Relationship between maternal obesity and prenatal, metabolic syndrome, obstetrical and perinatal complications of pregnancy in Indiana, 2008–2010

BMC Pregnancy and Childbirth

Stephanie Dickinson¹  Yi Wang¹  Shingairai A. Feresu² 

[1] Department of Statistics, Indiana University, Indiana Statistical Consulting Center, 309 N Park Ave, Bloomington 47405, IN, USA;School of Health Sciences, College of Health Sciences, Walden University, 155 Fifth Ave. South, Suite 100, Minneapolis 55401, MN, USA

关键词: Metabolic syndrorome;    Reproductive risk factors;    Medical and obstetric complications;    Maternal complications;    Obesity in pregnancy;    Obesity trends;    Maternal prepregnancy obesity;   

Others  :  1228693
DOI  :  10.1186/s12884-015-0696-8

 received in 2015-01-16, accepted in 2015-10-06,  发布年份 2015

【 摘 要 】

Background

Obesity is a serious medical condition affecting more than 30 % of Indiana, and 25 % of Unites States pregnant women. Obesity is related to maternal complications, and significantly impacts the health of pregnant women. The objective of this study was to describe the relationship between maternal complications and pre-pregnancy maternal weight.

Methods

Using logistic regression models, we analyzed 2008 to 2010 birth certificate data, for 255,773 live births abstracted from the Indiana Vital Statistics registry. We examined the risk of reproductive factors, obstetrical complications and perinatal (intrapartum) complications for underweight, healthy weight, overweight and obese women for this population.

Results

Women who received prenatal care were more likely to be obese [adjusted odds ratio (AOR) = 1.82 (1.56–2.13)]. While women with parity of zero (0) were less likely to be obese [AOR = 0.89, 95 % CI (0.86–0.91)]. Women giving birth to twins [AOR = 1.25, 95 % CI (1.17– 1.33)], women delivering by Caesarian section [AOR = 2.31, 95 % CI ( 2.26–2.37)], and women who previously had a Caesarian section [AOR = 1.95, 95 % CI (1.88–2.02)] were more likely to be obese. There was evidence of metabolic like complication in this population, due to obesity. Obesity was significantly associated with obstetrical conditions of the metabolic syndrome, including pre-pregnancy diabetes, gestational diabetes, pre-pregnancy hypertension, pregnancy-induced hypertension and eclampsia [AOR = 5.12, 95 % CI (4.47–5.85); AOR = 3.87, 95 % CI (3.68–4.08); AOR = 7.66, 95 % CI (6.77–8.65); AOR = 3.23, 95 % CI (3.07–3.39); and AOR = 1.77, 95 % CI (1.31–2.40), respectively. Maternal obesity modestly increased the risk of induction, epidural, post-delivery bleeding, and prolonged labor [AOR = 1.26, 95 % CI (1.23–1.29); AOR = 1.15, 95 % CI (1.13–1.18); AOR = 1.20, 95 % CI (1.12–1.28); and AOR = 1.44, 95 % CI (1.30–1.61)], respectively. Obese women were less likely to have blood transfusions [AOR = .74, 95 % CI (0.58–96)], vaginal tears [AOR = 0.51, 95 % CI (0.44–0.59)], or infections [AOR = 86, 95 % CI (0.80–0.93)].

Conclusions

Our results suggest that maternal obesity in Indiana, like other populations in the USA, is associated with high risks of maternal complications for pregnant women. Pre-pregnancy obesity prevention efforts should focus on targeting children, adolescent and young women, if the goal to reduce the risk of maternal complications related to obesity, is to be reached.

【 授权许可】

   
2015 Feresu et al.

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