BMC Psychiatry | |
Associations between depression and different measures of obesity (BMI, WC, WHtR, WHR) | |
Manfred E Beutel2  Yvonne Kirschner3  Andreas Schulz3  Thomas Münzel3  Maria Blettner1  Isabella Zwiener1  Philipp S Wild3  Matthias Michal2  Jörg Wiltink2  | |
[1] Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany;Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany;Department of Medicine 2, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany | |
关键词: Somatic-affective symptoms; Depression; Anthropometric measures; Abdominal obesity; Obesity; | |
Others : 1123970 DOI : 10.1186/1471-244X-13-223 |
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received in 2012-12-12, accepted in 2013-09-09, 发布年份 2013 | |
【 摘 要 】
Background
Growing evidence suggests that abdominal obesity is a more important risk factor for the prognosis of cardiovascular and metabolic diseases than BMI. Somatic-affective symptoms of depression have also been linked to cardiovascular risk. The relationship between obesity and depression, however, has remained contradictory. Our aim was therefore to relate body mass index (BMI) and different measures for abdominal obesity (waist circumference, WC, waist-to-hip ratio, WHR, waist-to-height ratio, WHtR) to somatic vs. cognitive-affective symptoms of depression.
Methods
In a cross-sectional population based study, data on the first N = 5000 participants enrolled in the Gutenberg Health Study (GHS) are reported. To analyze the relationship between depression and obesity, we computed linear regression models with the anthropometric measure (BMI, WC, WHR, WHtR) as the dependent variable and life style factors, cardiovascular risk factors and psychotropic medications as potential confounders of obesity/depression.
Results
We found that only the somatic, but not the cognitive-affective symptoms of depression are consistently positively associated with anthropometric measures of obesity.
Conclusions
We could demonstrate that the somatic-affective symptoms of depression rather than the cognitive-affective symptoms are strongly related to anthropometric measures. This is also true for younger obese starting at the age of 35 years. Our results are in line with previous studies indicating that visceral adipose tissue plays a key role in the relationship between obesity, depression and cardiovascular disease.
【 授权许可】
2013 Wiltink et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
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20150216053013808.pdf | 199KB | download |
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