitaire des Aliments: Actualisation de l'exposition alimentaire au chlordécone de la population antillaise évaluation de l'impact de mesures de maîtrises des risques. Paris: La Documentation française; 2007.
• [22]Dieye M, Veronique-Baudin J, Draganescu C, Azaloux H: Cancer incidence in Martinique: a model of epidemiological transition. Eur J Cancer Prev 2007, 16(2):95-101.
• [23]Veronique-Baudin J, Dieye M, Kouyoumdjian JC, Vacheron F, Draganescu C, Azaloux H: Case–control study of the genes of receptors of the androgens of vitamin-D and of 5- alphareductase in a population of Afro-Caribbean population with prostate cancer. Prog Urol 2006, 16(3):303-310.
• [24]Rosenblatt KA, Wicklund KG, Stanford JL: Sexual factors and the risk of prostate cancer. Am J Epidemiol 2001, 153(12):1152-1158.
• [25]Grönberg H: Prostate cancer epidemiology. Lancet 2003, 361(9360):859-864.
• [26]Mallick S, Blanchet P, Multigner L: Prostate cancer incidence in Guadeloupe, French Caribbean Archipelago. Eur Urol 2005, 47:769-772.
• [27]Multigner L, Ndong JR, Giusti A, Romana M, Delacroix-Maillard H, Cordier S, Jégou B, Thome JP, Blanchet P: Chlordecone exposure and risk of prostate cancer. J Clin Oncol 2010, 28(21):3457-3462.