Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

BMC Research Notes

Rémi Laganier³  Siméon P Njuimo³  François Xavier Konamna³  Germain Zadanga³  Narcisse Beyam¹  Susana Vilas Boas²  Alexandre Manirakiza³ 

[1] United Nations Population Fund, Bangui, Central African Republic;Poste de santé de Mongoumba, Bangui, Central African Republic;Institut Pasteur de Bangui, PO Box 923, Bangui, Central African Republic

关键词: Central African Republic;    Treatment;    Yaws;   

Others  :  1166870
DOI  :  10.1186/1756-0500-4-543

 received in 2011-08-24, accepted in 2011-12-15,  发布年份 2011

【 摘 要 】

Background

Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region.

Findings and conclusion

The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.

【 授权许可】

   
2011 Manirakiza et al; licensee BioMed Central Ltd.

【 图 表 】

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