An unusual presentation of Castleman's Disease:a case report

BMC Infectious Diseases

Martin C Mahoney¹  Kamal Tourbaf²  Ifeoma S Izuchukwu¹ 

[1] Division of Cancer Prevention & Population Sciences, Roswell Park Cancer Institute, Buffalo, NY 14263. USA;Department of Hematology & Oncology, ECMC, 462 Grider Street, Buffalo, NY 14215. USA

关键词: HHV-8;    presentation variation;    case report;    Castleman's disease;   

Others  :  1177118
DOI  :  10.1186/1471-2334-3-20

 received in 2003-04-12, accepted in 2003-09-11,  发布年份 2003

【 摘 要 】

Background

Castleman's disease (CD), a rare condition of uncertain etiology, involves a massive proliferation of lymphoid tissues and typically presents as mediastinal masses. We describe a patient with CD who presented with diffuse adenopathy involving the inguinal, paratracheal, retroperitoneal, axillary, and pelvic regions.

Case presentation

Case report describing presentation, work-up, management and clinical course of a patient with Castleman's disease in the setting of a county hospital in metropolitan area. Patient was treated with chemotherapeutic agents.

Conclusions

To our knowledge, this represents the first case of CD involving an HIV-positive patient with a negative Human Herpes Virus (HHV-8) viral panel. Because patients with similar clinical histories are at high risk for the development of non-Hodgkin's lymphoma and Kaposi sarcoma, regular medical surveillance is recommended.

【 授权许可】

   
2003 Izuchukwu et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

【 图 表 】

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