Conjonctival melanoma metastatic to the breast: a case report

BMC Research Notes

Hassan Errihani²  Yassir Sbitti²  Bassma El Khannoussi¹  Hind Mrabti²  Ibrahim Elghissassi²  Saber Boutayeb²  Youssef Bensouda²  Khadija Setti³  Salima Touri³  Jinane kharmoum³  Hafida Benhammane¹  Mesmoudi Mohamed²  Saoussane Kharmoum² 

[1] Departement of Medical Oncology, University Hospital Hassan II, Fes, Morocco;Departement of Medical Oncology, National Institute of Oncology, Poste Madinat al Irfane, Rabat BP 6213, Morocco;Departement of Pathology, Rabat, Morocco

关键词: Metastatic melanoma;    Breast metastases;    Conjunctival melanoma;   

Others  :  1129733
DOI  :  10.1186/1756-0500-7-621

 received in 2013-01-17, accepted in 2014-09-04,  发布年份 2014

【 摘 要 】

Background

Breast metastasis is fairly uncommon and prognosis is dismal. Breast metastasis might be the first symptom or may occur during the course of other malignancies dominantly arising from the contralateral breast. Leukemia, lung cancer and conjunctival melanoma may spread to the breast.

Case presentation

A 43-year-old female patient was operated on for conjunctival melanoma. After two years the disease progressed quickly and cutaneous nodes appeared on the back and paraumbilical region. Physical and radiological examination showed a breast mass. No palpable lymph’s nodes were noted. She underwent an open biopsy. Histopathologic examination and immunohistochemistry confirmed breast metastases from melanoma. During post-operative staging multiple nasopharyngeal and oropharyngeal lesions were also objective. The patient was given palliative dacarbazine (250 mg/m² per day for 4 days) for 4 cycles. She died 4 months after the diagnosis of breast metastases.

Conclusion

Histopathological evaluation should be mandatory in patients with medical history of malignancies in order to differentiate new primary tumors, metastases, and benign tumors.

【 授权许可】

   
2014 Kharmoum et al.; licensee BioMed Central Ltd.

【 图 表 】

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