Independent prognostic value of left atrial function by two-dimensional speckle tracking imaging in patients with non -ST-segment-elevation acute myocardial infarction

BMC Cardiovascular Disorders

Weiting Xu¹  Jianchang Chen¹  Jing Zhu¹  Chunlai Shao¹ 

[1] Department of Cardiology, The Second Affiliated Hospital of Soochow University, Sanxiang Street 1055, Suzhou, China

关键词: Non-ST-segment-elevation acute myocardial infarction;    Left atrial function;    Strain rate;    Strain;    Two-dimensional speckle tracking imaging;   

Others  :  1230850
DOI  :  10.1186/s12872-015-0135-9

 received in 2014-05-28, accepted in 2015-10-25,  发布年份 2015

【 摘 要 】

Background

The objective of this study is to evaluate left atrial(LA) function and its prognostic value by two-dimensional speckle tracking echocardiography (STE) in patients with non-ST-segment-elevation acute myocardial infarction (NSTEAMI).

Methods

Global longitudinal LA S/SR data obtained by 2D speckle imaging with automated software (Echo PAC, GE Medical).

Results

Clinical variables and angiographic, echocardiographic, and STE parameters were studied in 65 patients with NSTEAMI (51 males and 14 females; mean age of 60.7 ± 9.8 years) who underwent elective PCI. The final study population consisted of 51 individuals (43 males and 8 females; mean age of 62.9 ± 11.1 years) and a 12 ± 3 months follow-up was performed. A total of 22 combined cardiovascular events(20 patients) occurred. With the use of Univariable Cox regression, all parameters were evaluated in the prediction of cardiac events, ischemic events, and/or cardiac death. According to ROC analysis, baseline mean global left atrial SRs (ROC area 0.82, p = 0.001) and baseline mean global left atrial SRe (ROC area 0.68, p = 0.036) were the only predictive variables.

Conclusions

In patients with NSTEAMI, we found that the novel global strain parameter of left atrial function is a valuable predictor of combined cardiovascular events over conventional echocardiography and may therefore be an important clinical tool for risk stratification in the acute phase of NSTEAMI.

【 授权许可】

   
2015 Shao et al.

【 图 表 】

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