The great East Japan earthquake affected the laboratory findings of hemodialysis patients in Fukushima

BMC Nephrology

Yoshiyuki Kojima¹  Hidenori Akaihata¹  Masao Kataoka¹  Souichiro Ogawa¹  Ken Kumagai¹  Norio Takahashi¹  Kei Ishibashi¹  Michihiro Yabe³  Junya Hata³  Nobuhiro Haga² 

[1] Department of Urology, Fukushima Medical University School of Medicine, Fukushima, Japan 1 Hikarigaoka, Fukushima 960-1295, Japan;Department of Urology, Soma Central Hospital, Fukushima, Japan;Department of Urology, Hanawa Welfare Hospital, Fukushima, Japan

关键词: End-stage renal disease;    Earthquake;    Hemodialysis;    Cardiothoracic ratio;    Laboratory findings;   

Others  :  1082800
DOI  :  10.1186/1471-2369-14-239

 received in 2013-05-25, accepted in 2013-10-01,  发布年份 2013

【 摘 要 】

Background

The aim of the present study was to investigate the impact of the Great East Japan Earthquake on laboratory findings in chronic hemodialysis (HD) patients in Fukushima.

Methods

Changes in laboratory findings and cardiothoracic ratio (CTR) between before and after the earthquake were retrospectively analyzed in 90 adult HD patients with end-stage renal disease (ESRD). Two hospitals located within 80 km from the Fukushima Daiichi Nuclear Power Plant, where American government recommended to evacuate from the area, participated in the study. HD duration was shortened by 0.5-1 hour for 1 month after the earthquake. Multivariate analyses were performed to identify the factors contributing to change of measurement values.

Results

Blood urea nitrogen (BUN) value was significantly transiently decreased for 1-2 weeks after the earthquake (P=0.002). In multivariate analysis, age showed a tendency to be related to the decrease of BUN level (P=0.05). Hematocrit value was significantly elevated after two months compared with that at baseline (P=0.02), although the elevation was small. The other measured values and CTR were not significantly changed compared with those before the earthquake.

Conclusions

Laboratory findings and CTR did not worsen despite the shortening of HD duration. Hence, in this disaster, as far as chronic HD patients with ESRD were concerned, it was possible for the duration of HD treatment to be safely decreased.

【 授权许可】

   
2013 Haga et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

• [1]Tsuji M, Kanda H, Kakamu T, Kobayashi D, Miyake M, Hayakawa T, Mori Y, Okochi T, Hazama A, Fukushima T: An assessment of radiation doses at an educational institution 57.8 km away from the Fukushima Daiichi nuclear power plant 1 month after the nuclear accident. Environ Health Prev Med 2012, 17(2):124-130.
• [2]Kooman JP, van der Sande FM, Leunissen KM: Role of sodium and volume in the pathogenesis of hypertension in dialysis patients. Reflections on pathophysiological mechanisms. Blood Purif 2004, 22(1):55-59.
• [3]Satoh M, Kikuya M, Ohkubo T, Imai Y: Acute and subacute effects of the great East Japan earthquake on home blood pressure values. Hypertension 2011, 58(6):e193-194.
• [4]Hwang SJ, Shu KH, Lain JD, Yang WC: Renal replacement therapy at the time of the Taiwan Chi-Chi earthquake. Nephrol Dial Transplant 2001, 16(Suppl 5):78-82.
• [5]Haga N, Hata J, Ishibashi K, Nomiya M, Takahashi N, Kojima Y: Blood pressure in hemodialysis patients after Great East Japan earthquake in Fukushima: the effect of tsunami and nuclear power accident. J Hypertens 2013, 31(8):1724-1726.
• [6]Kopp JB, Ball LK, Cohen A, Kenney RJ, Lempert KD, Miller PE, Muntner P, Qureshi N, Yelton SA: Kidney patient care in disasters: lessons from the hurricanes and earthquake of 2005. Clin J Am Soc Nephrol 2007, 2(4):814-824.
• [7]Anderson AH, Cohen AJ, Kutner NG, Kopp JB, Kimmel PL, Muntner P: Missed dialysis sessions and hospitalization in hemodialysis patients after Hurricane Katrina. Kidney Int 2009, 75(11):1202-1208.
• [8]Kenney RJ: Emergency preparedness concepts for dialysis facilities: reawakened after Hurricane Katrina. Clin J Am Soc Nephrol 2007, 2(4):809-813.
• [9]Sever MS, Erek E, Vanholder R, Kalkan A, Guney N, Usta N, Yilmaz C, Kutanis C, Turgut R, Lameire N: Features of chronic hemodialysis practice after the Marmara earthquake. J Am Soc Nephrol 2004, 15(4):1071-1076.
• [10]Naito H: Renal replacement therapy in a disaster area: the Hanshin earthquake experience (invited report). Nephrol Dial Transplant 1996, 11(11):2135-2138.
• [11]Shinzato T, Nakai S, Akiba T, Yamazaki C, Sasaki R, Kitaoka T, Kubo K, Shinoda T, Kurokawa K, Marumo F, et al.: Current status of renal replacement therapy in Japan: results of the annual survey of the Japanese Society for Dialysis Therapy. Nephrol Dial Transplant 1997, 12(5):889-898.
• [12]Ajiro J, Alchi B, Narita I, Omori K, Kondo D, Sakatsume M, Kazama JJ, Akazawa K, Gejyo F: Mortality predictors after 10 years of dialysis: a prospective study of Japanese hemodialysis patients. Clin J Am Soc Nephrol 2007, 2(4):653-660.
• [13]Inui A, Uemoto M, Uemuro T, Takamiya S, Kobayashi S, Honda M, Kasuga M, Taniguchi H: Kobe earthquake and patients with anorexia nervosa. Arch Int Med 1997, 157(4):464-465.
• [14]Inui A, Kitaoka H, Majima M, Takamiya S, Uemoto M, Yonenaga C, Honda M, Shirakawa K, Ueno N, Amano K, et al.: Effect of the Kobe earthquake on stress and glycemic control in patients with diabetes mellitus. Arch Int Med 1998, 158(3):274-278.
• [15]Inui A, Inoue H, Uemoto M, Kasuga M, Taniguchi H: Kobe earthquake and the patients on hemodialysis. Nephron 1996, 74(4):733.
• [16]Locatelli F, Del Vecchio L, Manzoni C: Morbidity and mortality on maintenance haemodialysis. Nephron 1998, 80(4):380-400.