Multiple aseptic splenic abscesses in a 15 year old patient

BMC Gastroenterology

Tobias Tenenbaum³  Horst Schroten³  Rüdiger Adam³  K Wolfgang Neff²  Metin Sertemir²  Klaus-Peter Becker¹  Alexander J Jordan³ 

[1]Institute for Medical Microbiology and Hygiene, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

[2]Institute of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

[3]Paediatric Infectious Diseases, Department of Paediatrics, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany

关键词: Inflammatory bowel disease;    Metronidazole;    Anaerobic bacteria;    Aseptic;    Abscess;   

Others  :  855731
DOI  :  10.1186/1471-230X-14-20

 received in 2013-10-04, accepted in 2014-02-03,  发布年份 2014

【 摘 要 】

Background

Splenic abscesses in children are rare. In recent years aseptic abscesses have been recognized as a new disease entity, especially in adults.

Case presentation

We present a rare case of a 15 year old girl with aseptic abscesses, in whom antibiotic therapy comprising metronidazole and meropenem was partly beneficial in improving the patient’s clinical condition and inflammatory parameters. Eventually corticosteroid therapy led to complete and long lasting resolution of symptoms. Further diagnostic work-up revealed autoimmune thyroiditis, but no signs of inflammatory bowel disease.

Conclusion

Aseptic splenic abscesses should always prompt clinicians to initiate further diagnostics to determine a potential underlying condition and a regular follow-up. Anaerobic bacteria may play a role in the pathogenesis of the disease and besides corticosteroid treatment antibiotics covering anaerobes may be beneficial.

【 授权许可】

   
2014 Jordan et al.; licensee BioMed Central Ltd.

【 图 表 】

【 参考文献 】

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