Anxiety-depressive disorders among irritable bowel syndrome patients in Guilan, Iran

BMC Research Notes

Siamak Bidel¹  Zahra Atrkar-Roushan³  Farahnaz Joukar³  Mahmoud Yousefi-Mashhour³  Massih Sedigh-Rahimabadi³  Seyed-Alireza Mirsafa-Moghaddam²  Ali Imani²  Fariborz Mansour-Ghanaei³  Mohamad-Jafar Modabbernia² 

[1]National Institute for Health and Welfare, Helsinki, Finland

[2]Department of Psychiatry, Guilan University of Medical Sciences, Rasht, Iran

[3]Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran

关键词: Anxiety;    Depression;    Psychiatric disorders;    IBS;   

Others  :  1166640
DOI  :  10.1186/1756-0500-5-112

 received in 2011-07-21, accepted in 2012-02-21,  发布年份 2012

【 摘 要 】

Background

Psychiatric disorders are common in irritable bowel syndrome (IBS) patients. The prevalence of psychiatric disorders in IBS patients varies in different cultures. We conducted this study to determine the prevalence of psychiatric disorders

Methods

In a cross-sectional study, 256 IBS patients were selected (using the criteria of Rome III) and evaluated for psychiatric disorders. In the first phase, subjects were screened using the General Health Questionnaire 28 (GHQ28). In the second phase, those who had scores ≥ 23 were assessed through semi-structured psychiatric interviews.

Results

Thirty out of 256 subjects had no significant psychiatric symptoms after performing GHQ28. In further psychiatric evaluation of the remaining subjects (226) who suffered from some degree of a psychiatric problem, 36 were diagnosed without Anxiety/Depressive disorder. Thus 66 subjects (25.8%) were known as a group without any significant psychiatric problem. A total of 190 subjects (74.2%) with anxiety-depressive problems were diagnosed; 89 were suffering from pure anxiety disorders, 41 were suffering from depressive disorders and 60 had co-morbid anxiety-depressive disorders. When comparing anxiety-depressive patients (n = 190) with normal subjects (n = 66), gender (P = 0.016), occupation (P = 0.002) and intensity of IBS (P < 0.001) showed statistically significant differences.

Conclusion

The high prevalence of anxiety-depressive disorders in this study indicates the necessity of psychiatric assessment, early diagnosis and treatment of the patients with IBS. It may improve management of the patients suffering from IBS.

【 授权许可】

   
2012 Modabbernia et al; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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