期刊论文详细信息
BMC Research Notes
Detection of sleep apnea by case-finding and home monitoring with Somnolter®: a pilot study
Jean-Marie Degryse2  Karen Ferson1  Sanne Calaerts1  Mathias Peeters1  Fabienne Cattrysse1 
[1] Department of Public Health and Primary Care, Katholieke Universiteit Leuven (KUL), Leuven, Belgium;Institut de Recherche Santé et Société, Université Catholique de Louvain (UCL), Brussels, Belgium
关键词: AHI;    OSAS;    OSAHS;    Somnolter®;    Sleep apnea;   
Others  :  1129744
DOI  :  10.1186/1756-0500-7-616
 received in 2013-10-25, accepted in 2014-08-18,  发布年份 2014
PDF
【 摘 要 】

Background

Obstructive sleep apnea and hypopnea syndrome (OSAHS) is a disorder that causes clinical symptoms (e.g. snoring, excessive daytime sleepiness and impaired concentration) that may increase the risk of traffic accidents, cardiovascular disease, type 2 diabetes and reduce the quality of life. A recently developed device (Somnolter®) detects apneas and hypopneas in a home setting, allowing to detect OSAHS in a more comfortable environment compared to the gold standard polysomnography. The aim of our study was to investigate whether the Somnolter® is useful in family practice to identify patients with OSAHS.

Methods

Questionnaires were offered to patients in five general practitioner (GP) practices.

Based on the questionnaire and body mass index, patients with an increased risk of OSAHS were contacted to collaborate in the study. In this convenience sample, 18 patients were successfully tested with the Somnolter® measuring SaO2, mandibular movements, body position, heart rate, nasal air flow and thoracic and abdominal breathing movements. The Somnolter® automatically analyses the data and different parameters to detect OSAHS. Afterwards, the data were manually revised by the researchers.

Results

Out of 365 subjects, 31 met the inclusion criteria and 18 were successfully tested at home. Sixteen out of 18 patients had an Apnea Hypopnea Index (AHI) ≥ 5, ten of them had mild OSAHS, 3 were categorized as moderate OSAHS and finally 3 matched the criteria of severe OSAHS.

Conclusion

The proposed case-finding strategy still needs optimization, but is considered helpful in selecting patients at high risk of OSAHS. OSAHS was detected in 14 out of 18 patients tested with the Somnolter®. In the future the Somnolter® might be a feasible alternative to diagnose OSAHS.

【 授权许可】

   
2014 Cattrysse et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150226102508437.pdf 1470KB PDF download
Figure 3. 40KB Image download
Figure 2. 111KB Image download
Figure 1. 94KB Image download
【 图 表 】

Figure 1.

Figure 2.

Figure 3.

【 参考文献 】
  • [1]Gulleminault C, Lehrman AT, Forno L, Dement WC: Sleep apnoea syndrome: states of sleep and autonomic dysfunction. J Neurol Neurosurg Psychiatry 1977, 40(7):718-725.
  • [2]Lam B, Lam DCL, Ip MSM: Obstructive sleep apnoea in Asia. Int J Tuberc Lung Dis 2007, 11(1):2-11.
  • [3]Kapur V, Strohl KP, Redline S, Iber C, O’Connor G, Nieto J: Underdiagnosis of sleep apnea syndrome in U.S. communities. Sleep Breath 2002, 6(2):49-54.
  • [4]Punjabi NM: The epidemiology of adult obstructive sleep apnea. Proc Am Thorac Soc 2008, 5(2):136-143.
  • [5]Young T, Peppard PE, Gottlieb DJ: Epidemiology of obstructive sleep apnea. Am J Respir Crit Care Med 2002, 165(9):1217-1239.
  • [6]Young T, Palta M, Dempsey J, Skatrud J, Weber SB: The occurence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993, 328:1230-1235.
  • [7]Bixler EO, Vgontzas AN, Lin HM, Ten Have T, Rein J, Vela-Bueno A, Kales A: Prevalence of sleep-disordered breathing in women: effects of gender. Am J Respir Crit Care Med 2001, 163:608-613.
  • [8]Hrubos-Strøm H, Randby A, Namtvedt SK, Kristiansen HA, Einvik G, Benth J, Somers VK, Nordhus IH, Russell MB, Dammen T, Omland T, Kvaemer KJ: A Norwegian population-based study on the risk and prevalence of obstructive sleep apnea: the Akershus Sleep Apnea Project (ASAP). J Sleep Res 2011, 20(1 Pt 2):162-170.
  • [9]Fuhrman C, Fleury B, Nguyên X-L, Delmas M-C: Symptoms of sleep apnea syndrome: high prevalence and underdiagnosis in the French population. Sleep Med 2012, 13(7):852-858.
  • [10]Hiestand DM, Britz P, Goldman M, Phillips B: Prevalence of symptoms and risk of sleep apnea in the US population: results from the national sleep foundation sleep in America 2005 poll. Chest 2006, 130(3):780-786.
  • [11]Marcus CL, Brooks LJ, Draper KA, Gozal D, Halbower AC, Jones J, Schechter MS, Sheldon SH, Spruyt K, Ward SD, Lehmann C, Shiffman RN, American Academy of Pediatrics: Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics 2012, 130(3):e714-e755.
  • [12]Flemons WW, Buysse D, Redline S, Strohl K, Wheatley J, Young T, Douglas N, Levy P, McNicholas W, Fleetham J, White D, Schmidt-Nowarra W, Carley D, Romaniuk J: Sleep – related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. Sleep 1999, 22(5):667-689.
  • [13]Tishler PV, Larkin EK, Schluchter MD, Redline S: Incidence of sleep-disordered breathing in an urban adult population: the relative importance of risk factors in the development of sleep-disordered breathing. JAMA 2003, 289(17):2230-2237.
  • [14]Lee W, Nagubadi S, Kryger MH, Mokhlesi B: Epidemiology of obstructive sleep apnea: a population-based perspective. Expert Rev Respir Med 2009, 2(3):349-364.
  • [15]Eastwood PR, Malhotra A, Palmer LJ, Kezirian EJ, Horner RL, Ip MS, Thurnheer R, Antic NA, Hillman DR: Obstructive sleep apnoea: from pathogenesis to treatment: current controversies and future directions. Respirology 2010, 15(4):587-595.
  • [16]Butt M, Dwivedi G, Khair O, Lip GYH: Obstructive sleep apnea and cardiovascular disease. Int J Cardiol 2010, 139(1):7-16.
  • [17]Kendzerska T, Mollayeva T, Gershon AS, Leung RS, Hawker G, Tomlinson G: Untreated obstructive sleep apnea and the risk for serious long-term adverse outcomes: a systematic review. Sleep Med Rev 2013. doi: 10.1016/j.smrv.2013.01.003
  • [18]Loke YK, Brown JWL, Kwok CS, Niruban A, Myint PK: Association of obstructive sleep apnea with risk of serious cardiovascular events: a systematic review and meta-analysis. Circulation 2012, 5(5):720-728.
  • [19]Epstein LJ, Kristo D, Strollo PJ, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein M: Clinical guideline for the evaluation, management and long-term care of obstrutive sleep apnea in adults. J Clin Sleep Med 2009, 5(3):263-276.
  • [20]Cheliout-Heraut F, Senny F, Djouadi F, Ouayoun M, Bour F: Obstructive sleep apnoea syndrome: comparison between polysomnography and portable sleep monitoring based on jaw recordings. Clin Neurophysiol 2011, 41(4):191-198.
  • [21]Senny F, Djouadi F, Ouayoun M, Bour F: Obstructive sleep apnoea syndrome: comparison between polysomnography and portable sleep monitoring based on jaw recordings. Neurophysiol Clin 2011, 41(4):191-198.
  • [22]Senny F, Maury G, Cambron L, Leroux A, Destiné J, Poirrier R: The sleep/wake state scoring from mandible movement signal. Sleep Breath 2012, 16(2):535-542.
  • [23]Chang SJ, Chae KY: Obstructive sleep apnea syndrome in children: epidemiology, pathophysiology, diagnosis and sequelae. Korean J Pediatr 2010, 53(10):863-871.
  • [24]Young T, Peppard P, Palta M, Hla KM, Finn L, Morgan B, Skatrud J: Population-based study of sleep-disordered breathing as a risk factor for hypertension. Arch Intern Med 1997, 157(15):1746-1752.
  • [25]Young T, Blustein J, Finn L, Palta M: Sleep-disordered breathing and motor vehicle accidents in a population-based sample of employed adults. Sleep 1997, 20(8):608-613.
  • [26]Engleman HM, Kingshott RN, Wraith PK, Mackay TW, Deary IANJ, Douglas NJ: Randomized placebo-controlled crossover trial of continuous positive airway pressure for mild sleep apnea / hypopnea syndrome. Am J Respir Crit Care Med 1999, 159(2):461-467.
  • [27]Engleman HM, Martin SE, Deary IJ, Douglas NJ: Effect of CPAP therapy on daytime function in patients with mild sleep apnoea / hypopnoea syndrome. Thorax 1997, 52(2):114-119.
  文献评价指标  
  下载次数:25次 浏览次数:17次